Half Life

[bullshark99]

Picking this up off Teddy's post, Bass expained half life, reading it I knew exactly where he was going, vette08 "polietly"clarified him that he was referring to serum peak. My question/confusion is half life for T is about 7 or 8 days? Does this not mean that in 7 or 8 days the amount of drug (this case T) is 50% the amount or stength that was initially injected? If so, what confuses me, we then inject again on day 7, we still have 50% of the previous meds in our system, wouldnt we be at superficial levels at this point? More importantly, the compounding effect 6-8 weeks down the road. The T most not be very stable after it hits its half life and is deposed of pretty quick?
Pretty confusing if you ask me

[pugster]

think of it like a sine wave , the uptake is not instantaneous either (plasma concentration builds upto a steady state) , as your previous injection drops off your next injection is building up , the aim is to balance this so the sine wave shows very little highs and lows (peaks and troughs).

[steroid.com 1]

You got it pretty much correct.

Half life is half life; in other words, 50% of the remaining serum level (for the most part) will metabolize out in about every 7 days.

When you start up a protocol you are building serum levels to where they will stabilize and half life becomes less of an issue and levels pretty much remain constant.

It's another reason for doing smaller dosages but inject more frequently as it flattens the half life curve and serum levels become even more stable...plus the benefits of E2 management.

[bullshark99]

Never thought of it that way, that makes sense!

[pugster]

i'll be glad when i can post a dam pic or link to make explaining things easier :P

[zaggahamma]

I go to wiki or web md for definitions

[SEOINAGE]

You won't be at superficial levels because the half life stays the same, it is also why it takes a few weeks or more to reach stable levels. So lets use numbers, inject 100, one week later 50 is in your system inject 100, one week later 75 is in your system inject 100, next week 87.5 is in your system, add 100, next week 93.75 add 100, eventually it will get to be 99.999999999999999999 but it won't go beyond that. Because you will be adding 99.9 to 100 and dividing by 2 will always be under 100. Basically with half lives taken the same amount regularly you reach a full saturation that is not surpassed unless more is added. This is the simplest way I can explain it without getting into individuals responses and actual t levels etc.

[bullshark99]

Actually that again makes sense, goes to show why Dr's that inject every 2 or 3 weeks does not work

[flatscat]

You won't be at superficial levels because the half life stays the same, it is also why it takes a few weeks or more to reach stable levels. So lets use numbers, inject 100, one week later 50 is in your system inject 100, one week later 75 is in your system inject 100, next week 87.5 is in your system, add 100, next week 93.75 add 100, eventually it will get to be 99.999999999999999999 but it won't go beyond that. Because you will be adding 99.9 to 100 and dividing by 2 will always be under 100. Basically with half lives taken the same amount regularly you reach a full saturation that is not surpassed unless more is added. This is the simplest way I can explain it without getting into individuals responses and actual t levels etc.

So then once saturation is hit at 99.9 why would more frequent injections make a difference? you would just hit saturation level sooner?

[SEOINAGE]

well lets say with once a week you inject 100, you obviously wont have 200 in your system since it takes a while to reach max levels but to make it easy lets say you inject 100 when you still have 99.9 in you are at 200. so you go from 200 to 100 to 200 to 100, thats a huge difference in the amount present. so lets say you are doing 50 two times a week since half life is still roughly 7 days, after day 3.5 you are at something like 3/4s of the amount. so inject 50 at next inject you will be at 37.5, of course not really the case since it takes a while to saturate, but for analyzing it we can once again ignore that fact, but that fact also means levels won't have as big of a spread. Ok so you add another 50 bringing you up to 87.5 3.5 days later you are down to 65.625. add 50 then 3.5 day slater sitting at 86.72, then 102.54, EVENTUALLY its limit is 149.999999, so you will be fluctuating from 200 to 150 with a longer period to stabilize readings. This can be shown with a calculus equation and limits but I am avoiding anymore calculus if I can.

so you have a fluctuation of 200 to 100 spread over a week, or a fluctuation of 200 to 150 spread over a few days. Which one is obviously going to make you feel more normal and even?

[kelkel]

I never liked you calculus guys in college.

[pugster]

Actually that again makes sense, goes to show why Dr's that inject every 2 or 3 weeks does not work

they work as long as the right test ester is used , longer half life + longer time between injection= longer time to stabilise ,short half life +short time injection=short time stabilised , short half life+long time inject=no good for anything

[zaggahamma]

I never liked you calculus guys in college.

lets beat the fvck out of em

[flatscat]

Okay now explain saturation duration based on your last two scenarios.

[flatscat]

lets beat the fvck out of em

Killing me.... Lmfao

[buttslinger]

I have to go to my urologist and this thread has spooked me. He kinda scowled at my last testosterone blood test (1070- range 250-1100) because he wanted me to take 67units per week of testcyp200.
And this didn't add up. What do I have to do to get my number down, skip 3 weeks?

[bass]

what is 67 unit of test cyp 200? were you injecting 200 mgs while he prescribed 67 mgs? and why do you want to trick your doctor? start your own thread!

[buttslinger]

what is 67 unit of test cyp 200? were you injecting 200 mgs while he prescribed 67 mgs? and why do you want to trick your doctor? start your own thread!

67 units is 67mg/mL. I am not injecting 200 mgs, I'm injecting a little over 100mg/week. My vial is 200mg/mL. I am asking about halflife, check the name of the thread.
My doctor prescribed me testim first, I talked him into injectable, and I talked him out of injecting every 3 weeks. I'm not tricking my doctor, I'm building up a rapport with him. Can you understand that?

[SEOINAGE]

Okay now explain saturation duration based on your last two scenarios.

What do you mean? the half life's are the same just depends on the amount in you at a given time. Only thing I didn't explain is how different people react and how long it takes for it to get in your blood and where your test levels go, which I really can not answer. Everyone says your actual test levels peak after 3-4 days from a shot, dunno how true it is, at least the last few shots I have had I am immediately horny not long after and don't experience that again till the next shot, but that was really only 2 out of 3 shots so I'm new to this so could be in my head anyways.

[SEOINAGE]

67 units is 67mg/mL. I am not injecting 200 mgs, I'm injecting a little over 100mg/week. My vial is 200mg/mL. I am asking about halflife, check the name of the thread.
My doctor prescribed me testim first, I talked him into injectable, and I talked him out of injecting every 3 weeks. I'm not tricking my doctor, I'm building up a rapport with him. Can you understand that?

He doesn't understand your question, nor do I.

[bass]

I have to go to my urologist and this thread has spooked me. He kinda scowled at my last testosterone blood test (1070- range 250-1100) because he wanted me to take 67units per week of testcyp200.
And this didn't add up. What do I have to do to get my number down, skip 3 weeks?

what does this questions have to do with half life, sir!

[DaRoq]

67 units is 67mg/mL. I am not injecting 200 mgs, I'm injecting a little over 100mg/week. My vial is 200mg/mL. I am asking about halflife, check the name of the thread.
My doctor prescribed me testim first, I talked him into injectable, and I talked him out of injecting every 3 weeks. I'm not tricking my doctor, I'm building up a rapport with him. Can you understand that?

What's your current dose? It seems like you're trying to keep it the same or increase it by lowering your test levels, which basically IS trying to trick him. It might've worked on your first follow-up, but now I think it would be an insult to his intelligence if all of the sudden your levels supposedly dropped on your current dose.

[buttslinger]

Let's see if I can make myself clear. The range for testosterone health and fitness is 250-1200. My Johns Hopkins doctor told me I want to hit dead center between 525 and 1200,(about 850) I have all my bloodwork for 1070, LH, free test, estradiol, etc.
I would now like to see what my levels all look like at about 550. Since I tested my blood lasat time 2 days after injecting, my plan this time was to inject 8 days before my blood work was done, presuming it would go down to about 550. Then I could see what my estradiol and DHA and all the rest were doing at that level.
Now I read that it takes a few weeks to get blood levels UP, will it take a few weeks to get my 1070 DOWN to 550? If I'm not clear, tell me, I do appreciate the help.

[kelkel]

Butts when was blood pulled relative to your prior injection?

[buttslinger]

What's your current dose? It seems like you're trying to keep it the same or increase it by lowering your test levels, which basically IS trying to trick him. It might've worked on your first follow-up, but now I think it would be an insult to his intelligence if all of the sudden your levels supposedly dropped on your current dose.

Like I said above, I was going to tell him the truth,that I injected 2 days before bloodwork the first time, and ask him to retest 8 days after injection. My Johns Hopkins doctor is 2 hoursa away, this urologist is LITERALLY 5 minutes away. If I have to use a little ROMANCE, I will. My current dose is about 100mg.

[zaggahamma]

wasnt this bullshark's thread at one time

[bass]

wasnt this bullshark's thread at one time

LOL! thats what i keep saying, but Butts still hasn't started his own thread.

[buttslinger]

Let me try this: If I inject 100 mg of test today, how long before it's all out of my system? Based on Halflife.

[SEOINAGE]

Let me try this: If I inject 100 mg of test today, how long before it's all out of my system? Based on Halflife.

Like test cyp? 18 days for most of it out of your system, but not completely.

[buttslinger]

So if I take 100mg of test cyp today, in one week it will be 50mg, in two weeks 25?
Does it chart down like a line or a curve?
I was under the impression that after 7-8 days, ALL that test would be gone and that's why you have to reboot.

[pugster]

it takes longer to get stuff out your system than what you think
so 100-50-25-12.5 etc etc
so looking at above if something had a halflife of 7 days then it would take 21 days to hit the 25% mark

you dont reboot anything, as ive said before its llike a sine wave as your last shot is dropping off your next shot is building up
i.e draw a sine wave this is your first shot
advance a cm and draw another over the top , where the peaks are is your top plasma level , the valleys are the drop off , as you add more and more shots to the sine wave moving forward each time the valleys move up towards the peaks , this is your steady state.

ffs someone post a pic explaining this (i can post them yet), tho tbh i still dont get why so many ppl want to deceive their docs.

[buttslinger]

My estradiol was high when my blood came back at 1070. My doctor's cure for that is to cut way back on my test, not to add an A1. If I can get my blood down to 550, and the estradiol is still high, my Johns Hopkins doctor can step in and talk about an A1. When I talk about HCG , they look at me like a junkie looking for an oxy prescription.
There are actually TWO chartwaves rolling here, the 100-50-25-12.5 chartand the Testosterone Total chart, which is measured in ng/dL and should always fall between 250 and 1200. The second chart is the more important one and other factors contibute to that chart, besides the dose of test. So for me personally, I'm trying to figure out what dose when will bring me down to 550.
I can't figure out how to make an attachment on this site, or I'd post up some chalkboard wave graphs. Although the 100-50-25-12.5 chart sounds like a line graph.

[pugster]

100-50-25-12.5 etc is not a chart, its the half life decay rate, each time it drops by 50% of the previous (12.5 is not the end im just too idle to keep halving it to show you)

[zaggahamma]

E equals mc*mc*1

What's the square root of the ester when sq injections thrust protocol based on 50 mg bi weekly

[buttslinger]

8,449

[pugster]

there ya go , jpkman has it

to summarise , stop injecting till you feel like shit then you are low enough to fool doctor

[bass]

guys stop responding to Butts so he can start his own thread. this thread has officially been hijacked! LOL!

[buttslinger]

yeah guys, do what bass says.
My question is 100% about HALFLIFE.
Keep an eye out for my new thread, "Get a Life" 3,600 posts. LOL!
OK Now you can stop responding!!!

[zaggahamma]

Hope u enjoyed your stay troll

[buttslinger]

Haw haw haw