Thread: hcg frozen
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10-31-2012, 11:30 AM #1Junior Member
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hcg frozen
Hey, so lost power due to hurricane, and put my hcg in the freezer against a bag of ice and it became frozen...I defrosted it and then injected and put it back in the freezer since we are still without power.
Is there any issue with keeping it frozen until next week?
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10-31-2012, 11:48 AM #2
no actually according to GDevine and others you can freeze hCG . they do this top prolong shelf life.
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10-31-2012, 12:32 PM #3HRT
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Freezing HCG won't hurt its potency...it's fine.
Just put it back in the fridge and use as you would.
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10-31-2012, 01:57 PM #4Junior Member
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Just to be clear, the product is hcg that is already compounded. Don't know if that changes anything...but thanks guys sounds like its ok.
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10-31-2012, 03:09 PM #5Banned
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10-31-2012, 05:40 PM #6Banned
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Yes, you can freeze it. It may damage the proteins in the hCG as shown in assays. The best way to store would be in the fridge. I have had this discussion before and stood on both ends of the discussion. Willliam Llewellyn was quoted to say that the proteins are so delicate that even the slightest bit of moisture may cause damage. I don't know what he meant by that but seemingly he is against freezing it.
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10-31-2012, 08:51 PM #7HRT
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This from one of nations leading compounding pharmacies re freezing HCG and potency:
"Attached is our potency data…originally mixed and tested in August. After testing, the preparation was frozen and stored at the lab. Every 30 days, the preparation was thawed and tested. You can see the results for up to 90 days frozen. As I’m certain your aware, the USP standard for almost all preparations is 90-110% of labeled strength, but for hCG the standard is 80-125% of labeled strength. Our results fall well within these range."
The report was confidential so it can't be posted.
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10-31-2012, 09:43 PM #8Banned
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You didn't post any data. Just a quote that I don't care about.
Look here I found one of freezing hCG too:
"Attached is our potency data...originally mixed and tested in August. After testing, the preparation was frozen and stored at the lab. Every 30 days, the preparation was thawed and tested. You can see the results for up to 90 days frozen. As I’m certain your aware, the USP standard for almost all preparations is 90-110% of labeled strength, but for hCG the standard is 80-125% of labeled strength. Our results fall short of these ranges by 40-50%."
Like I said, you can freeze it and it may damage the proteins. Best way is to store it is in the fridge as you won't subject it to a freeze thaw cycle.
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10-31-2012, 10:07 PM #9HRT
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That quote was provided by Dr. John Crisler who was looking for a new compounding pharmacy who provided him with the analysis.
You can find the thread he started on his website where he changed his mind about freezing HCG and potency degradation.
The thought process here is preloading syringes after HCG reconstitution and storing them in the freezer to be used syringe at a time as needed...not a freeze thaw cycle you mention.Last edited by steroid.com 1; 10-31-2012 at 10:12 PM.
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10-31-2012, 10:12 PM #10Banned
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I already decided, I am not stating that freezing it ruins the hCG . I am saying that it may and that the best way to store it is in the fridge, because then you aren't faced with any chance of damaging the proteins.
I don't understand the reasoning behind your rebuttal. Are you advocating freezing it rather than refrigerating it if it is going to be used within say 30 days?
Edit: A(as in one) freeze-thaw cycle would be freezing it, then thawing it for use.Last edited by Sworder; 10-31-2012 at 10:21 PM.
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10-31-2012, 10:25 PM #11HRT
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No I am not advocating freezing it; it should be refrigerated as you state.
That said, the compounding pharmacy in question here ran an analysis and discovered freezing HCG did not damage the potency of the peptide outside of the UPS standard...that's all.
Dr. Crisler has hence changed his mind based on this study that "he was all along wrong that freezing could damage the molecule".
The OP accidentally froze his HCG and I wanted to provide some data that would give him some comfort that it probably was not damaged and okay to use.
I know members who preloaded syringes and freeze them for convenience sake and they see no difference in testicle size or function.
Just tyring to help the OP is all...
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10-31-2012, 10:31 PM #12Banned
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I agree, it won't hurt the potency noticeably. I guess, I am at fault as I am very peculiar about wording
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10-31-2012, 10:36 PM #13HRT
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04-19-2013, 01:08 AM #14
Thanks for keeping thread alive
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04-19-2013, 07:10 AM #15Banned
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I wish it would of died along with the "Sworder" name. The "debate" in this thread serves no purpose other than GD's accurate explanation and informative data on freezing hCG .
But thankfully this information can be found below.
Freezing hCG
hcg frozen
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04-19-2013, 08:53 AM #16HRT
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Yea, I sort of shuddered when I saw "Sworder's" post here as well...what an ass clown he was.
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04-19-2013, 09:00 AM #17Banned
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