What to take for ED

[wayneb]

I am 74 and have erectile dysfuntion; have tried Viagra and Cialias to no avail. What hormone replacement would help me with this problem? I may be simplifying the situation; but I have had both testestrone and HGH treatment recommended by friends. Any suggestions on which road to follow?

[steroid.com 1]

It can help. The last numbers I saw were 30% of men with ED on TRT onlly protocols solved their ED problem. 60% of men on combined TRT and PDE-5 inhibitors overcame ED issues. So, it can help. ED is a complex medical condition believe it or not and many things well beyond low Test can cause it. Have stress or worry a lot...that's like #1 on the ED list.

See a good Anti-Aging Doc in your area to help you...not friends.

See below, this should help you Wayne:





J Sex Med. 2011 Aug 11. doi: 10.1111/j.1743-6109.2011.02436.x. [Epub ahead of print]

Improved Sexual Function with Testosterone Replacement Therapy in Hypogonadal Men: Real-World Data from the Testim Registry in the United States (TRiUS).

Khera M, Bhattacharya RK, Blick G, Kushner H, Nguyen D, Miner MM.


Source

Scott Department of Urology, Baylor College of Medicine, Houston, TX, USA Department of Internal Medicine, University of Kansas Medical Center, Kansas City, KS, USA Circle Medical LLC, Norwalk, CT, USA Department of Biometrics, Auxilium Pharmaceuticals, Malvern, PA, USA Department of Medical Affairs, Auxilium Pharmaceuticals, Malvern, PA, USA Miriam Hospital Men's Health Center, Warren Alpert School of Medicine, Brown University, Providence, RI, USA.


Abstract

Introduction.  Up to 30% of erectile dysfunction (ED) patients treated with phosphodiesterase type 5 (PDE5) inhibitors do not show improved sexual function, which may be due in part to low serum testosterone . Hypogonadal patients already receiving testosterone replacement therapy (TRT) likewise can still suffer from symptoms of sexual dysfunction. In these patient populations, augmenting with, or switching, TRT treatment may improve sexual function. Aim.  To determine if 12-month treatment with a testosterone gel improves sexual function in hypogonadal men, as measured by the Brief Male Sexual Function Inventory (BMSFI), and in subgroups defined by low testosterone , PDE5 inhibitor use, and prior TRT. Methods.  The Testim Registry in the United States (TRiUS) was a large (N = 849) multicenter registry of hypogonadal men treated with Testim (testosterone 1%) topical gel and followed for 12 months. Main Outcome Measures.  Data collected at suggested visits (baseline; 1, 3, 6, and 12 months) included total testosterone (TT), free testosterone (FT), BMSFI scores, physical exam, and body measurements. Results.  TRiUS had 271 patients with baseline testosterone and BMSFI measurements. At 12 months of TRT, TT and FT levels significantly increased from baseline (P < 0.001), with mean ± standard deviation final TT = 17.37 ± 8.61 nmol/L (500.6 ± 248.2 ng/dL) and FT = 240.1 ± 296.0 pmol/L (69.2 ± 85.3 pg/mL). The mean total BMSFI score significantly increased from baseline at 12 months (27.4 ± 10.3 to 33.8 ± 9.8, P < 0.001) and at each visit in all domains (sex drive/libido, erectile function, ejaculatory function, level of bother), overall and for all subgroups. Regression analysis indicated that increased total BMSFI score was significantly associated with increased TT levels at 6 months. Conclusions.  In hypogonadal patients, 12-month administration of topical testosterone gel resulted in increased TT and FT levels and significantly improved sexual function. All subgroups studied, including men taking PDE5 inhibitors for ED and those previously on TRT, demonstrated significant improvement in sexual function from baseline scores. Khera M, Bhattacharya RK, Blick G, Kushner H, Nguyen D, and Miner MM. Improved sexual function with testosterone replacement therapy in hypogonadal men: Real-world data from the Testim Registry in the United States (TRiUS). J Sex Med **;**:**-**.

© 2011 International Society for Sexual Medicine.

Testosterone replacement therapy in males with erectile dysfunction.



Testosterone replacement therapy in males with erectile dysfunction.

J Pharm Pract. 2011 Jun;24(3):298-306

Authors: Jacob BC

Erectile dysfunction (ED) is defined as the inability to achieve or maintain an erection sufficient for satisfactory sexual performance. Endogenous testosterone is critical for normal libido; however, studies have also demonstrated a potentially important role with respect to the erectile process. The prevalence of testosterone deficiency ranges from 1.7% to 35% in patients with ED, and age is a common factor linking ED and testosterone deficiency. By 2025, global estimates are that there will be 356 million men >65 years. Age-associated testosterone deficiency is characterized by symptoms such as ED, and low serum testosterone. Randomized, placebo controlled studies have established the utility of testosterone replacement therapy (TRT) for the restoration of serum testosterone levels to the normal range in hypogonadal males; however, well designed studies are limited with respect to specific evaluation of the role of TRT as monotherapy in improving erectile function. In addition, recent literature suggests a possible role for TRT in combination with phosphodiesterase-5 (PDE-5) inhibitors for men with ED. The following review describes the potential roles of testosterone in erectile physiology, examines the relationship between testosterone deficiency and ED, and reviews published literature evaluating the use of TRT in hypogonadal males with a diagnosis of ED.

PMID: 21676853 [PubMed - in process]



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[APIs]

Are you under the care of a Doctor that knows your situation? I only ask because ED can also be an early sign of underlying Heart/Pulmonary problems. Many Doctors now give a thorough Heart exam at the first sign of ED...