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  1. #1
    math69 is offline Junior Member
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    What's wrong with my injections!!!!!!!!!!!

    Hi all,

    I'm on T for 5 months now.
    The reason is that i'm an hypogonodal with all the symptoms that come with (lack of facial hair, young apperance....).

    My natural T level is 6.5 ng (laboratory normal: 9 - 32ng).

    4 months ago, my endoc prescribed me 1 IM 250mg / 4Weeks. I had a test at 3rd week and my level was 3.5ng!!!! (laboratory normal: 9 - 32ng).

    Then he prescribed me 1 IM 250mg / 2 Weeks. I've just received the result. 9 days after the shot my T level is 6.4ng!!! (laboratory normal: 9 - 32ng).


    Therefore, since i've started this treatment i could never see my T level in the normal range! I'm loosing my patience!! I'm even wondering if testosterone treatment is necessary???!! Cause i have the same resultat than before treatment.

    Weird...

    So, what's wrong with my injections? Is it normal? What is the lifetime of testosterone enhantate in blood? Last time I met my endoc he said that one IM / 2 weeks is a very high frequency!!
    How is is absorbed?

    Thank you.

  2. #2
    Bio-Active's Avatar
    Bio-Active is online now AR-Hall of Famer
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    test enanthate half life is about 6 days. That means at 6 days it is about half as potent. This is why your levels are low. Weekly injection are way better at half the dose!

  3. #3
    zaggahamma's Avatar
    zaggahamma is offline Mr. Moderation
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    agree with jim...should be taking 125 EVERY WEEK....so 9 days after 250mg you tested low still...like stated above the half life is less than that....but other than the numbers have you noticed any other changes other than the full beard your wanting...are you feeling better/stronger/how old are you btw?

  4. #4
    math69 is offline Junior Member
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    i feel so tired and low only 7 days aftr IM. Is it normal?
    I wonder hwy doctor can prescribe such dosage and frequency, do you have any explanations about it?

  5. #5
    fm2002 is offline Associate Member
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    My Total T levels went from around 500 to 1009 on just 125mg once per week of Test E. As mentioned if you go to once a week injections you'll see much better results.

  6. #6
    math69 is offline Junior Member
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    1009?? when did you have the test blood (how many days after injection)?

  7. #7
    fm2002 is offline Associate Member
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    Quote Originally Posted by math69 View Post
    1009?? when did you have the test blood (how many days after injection)?
    Injection on Monday blood drawn on Friday.

  8. #8
    art's Avatar
    art
    art is offline Junior Member
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    Quote Originally Posted by jim230027 View Post
    test enanthate half life is about 6 days. That means at 6 days it is about half as potent. This is why your levels are low. Weekly injection are way better at half the dose!
    Really? There is data that shows test E active half-life about 10.5 days. Is it out of date?

  9. #9
    math69 is offline Junior Member
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    Is there any product with a longer half-life? It's amazing to know that 7 days after an injection, everything is gone!
    I already know it but i had doubt, now, since my blood test i'm sure!

  10. #10
    ZonaDave's Avatar
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    everything isn't gone after 7 days. the average half-life of cypionate is 5-8 days but that can vary depending on the individual. this i vital to know for TRT. i'm sure there are guys out there who do fine on bi-weekly shots but most guys do weekly or semi-weekly shots to keep levels stabilized. stabilized T levels means stabilized E2 levels which are easier to manage. of course the drug companies are going to publish a 2 week half-life because it's appealing to the patient. i'd love to get by on one shot every two weeks but that's not reality and i enjoy feeling good.

    so lets say you took a 100mg shot on day 1. out of that 100mg only 70% is available for your body to use so about 70mg. lets say the half-life is 7 days, that means on day 7 (one week later) there is approximately 35mg in your blood. on day 14 (two weeks later) there is approximately 15.25mg is available in your blood, etc. as each 7 day period passes it's reduced by half.

    all the approved literature on cypionate says it has a half-life of 14 days but the guys on TRT know better and can feel the drop long before that. this is not an issue because most guys do self shots and they split the dose to do weekly shots regardless of what their docs tell them. the doc doesn't have to know that you do this as long as your numbers look good.

    when T was first used for replacement the ester had a very short half-life and shots had to be given daily, very similar to gels. most people hate shots to begin with so convincing a patient to go into the office daily for a shot must have been a real challenge for doctors. weekly shots with cypionate/enanthate are a minimum.

  11. #11
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    ottomaddox is offline "Better Safe Than Sorry"
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    I like to shoot every 10 days, it works better for me, less sides. I use Test-Cyp.

  12. #12
    ZonaDave's Avatar
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    there you have it! some guys like to shoot every 10 days and some like to shoot EOD.

  13. #13
    math69 is offline Junior Member
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    Thank you !
    > Ottomaddox,

    Do you know your level 9th day? I mean, you shoot every 10 days but what is your level just before the next shot?

  14. #14
    flatscat's Avatar
    flatscat is offline Knowledgeable Member
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    The thing I dont get is that our bodies make and use what - around 10mg's a day? Do you guys think the "crash" is us just coming off of the higher than normal levels and not that we don't have enough mg's available on day 7,8,9,10,11? Is it the rollercoaster of all hormone levels that is the culprit?

    I think the doctors that prescribe test c or e every two weeks or every 4 probably look at how much "should" be left in our system any given day after the injection and compare that to what a healthy male should be making daily.

    The other thing is that if we do injections more frequently that the 5-12 day half life, I would think the levels would tend to build on themselves. In other words say you take 100mg's every day 7. Say on your first day 1 you start out with 0mg's in your system. On your second injection you should theoretically be starting with 35mg's in your system. On your third, you should have 70mg's - etc, etc. Now I know our bodies will dump or convert much of this excess t. Somehow I think this is all related to trying to find that magic sweet spot and the trouble most of us have trying to get everything perfect.

    The concept of creams/gels does make sense to me as you are only adding daily what your body should be making. I just wished they worked that way. I guess the pellets use the same principle.

  15. #15
    Bio-Active's Avatar
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    Quote Originally Posted by flatscat View Post
    The thing I dont get is that our bodies make and use what - around 10mg's a day? Do you guys think the "crash" is us just coming off of the higher than normal levels and not that we don't have enough mg's available on day 7,8,9,10,11? Is it the rollercoaster of all hormone levels that is the culprit?

    I think the doctors that prescribe test c or e every two weeks or every 4 probably look at how much "should" be left in our system any given day after the injection and compare that to what a healthy male should be making daily.

    The other thing is that if we do injections more frequently that the 5-12 day half life, I would think the levels would tend to build on themselves. In other words say you take 100mg's every day 7. Say on your first day 1 you start out with 0mg's in your system. On your second injection you should theoretically be starting with 35mg's in your system. On your third, you should have 70mg's - etc, etc. Now I know our bodies will dump or convert much of this excess t. Somehow I think this is all related to trying to find that magic sweet spot and the trouble most of us have trying to get everything perfect.

    The concept of creams/gels does make sense to me as you are only adding daily what your body should be making. I just wished they worked that way. I guess the pellets use the same principle.
    It doesnt really work like that. If you are injecting 100 mg of test c per week. Week one you would start off with 10 mg of test and slowly taper down. Week 2 you would be at 15 mg and slowly taper down and so on until blood levels stable at about 19 peek and about 9 at the lowest point. do a goolge search for Roid calculater. This is a great tool for understanding half life. Alot of folks confuse half lives with active life. Best of luck

  16. #16
    ottomaddox's Avatar
    ottomaddox is offline "Better Safe Than Sorry"
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    I can't give you a certain number, because I don't know what it is, I know how I feel. I've tried injecting weekly, every two weeks, and every 10 days, and I like how I feel at 10 days. I shoot 1cc @200mg/ml. 3 days after the shot I need a little A-dex as my right nip gets a little funny feeling. I only use about a .5mg once a day for two days and I'm all good from there. Hope that helps, but you really just need to experiment with your body and see what it likes.



    Quote Originally Posted by math69 View Post
    Thank you !
    > Ottomaddox,

    Do you know your level 9th day? I mean, you shoot every 10 days but what is your level just before the next shot?

  17. #17
    Pac Man's Avatar
    Pac Man is offline Senior Member
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    Experiment a bit, listen to your body.
    I found every week worked well for me.

  18. #18
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    Isnt is optimum to inject test-e every 3.5 days?

    There were charts on here somewhere demonstrating the difference between shooting every 3.5 days and every week.

  19. #19
    warchild's Avatar
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    Quote Originally Posted by ottomaddox View Post
    I can't give you a certain number, because I don't know what it is, I know how I feel. I've tried injecting weekly, every two weeks, and every 10 days, and I like how I feel at 10 days. I shoot 1cc @200mg/ml. 3 days after the shot I need a little A-dex as my right nip gets a little funny feeling. I only use about a .5mg once a day for two days and I'm all good from there. Hope that helps, but you really just need to experiment with your body and see what it likes.
    interesting input, never would i have thought about that... when does your dc like you to give bloodwork??? mine says wait till day six and do bloodwork

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