Horny Goat Weed?

[Stevens03]

Have any of you guys used it? Since I'm younger then most men with Low T, I wanted to take a more natural route to boost libido. I have read many good reviews on HGW but I'm still skeptical.

[jwh7699]

I've taken it before, it has panax ginseng, which is the main ingredient. It worked for me once, the second time no effect.

[Times Roman]

Have any of you guys used it? Since I'm younger then most men with Low T, I wanted to take a more natural route to boost libido. I have read many good reviews on HGW but I'm still skeptical.

waste of money

I've taken it before, it has panax ginseng, which is the main ingredient. It worked for me once, the second time no effect.

1st time was a placebo effect

[jwh7699]

Keep in mind ED is not always physical. If you're stressed or haven't been sleeping well this can lead to problems too. It's best to address any outside issues before taking something, because it can lead to you feeling like you have to take something every time. It happens to everyone from time to time even if they won't admit it.

[Stevens03]

I'm relaxed as can be and get 8 hours of sleep every night. I just don't want to start taking any of the prescribed stuff yet, due to my age.

[anon77]

I'm relaxed as can be and get 8 hours of sleep every night. I just don't want to start taking any of the prescribed stuff yet, due to my age.

I don't blame you. I've heard of serms helping get things kickstarted for guys. Maybe ask your Dr.

[steroid.com 1]

The main ingredient in Horny Goat Weed is Icarrin a proven PDE5i...however, dosage needs to be much higher then what we can buy here.

There is an Icarrin 60 which I have taken as part of my stack and can say it worked but not like Tadalafil.

[Stevens03]

What do you guys recommend I buy. Like I said, I don't want anything with a prescription yet. I want to try some over the counter stuff first.

[Times Roman]

The main ingredient in Horny Goat Weed is Icarrin a proven PDE5i...however, dosage needs to be much higher then what we can buy here.

There is an Icarrin 60 which I have taken as part of my stack and can say it worked but not like Tadalafil.

and the way it is processed and sold, ground up, it is not very bio available.

there is a big difference in effect between chewing on sugar cane.....

....and putting a teaspoon of sugar in your coffee.

The horney goat weed commonly sold is in serious need of more refinement, which makes it ineffective, imo

[juice work]

i recommend a better looking gf

go buy some p6 made by cellucor at gnc and that will have you ****en your wall broski

[jwh7699]

Some people take L-Arginine, it helps increase blood flow.

[steroid.com 1]

and the way it is processed and sold, ground up, it is not very bio available.

there is a big difference in effect between chewing on sugar cane.....

....and putting a teaspoon of sugar in your coffee.

The horney goat weed commonly sold is in serious need of more refinement, which makes it ineffective, imo

Totally agree TR.

Here's where I get the Icarrin 60: http://www.worldabs.com/products/hor...riin-epimedium

It's the highest potency one can buy and they claim the highest standards in processing.

Honestly, I think taking a high quality BB NO2 amino stack would help the cause.

OTC stuff for increasing erection quality is extremely poor...

Rise of herbal and traditional medicine in erectile dysfunction management.

Ho CC, Tan HM.


Source

Department of Surgery, Universiti Kebangsaan Malaysia Medical Centre, Jalan Yaacob Latif, Bandar Tun Razak, 56000 Cheras, Kuala Lumpur, Malaysia.


Abstract

Herbal medicine long has been used in the management of sexual dysfunction, including erectile dysfunction. Many patients have attested to the efficacy of this treatment. However, is it evidence-based medicine? Studies have been done on animal models, mainly in the laboratory. However, randomized controlled trials on humans are scarce. The only herbal medications that have been studied for erectile dysfunction are Panax ginseng, Butea superba, Epimedium herbs (icariin), Tribulus terrestris, Securidaca longipedunculata, Piper guineense, and yohimbine. Of these, only Panax ginseng, B. superb, and yohimbine have published studies done on humans. Unfortunately, these published trials on humans were not robust. Many herbal therapies appear to have potential benefits, and similarly, the health risks of various phytotherapeutic compounds need to be elucidated. Properly designed human trials should be worked out and encouraged to determine the efficacy and safety of potential phytotherapies.

Of course we're not castrated rats...well most of us any way...this is interesting. Note the purity as noted by TR in the Conslusion.

Effects of icariin on erectile function and expression of nitric oxide synthase isoforms in castrated rats.

Liu WJ, Xin ZC, Xin H, Yuan YM, Tian L, Guo YL.


Source

Andrology Center of Peking University First Hospital, Beijing 100009, China.


Abstract

AIM:

To investigate the effect of icariin on erectile function and the expression of nitric oxide synthase (NOS) isoforms in castrated rats.

METHODS:

Thirty-two adult male Wistar rats were randomly divided into one sham-operated group (A) and three castrated groups (B, C and D). One week after surgery, rats were treated with normal saline (groups A and B) or oral icariin (1 mg/[kg.day] for group C and 5 mg/[kg.day] for group D) for 4 weeks. One week after treatment, the erectile function of the rats was assessed by measuring intracavernosal pressure (ICP) during electrostimulation of the cavernosal nerve. The serum testosterone (ST) levels, the percent of smooth muscle (PSM) in trabecular tissue, and the expression of mRNA and proteins of neuronal nitric oxide synthase (nNOS), inducible nitric oxide synthase (iNOS), endothelial nitric oxide synthase (eNOS) and phosphodiesterase V (PDE5) in corpus cavernosum (CC) were also evaluated.

RESULTS:

ICP, PSM, ST and the expression of nNOS, iNOS, eNOS and PDE5 were significantly decreased in group B compared with those in group A (P 0.01). However, ICP, PSM and the expression of nNOS and iNOS were increased in groups C and D compared with those in group B (P 0.05). Changes in ST and the expression of eNOS and PDE5 were not significant (P 0.05) in groups C and D compared with those in group B.

CONCLUSION:

Oral treatment with icariin ( 98.6 % purity) for 4 weeks potentially improves erectile function. This effect is correlated with an increase in PSM and the expression of certain NOS in the CC of castrated rats. These results suggest that icariin may have a therapeutic effect on erectile dysfunction.

And...


Effects of icariin on cGMP-specific PDE5 and cAMP-specific PDE4 activities.

Xin ZC, Kim EK, Lin CS, Liu WJ, Tian L, Yuan YM, Fu J.


Source

Department of Urology, the 1st Hospital, Peking University, 8 Xishiku Street, Xicheng District, Beijing 100034, China. [email protected]


Abstract

AIM:

To clarify the mechanism of the therapeutic action of icariin on erectile dysfunction (ED).

METHODS:

PDE5 was isolated from the human platelet and PDE4 from the rat liver tissue using the FPLC system (Pharmacia, Milton Keynes, UK) and the Mono Q column. The inhibitory effects of icariin on PDE5 and PDE4 activities were investigated by the two-step radioisotope procedure with [(3)H]-cGMP/[(3)H]-cAMP. Papaverine served as the control drug.

RESULTS:

Icariin and papaverine showed dose-dependent inhibitory effects on PDE5 and PDE4 activities. The IC(50) of Icariin and papaverine on PDE5 were 0.432 micromol/L and 0.680 micromol/L, respectively and those on PDE4, 73.50 micromol/L and 3.07 micromol/L, respectively. The potencies of selectivity of icariin and papaverine on PDE5 (PDE4/PDE5 of IC(50)) were 167.67 times and 4.54 times, respectively.

CONCLUSION:

Icariin is a cGMP-specific PDE5 inhibitor that may be developed into an oral effective agent for the treatment of ED.

[Ashop]

Have any of you guys used it? Since I'm younger then most men with Low T, I wanted to take a more natural route to boost libido. I have read many good reviews on HGW but I'm still skeptical.

It's an unproven herbal I would pass on. I noticed nothing from it.

[steroid.com 1]

It's an unproven herbal I would pass on. I noticed nothing from it.

^^^Did you see above?

Go to Pubmed and do some research...you may change your opinion...but it's all about the quality of what you've taken not its ability to act as a PDE5i.

[Stevens03]

I'll give L-Arginine a shot. All the review I read on HGW seem positive but I'll take your guy's word for it.

[steroid.com 1]

Also add in both:

Pycnogenol
L-Citrulline

[AaronJM1984]

I take it daily, honestly I don't notice it doing anything...just going to finish taking what I have left, probably won't purchase again.

[steroid.com 1]

^^^Agreed Aaron, I don't think you will see much of a difference (most supps don't) but it does provide an excellent base for NO2 production especailly when coupled with a good PDE5i.

[jwh7699]

I read another thread that taking 2g of L-Arginine before bed can help as a Human Growth Hormone , so if it doesn't work for you that way you have an alternative use for it.

[steroid.com 1]

^^^^Correct.

[Stevens03]

Hey, I'll take it lol.

[Stevens03]

Ok, so I just ordered some pycnogenol and l-arginine.

My question is, what is daily amount I should take of each and when should I take them. Before bed, in the morning?

[jwh7699]

"As an alternative to erectile dysfunction medicine, take arginine and pycnogenol 30 to 60 minutes before sexual activity."

http://www.livestrong.com/article/29...ne-pycnogenol/

Good Luck!!

[steroid.com 1]

I take them all 3 times a day to keep serum levels peaked...added with a good daily PDE5i and realy nice erection results.

[boxingfan30]

I took it for a while... gave me pretty bad stomach cramps.

[ZenFitness]

Stevens03, I understand the "I want to take the natural route", but in the end you are still taking something even if it doesn't come from a doctor. Additionally, most herbal supplements have far less medical research behind them. This is coming from someone who potentially jacked themselves up for a while via herbal supplements... I don't take them anymore.

You are taking something, prescription or not, but with a prescription you have the trained advice of a medical professional. My recommendation is to take this VERY seriously... I would opt towards the Cialis/Tadalafil route if you are looking for erection meds. If it is not erectile problems but instead just general libido, can I ask if you are on TRT? If it is just libido, go cruise a pool that has some nice looking women in bikinis and see if you are at all interested in seeing what is underneath the bikinis... if so, it is probably not a libido problem you are looking at but instead general anxiety or relationship problems (assuming the erections are happening).