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  1. #1
    asiandudexxx is offline Junior Member
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    Labcorp E2 LCMS Endo Sci 500108?

    Hey all,

    Decided to finally get sensitive e2 since my old lab was only using the normal e2 test. I was planning to go to labcorp today, but when I looked at the test order form, the e2 test doesn't specify "sensitive", but isn't the standard e2 test either. On the order form, it is the only e2 test listed. The full name is Estradiol LCMS Endo Sci (test # 500108).

    From what I googled, no one can tell if this is a valid e2 test for males. Should I tell them to run test # 140244 (e2, sensitive) even though the doctor didn't make notes on the order form, or should I just get the one listed?

  2. #2
    kelkel's Avatar
    kelkel is offline HRT Specialist ~ AR-Platinum Elite-Hall of Famer ~ No Source Checks
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    You want this test:

    E Sensitive #140244. CPT code 82670

    Write them down. Keep them somewhere. Take them with you every time you go the labcorp. They are not used to doing this test and will screw it up every time if you don't.

  3. #3
    BayChamp is offline New Member
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    I discovered that LabCorp does have 4 or 5 different tests for Estradiol. I also found out that the one included in Life Extensions Male Hormone Panel does "not" include the sensitive assay.
    In order to get the sensitive assay, do you just contact Life Extension and request it? (I don't see it listed as an option on their website)

  4. #4
    kelkel's Avatar
    kelkel is offline HRT Specialist ~ AR-Platinum Elite-Hall of Famer ~ No Source Checks
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    Call them and ask. Proper codes are listed above. They are the ones you want.

  5. #5
    asiandudexxx is offline Junior Member
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    Quote Originally Posted by kelkel View Post
    You want this test:

    E Sensitive #140244. CPT code 82670

    Write them down. Keep them somewhere. Take them with you every time you go the labcorp. They are not used to doing this test and will screw it up every time if you don't.
    Thanks Kel! The lab wouldn't do any test other than the one on the form, so I'm gonna ask my doc to specifically request test # 140244 next time.

  6. #6
    berniec is offline Junior Member
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    Quote Originally Posted by kelkel View Post
    Call them and ask. Proper codes are listed above. They are the ones you want.
    maybe you can help if you are familiar with their tests. I recently had all three of their e2 tests done; two that came back with results in line with each other and on the total opposite end of the spectrum.

    Estradiol, LCMS, Endo Sci
    Labcorp test# 500108
    result: <1.0 pg/mL

    Estradiol- Roche ECLIA methodology
    Labcorp test# 004515
    result: 15.9 pg/mL

    Estradiol, Sensitive
    Labcorp Test# 140244
    result: 227 pg/mL

    so which of these am I to believe?

  7. #7
    xcraider37 is offline Associate Member
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    Quote Originally Posted by berniec View Post

    maybe you can help if you are familiar with their tests. I recently had all three of their e2 tests done; two that came back with results in line with each other and on the total opposite end of the spectrum.

    Estradiol, LCMS, Endo Sci
    Labcorp test# 500108
    result: <1.0 pg/mL

    Estradiol- Roche ECLIA methodology
    Labcorp test# 004515
    result: 15.9 pg/mL

    Estradiol, Sensitive
    Labcorp Test# 140244
    result: 227 pg/mL

    so which of these am I to believe?
    I would say something went wrong. Assuming that sensitive assay is way off. Just from my experience generally the sensitive test would be lower than the roche method. Just my opinion though.

  8. #8
    xcraider37 is offline Associate Member
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    Quote Originally Posted by BayChamp View Post
    I discovered that LabCorp does have 4 or 5 different tests for Estradiol. I also found out that the one included in Life Extensions Male Hormone Panel does "not" include the sensitive assay.
    In order to get the sensitive assay, do you just contact Life Extension and request it? (I don't see it listed as an option on their website)
    Private labs has it. They use lab corp and are the cheapest for self requesting.

  9. #9
    Lockout888 is offline Associate Member
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    Of the different testing methods Labcorp uses, the LCMS (500108, CPT Code: 82670) might be the best, and the "standard" ECLIA test (004515 CPT Code: 82670) might be the second best. The "sensitive" test (140244 CPT Code: 82670) employs the RIA method:

    RIA Direct. Itís cheap, fast, but not very accurate. Recent studies have been calling into question the use of RIA direct methodology to measure free testosterone . Unfortunately, most labs across the country only use RIA direct because of its cost effectiveness. LabCorp, the lab I used, only measures free T using RIA direct. Despite the criticisms levied at RIA direct tests, many researchers believe itís an adequate method for routine tests.

    ECLIA Method. When I tested myself for total testosterone for my experiment, the method the lab used was ECLIA, short for Electrochemiluminescent Immunoassay. Itís a fast and affordable method to measure total testosterone in your blood. Many labs use this method because itís automatic and doesnít require too much work on a lab technicianís part. However, some studies have shown that values obtained with ECLIA are significantly higher compared to the more reliable LC/MS method. Which brings me toÖ

    LC/MS Method. LC/MS is short for liquid chromatography-mass spectrometry. Itís considered the gold standard method by many researchers in measuring small molecules. Its accuracy and consistency is why the CDC is recommending LC/MS to be the standard method used when testing total testosterone. Because LC/MS is more sensitive than ECLIA, doctors typically use this method when testing patients with really low testosterone levels, such as women and children. While itís more accurate and sensitive, the LC/MS method is more expensive than ECLIA. And it takes a bit longer to get your results.

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