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  1. #1
    Enden is offline New Member
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    Problem with testosterone/estrogen ratio

    I've been using arimidex since march, and experimenting with doses ranging from 1 mg twice a week to 0.25 mg every other day.

    1 mg 2x week - too much
    1 mg 1x week - not enough
    0.5 mg 2x week - not enough
    0.5 mg EOD - too much
    0.25 mg EOD - not enough
    0.25 mg ED - too much

    Now, it seems like 0.75 mg 2x week might work, but I think I've had enough. Last experiment was with 0.25 mg ED, and I developed signs of both too high and too low estrogen level. My joints were aching/clicking, and my libido was bad. Signs of low estrogen I know, but breast tissue were growing at the same time. It might be small lumps from my earlier gyno problem growing because of HGH, which I'm also using, but it's hard to tell without blood work. Anyway, when I quit arimidex, my libido returned within a week, and it went away after a drop of 0.25 mg arimidex. Additional 50 mg zink today, made my knees and ankles hurt, so I'm pretty sure that the estrogen level is too low. I'm going to wait and try to control the testosterone /estrogen ratio with andractim. This is a big challenge at the time being because I'm overweight. I'm definately going to get rid of the fat as fast as possible, but until then I need to control the ratio otherwise. Does anyone have experience with nolvadex ? Any advice appreciated.
    Last edited by Enden; 06-09-2010 at 02:04 PM.

  2. #2
    tubs is offline Associate Member
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    have you talked to your doc.? blood work? how did you come up with your list of to high /low?


    small changes with blood work is the only way to dial it in imo

  3. #3
    Vettester is offline Banned
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    Can you tell us what your E2 levels were going into it, during, after, etc? Good thing about E2 is that you don't have to hit one specific number. 20-to-40 would be good for just about anyone (male), or 25 to 35 if you're really trying to zero it in.

    Also, how does everything else look? Meaning ... Stats, BF%, diet, workout, and "T" levels? The E2 will fall in line easier if the other variables are also balanced.

  4. #4
    PPC
    PPC is offline Super Knowledgeable ~ Female Member
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    How long did you hold each dose for? Apparently it takes a couple of weeks for adex to do it's job at whatever level it is dosed at.

  5. #5
    Enden is offline New Member
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    I'm currently self-medicating without any support, but I've arranged blood work with a GP who knows everything about my situation, and he's willing to support me with further testing. The best part is that he's a good friend with an endo who's working with the clinic, so he is going to take a look at my result too. BUT I've recently done changes to my protocol, so I'll have to wait until my body is stable.

    I'm very sensitive to drugs and changes to my body in general, and I feel when the estrogen level is too low, and when it's too high. I mean, it's obvious the arimidex dose is too low if my breasts begins to grow, same the other way around, when my joints begins to ache/crack and libido disappears. I don't know what the E2 level was at the beginning, but it was high. I was better for a couple of weeks at 1 mg 2x week, but then...

    My body fat % is probably high, and that's the main problem, I think... I'm going to change my diet and workout the next weeks and take it from there, but I need to control the testosterone /estrogen ratio somehow, until I've lost enough fat. I've no idea what my testosterone level is. But it feels like it's supposed to be higher at this time. I'm currently experiementing with dosage. I'm going to do 100 mg twice a week until the blood test.

    Still interested in opinions about nolvadex .

  6. #6
    Enden is offline New Member
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    Quote Originally Posted by PPC View Post
    How long did you hold each dose for? Apparently it takes a couple of weeks for adex to do it's job at whatever level it is dosed at.
    Weeks and days. It's true when you begin treatment, but when you've lowered your estrogen level enough, a single, small dose may **** up your system for many days. Just like finasteride. Both are hardcore drugs.
    Last edited by Enden; 06-10-2010 at 12:36 PM.

  7. #7
    xpunksurferx is offline Junior Member
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    Quote Originally Posted by Enden View Post
    Weeks and days. It's true when you begin treatment, but when you've lowered your estrogen level enough, a single, small dose may **** up your system for many days. Just like finasteride. Both are hardcore drugs.
    This is true! Right now I have let it get too high..... trying to balance it out lol hae too much water and acne

  8. #8
    PPC
    PPC is offline Super Knowledgeable ~ Female Member
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    So you are not using testosterone right now? Most guys that have high E and are not using T, usually start out at around .5 mg a week. Much more than that and I fear you could go too low very quickly. Testing will be important.

    My husband had E at 38 before using any T. He took .5mg adex per week for almost a year before starting T. That dose restored his erectile function = no more ED.

    Now that he is on trt, he uses 1 mg per week in daily divided doses. It works well this way.

    But there are some who are over responders to arimidex . My Dad was one of them. Just 1mg adex per week while on trt put him at less than 7. These guys can only use 1/4 the usual dose. You may fit in that category.

  9. #9
    zaggahamma's Avatar
    zaggahamma is offline Mr. Moderation
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    Quote Originally Posted by PPC View Post
    So you are not using testosterone right now? Most guys that have high E and are not using T, usually start out at around .5 mg a week. Much more than that and I fear you could go too low very quickly. Testing will be important.

    My husband had E at 38 before using any T. He took .5mg adex per week for almost a year before starting T. That dose restored his erectile function = no more ED.

    Now that he is on trt, he uses 1 mg per week in daily divided doses. It works well this way.

    But there are some who are over responders to arimidex. My Dad was one of them. Just 1mg adex per week while on trt put him at less than 7. These guys can only use 1/4 the usual dose. You may fit in that category.
    excellent post

  10. #10
    Vettester is offline Banned
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    Quote Originally Posted by Enden View Post
    I'm currently self-medicating without any support, but I've arranged blood work with a GP who knows everything about my situation, and he's willing to support me with further testing. The best part is that he's a good friend with an endo who's working with the clinic, so he is going to take a look at my result too. BUT I've recently done changes to my protocol, so I'll have to wait until my body is stable.

    I'm very sensitive to drugs and changes to my body in general, and I feel when the estrogen level is too low, and when it's too high. I mean, it's obvious the arimidex dose is too low if my breasts begins to grow, same the other way around, when my joints begins to ache/crack and libido disappears. I don't know what the E2 level was at the beginning, but it was high. I was better for a couple of weeks at 1 mg 2x week, but then...

    My body fat % is probably high, and that's the main problem, I think... I'm going to change my diet and workout the next weeks and take it from there, but I need to control the testosterone /estrogen ratio somehow, until I've lost enough fat. I've no idea what my testosterone level is. But it feels like it's supposed to be higher at this time. I'm currently experiementing with dosage. I'm going to do 100 mg twice a week until the blood test.

    Still interested in opinions about nolvadex.
    Enden, you know this is pretty messed up, right? Experimenting with dosages and not having any idea of what your lab stats are is like driving blind. If you have no idea what your "T" level is, how do you know that you need to take 50mg opposed to 200mg? How do you know that your lipids or other values aren't being thrown off here, which could contribute to how you feel? The news that you are going to be working with a GP is the best thing that I'm seeing here.

    I'd stay clear of any Nolvadex for the time being. Also, start your diet and workout now. The next few weeks has a sneaky way of never coming around.

  11. #11
    Enden is offline New Member
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    Quote Originally Posted by PPC View Post
    So you are not using testosterone right now? Most guys that have high E and are not using T, usually start out at around .5 mg a week. Much more than that and I fear you could go too low very quickly. Testing will be important.

    My husband had E at 38 before using any T. He took .5mg adex per week for almost a year before starting T. That dose restored his erectile function = no more ED.

    Now that he is on trt, he uses 1 mg per week in daily divided doses. It works well this way.

    But there are some who are over responders to arimidex. My Dad was one of them. Just 1mg adex per week while on trt put him at less than 7. These guys can only use 1/4 the usual dose. You may fit in that category.
    I'm using testosterone enanthate , and have been doing so since the beginning of may. I've done 200 mg this week, divided into one shot with 125 mg, and another with 75 mg. I'm going to be consistent with 200 mg each week from now, divided into 2x 100 mg shots. But yeah, I see that blood testing is very important when dosing arimidex .

  12. #12
    Enden is offline New Member
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    Quote Originally Posted by vetteman08 View Post
    Enden, you know this is pretty messed up, right? Experimenting with dosages and not having any idea of what your lab stats are is like driving blind. If you have no idea what your "T" level is, how do you know that you need to take 50mg opposed to 200mg? How do you know that your lipids or other values aren't being thrown off here, which could contribute to how you feel? The news that you are going to be working with a GP is the best thing that I'm seeing here.

    I'd stay clear of any Nolvadex for the time being. Also, start your diet and workout now. The next few weeks has a sneaky way of never coming around.
    Tell me about it... I believe I'll notice side effects if I'm doing too much TE, like raging libido, acne and hairloss, which I'm prone to. I know how it's supposed to feel, as I was using testogel before testosterone injections. I could be wrong though, and I've no idea if my TRT is changing any of my other hormone levels, except E2, LH and FSH. That's why I decided to visit another clinic, after we talked a bit. Luckily I met a good doctor.
    Last edited by Enden; 06-11-2010 at 08:51 AM.

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