dopamine receptor regeneration

**SilverTest** · 06-09-2011, 07:56 AM

hey guys,

i went to my doctor after having symptoms of dopamine receptor downgrade from taking too much testosterone .

he told me that my receptors downgraded just like cocaine addicts etc..

does anyone have any information on this??? or experience??

how long until dopamine receptors regenerate? do they take a long time ??

please i am really desparate and seriously depressed about this i need my life

back, i am experiencing total anhedonia .

**zaggahamma** · 06-09-2011, 08:37 AM

sorry to hear bro....i'm mostly typing to bump this for you but can you add how much test did you take dose(s) and durations, etc,?

best of luck

**SilverTest** · 06-09-2011, 11:55 AM

i took test for 6 months in doses of about 500 mg -2 grams per week. the pros and vets here warned me about doing this but i didn't listen, i never thought something like this could happen to me, i thought that maybe i would have low test or something like that but my hormone profile right now is EXCELLENT, my test levels naturally are above 1000 ng/dl according to my last bloodwork. my thyroid is excellent , my lipids are great etc... yet i feel like total shit seriously, i am burned out a lot, i recovered a little bit, but i want to have some insight on this if anyone has any info on it . bump.

**bass** · 06-09-2011, 01:38 PM

wow 500 mgs per week for 6 months! have you checked your estrogen level?

**layeazy** · 06-09-2011, 03:58 PM

Thats alot of gear however im sure this isnt uncommon...

**steroid.com 1** · 06-09-2011, 04:51 PM

I got to believe that there's probably a lot more wrong with you as well. At that dosage for that period of time can do some real damage. If I were you I'd go to a top notch Endo and get a full blown eval done and plan a course of action. WOW!

**JD250** · 06-09-2011, 06:43 PM

Hold on........you didn't say 500mgs a week......you said 500 mg doses at 2 GRAMS a week........basically you were taking 500mgs EOD for 6 months.....right?

**Black** · 06-09-2011, 06:57 PM

I would also post this over in the Steroid Main Forum, just because of the strength of your doses/cycles.

**steroid.com 1** · 06-09-2011, 07:05 PM

Originally Posted by Dante Diamond

I would also post this over in the Steroid Main Forum, just because of the strength of your doses/cycles.

+1 as well.

**bass** · 06-09-2011, 10:51 PM

Originally Posted by JD250

Hold on........you didn't say 500mgs a week......you said 500 mg doses at 2 GRAMS a week........basically you were taking 500mgs EOD for 6 months.....right?

i hope you're wrong JD! what pharmacy can supply that much anyway?!

**SilverTest** · 06-10-2011, 08:26 AM

ok guys, first of all, ALL my hormonal bloodwork is EXCELLENT right now, i already did bloodwork for everything including estrogen which is great. i used BETWEEN 500 and 2 grams per week of test for 6 month .

**bass** · 06-10-2011, 12:50 PM

glad your blood work is good! a gram is a 1000 mgs, so you used between 500-2000 mgs per week?! so i am assuming some of your doses were 2000 mgs per week!

**zaggahamma** · 06-10-2011, 12:54 PM

Originally Posted by bass

glad your blood work is good! a gram is a 1000 mgs, so you used between 500-2000 mgs per week?! so i am assuming some of your doses were 2000 mgs per week!

lol...i dont think the guy is confused about the doseage amounts....he said he was warned and did it anyway..

silver, what is your doctors recommendation/plan at this point?

**bass** · 06-10-2011, 01:40 PM

i guess so! thats two vials of 10 ML per dose! i wonder what size syringe he used! unless he was shooting daily at 300 mgs...

**JD250** · 06-10-2011, 10:09 PM

I don't claim to know much about heavy cycles.......I was just trying to wrap my mind around the "2 grams a week" , It took me a minute to grasp the size of that dose and for that length of time. Interesting that the labs came back perfect. Not to drag this on further but why would your dose be between 500mg and 2 grams per week......thats a variance of 400%....not real steady.....sorry, I just cant make sense of any of this. What kind of gains did you make on that dose?

**zaggahamma** · 06-10-2011, 10:22 PM

Originally Posted by JD250

I don't claim to know much about heavy cycles.......I was just trying to wrap my mind around the "2 grams a week" , It took me a minute to grasp the size of that dose and for that length of time. Interesting that the labs came back perfect. Not to drag this on further but why would your dose be between 500mg and 2 grams per week......thats a variance of 400%....not real steady.....sorry, I just cant make sense of any of this. What kind of gains did you make on that dose?

ditto

**bass** · 06-10-2011, 10:41 PM

maybe fake gear!

**GotNoBlueMilk** · 06-11-2011, 05:11 AM

Originally Posted by JD250

Interesting that the labs came back perfect

My understanding from his post is that he WAS doing Test in large amounts, is no longer taking Test, and his labs NOW after being off the Test are perfect.

**SilverTest** · 06-11-2011, 08:36 AM

ya guys actually i took up to 2000 mgs per week of test.

here is some of my lab bloodwork about 8 months after the last pct i did :

total testosterone range : 200-800 result:1093 ng/dl

prolactin range : 4.04-15.2 result: 23.59 ng/ml

estradiol range : 7.63-42.6 result: 24.58 pg/ml

this is my thyroid panel while OFF:

Free T3 4.02 pg/ml range 2.0-4.4
Free T4 1.41 pg/dl range 0.93-1.7

TSH 1.89 microUI/ml range 0.27-4.2

this is my lipid panel while ON:

ipids:

total cholesterol 193 mg/100 ml range <200
triglycerides 65 mg/100 ml range <150
HDL 49 mg/100 ml range >40
LDL 128 mg/100 ml range <130

ratios:

total cholesterol/HDL cholesterol 3.94 risk >4.97
LDL /HDL 2.61 risk >3.55

my doctors recommendation is to just abstain from anything stimulant including natural stuff and i might say he is right, suprisingly, i am begining to feel really good these few days i see a lot of sudden improvement

libido is going up energy is back up , everything's is good!

**SilverTest** · 06-11-2011, 08:39 AM

Originally Posted by JD250

I don't claim to know much about heavy cycles.......I was just trying to wrap my mind around the "2 grams a week" , It took me a minute to grasp the size of that dose and for that length of time. Interesting that the labs came back perfect. Not to drag this on further but why would your dose be between 500mg and 2 grams per week......thats a variance of 400%....not real steady.....sorry, I just cant make sense of any of this. What kind of gains did you make on that dose?

i cycled my doses , like cruising on 500 then bumping it to 2000 etc...u get the picture.

**GotNoBlueMilk** · 06-11-2011, 09:19 AM

I wonder if your high prolactin is contributing to your crappy feeling.

Intersting that your T is so high yet you haven't done any T in 8 months.

**SilverTest** · 06-11-2011, 09:36 AM

Originally Posted by GotNoBlueMilk

I wonder if your high prolactin is contributing to your crappy feeling.

Intersting that your T is so high yet you haven't done any T in 8 months.

the high prolactin is from dopamine receptor downgrade.

regarding my natty test levels, actually the endo couldn't believe that i was actually OFF, he requested a LH test which i did and came back normal high, the max range was 8.8 mine came back as 7.4 which convinced him that i had naturally very high test levels, keep in mind that my test will be even higher as my prolactin goes down.

**GotNoBlueMilk** · 06-11-2011, 09:41 AM

Ok, you have naturally high T levels. Sorry man, but at this point I care very little about your problem . . . I want to know how I can get those naturally high T levels!

**SilverTest** · 06-11-2011, 09:45 AM

Originally Posted by GotNoBlueMilk

Ok, you have naturally high T levels. Sorry man, but at this point I care very little about your problem . . . I want to know how I can get those naturally high T levels!

well, it runs in the family

hahaha, no seriously i always had those levels thank god i recovered. In addition, i am still relatively young i'm 24 yo. How old r u ?

**GotNoBlueMilk** · 06-11-2011, 10:04 AM

Originally Posted by SilverTest

well, it runs in the family

hahaha, no seriously i always had those levels thank god i recovered. In addition, i am still relatively young i'm 24 yo. How old r u ?

52 y/o here. I have no clue what my T levels were when I was 24, but I am postive they never broke 800.

Now that I am convinced you aren't just claiming to be off T, I have given your issue some thought.

First, from personal experience, low D is a killer. I felt crappy, and taking 10,000 IU's of D made me feel 100% better in just a week. You can get a blood test to see where you D is at. You want to shoot for mid-range. Turns out Vitamine D plays a role in dopamine too: http://www.livestrong.com/article/33...-for-dopamine/ But Vitamine D is toxic, so you don't want to do D if you have high D already. Try taking 5,000 IU's everyday for a week. No change, then not much point in continuing unless you get a blood test done and you are deficient.

Not much info on regerating dopamine receptors unless you are a salmander or a rat. And those articles were pretty useless.

**SilverTest** · 06-11-2011, 11:48 AM

Originally Posted by GotNoBlueMilk;5665***

52 y/o here. I have no clue what my T levels were when I was 24, but I am postive they never broke 800.

Now that I am convinced you aren't just claiming to be off T, I have given your issue some thought.

First, from personal experience, low D is a killer. I felt crappy, and taking 10,000 IU's of D made me feel 100% better in just a week. You can get a blood test to see where you D is at. You want to shoot for mid-range. Turns out Vitamine D plays a role in dopamine too: http://www.livestrong.com/article/33...-for-dopamine/ But Vitamine D is toxic, so you don't want to do D if you have high D already. Try taking 5,000 IU's everyday for a week. No change, then not much point in continuing unless you get a blood test done and you are deficient.

Not much info on regerating dopamine receptors unless you are a salmander or a rat. And those articles were pretty useless.

thanks for the help man i appreciate it

i will stick to my doctors recommendations right now since its working and i am feeling better an better these past few weeks suddenly.

by the way, why dont you take a bloodtest to see where ur test levels are at, it can really change your life if u have low t and get on TRT !

**JD250** · 06-11-2011, 01:44 PM

Almost everyone in this forum is on TRT, and maybe a little more from time to time.

Glad you're feeling better.....what kind of gains did you have during that cycle.

**bass** · 06-11-2011, 01:49 PM

Originally Posted by JD250

Glad you're feeling better.....what kind of gains did you have during that cycle.

i like to know as well!

**SilverTest** · 06-11-2011, 11:15 PM

Originally Posted by bass

i like to know as well!

actually not much, just some 20 lbs i think some of it is just fat, gains in strength were kind of standard just like any cycle, i didn't really monitor my gains precisely at all errr, which is kind of a bad move. but if you want to know the truth about whether you stop gaining or you continu to gain, i can tell you that gains stop at the usual 3 months mark just like normal cycles, unless you increase the dosage and so on, its a never ending cycle, you have to increase the dose to keep gaining which is bad in my opinion. OR you have to cruise and blast. All in all, i do not recommend long cycles, and i will pretty much never do it again, cycling and taking time off is the way to go guys, and i learned that the hard way.

**bass** · 06-12-2011, 12:34 AM

wow thats allot of gear just for 20 pounds and some of it is fat! i think staking is the best, not just test alone! and like you said shorter periods, no more than 12 weeks!

**SilverTest** · 06-12-2011, 02:08 AM

Originally Posted by bass

wow thats allot of gear just for 20 pounds and some of it is fat! i think staking is the best, not just test alone! and like you said shorter periods, no more than 12 weeks!

ya bro, in all honesty, it was not worth it at all.I get kind of depressed when i remember it.

**lovbyts** · 06-12-2011, 02:18 AM

I'm not even sure what to say.... Glad you recovered. I cant imagine why you though that much gear for that long would be a good idea. I'm glad/hope you learned something from it. If you had not had something to scare you then you probably wouldn't have. I never understood the it wont/cant happen to me attitude.... I guess I have seen/read to many times where it's obvious it can/does happen.

Dont we all with we had our testosterone levels checked at 24 so we had a base line? I imagine mine where also good since I had naturally good genetics, made quick gains. If I had known anything about diet OMG I could have been big. LOL Like most 24 yr olds I had a good/high libido also but even will into my early 40s it was high even when I had low T. I think part of it is just an active imagination and to much free time surfing porn. lol

**SilverTest** · 06-12-2011, 02:24 AM

Originally Posted by lovbyts

I'm not even sure what to say.... Glad you recovered. I cant imagine why you though that much gear for that long would be a good idea. I'm glad/hope you learned something from it. If you had not had something to scare you then you probably wouldn't have. I never understood the it wont/cant happen to me attitude.... I guess I have seen/read to many times where it's obvious it can/does happen.

Dont we all with we had our testosterone levels checked at 24 so we had a base line? I imagine mine where also good since I had naturally good genetics, made quick gains. If I had known anything about diet OMG I could have been big. LOL Like most 24 yr olds I had a good/high libido also but even will into my early 40s it was high even when I had low T. I think part of it is just an active imagination and to much free time surfing porn. lol

ya man it was pretty stupid to do. But since i recovered, all my hormones are GREAT, AND i am studying to become a fitness trainer so i have everything i need to grow and advance even without gear. I think i am really lucky