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  1. #1
    alexenvalencia's Avatar
    alexenvalencia is offline New Member
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    Anastrozole side effects and is it really necessary to add HCG to standard TRT?

    31 years old - went on TRT after having low libido and energy for 3 or 4 years - probably due to a year of high stress at work and resultant use of SSRI for 3 years. My free Test was evaluated borderline low so Urologist decided to trial TEST CYP IM at 50mg. On reading and researching myself the Crisler protocol, decided to add some HCG and anastrozole.

    Current regime:
    50mg TEXT CYP E3D
    250IU HCG E3D
    0.25mg ANASTROZOLE E3D

    Started TRT beginning of April, End of June added HCG and End of July added ANASTROZOLE.



    First few months up to end of July, improvement in libido and energy no doubt. Then over August (IMO coinciding with adding the ANASTRAZOLE, initially at 0.25 E2D) start to feel weak and muscle/joint achy on getting up in the morning, some muscle weakness during the day, reduced libido.

    I reduced the ANASTRAZOLE to 0.25 E3D a month ago and did a blood test. E2 had risen from my pre TRT baseline to 31 pg/ml which I think may be a little above the ideal. Also the TT level is about 200 too high (800 would be good) with resultant acne issues on my back and arms.

    Could the muscle weakness and aches be a side effect of the anastrazole or even of too low/ too high E2?

    Is HCG really a necessary addition to a simple TRT of 50mg TEST CYP E3D? My thinking is that I remove the HCG, test levels drop into the 700-800 range and thus I can try removing the Anastrazole due to lower aromatisation. Instead of 3 meds, I would be on 1 as the urologist originally intended. Any opinions?

  2. #2
    doctor jim is offline New Member
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    Have some similar issues. Let me know what you find out.

  3. #3
    Brohim's Avatar
    Brohim is offline Senior Member
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    Yes achy joints and low sex drive is from you crashing the e2 wiht too much Anti-E. 30 is a good range so try to keep it there.

    There is not 1 fit all. Signs of high E is puffy/itchy nipples and water retention. If you have those use a anti-E to try to correct. Some guys can be on 200mg/wk and there e2 is fine and some guy's 100/week and need a anti-E.

  4. #4
    zaggahamma's Avatar
    zaggahamma is offline Mr. Moderation
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    i would lower the test dosage before losing the hcg

    3 pokes a week is a lot of jabbin imo anyway...suggest 2 pokes totalling 100mg?

    my .02

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