Thread: Estrogen metabolism
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03-25-2013, 01:35 PM #1
Estrogen metabolism
Ok so it's been my understanding that trt doesn't require an ai most of the time. So say one were to cycle and drop to trt dose, if u stop ur ai at the end if ur cycle wouldn't that create an excess in estrogen? Especially if using adex because its just an inhibitor not a destroyer?
If u drop ur test dosage say from 600mg to 150mg. Would u have to continue ai and slowly taper down till the half life brings test levels back to physiological levels and also allow the body to, I guess metabolize the excess estrogen?
-TroN-
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03-25-2013, 02:05 PM #2
Anyone?
-TroN-
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03-25-2013, 02:14 PM #3HRT
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03-25-2013, 02:24 PM #4
Are you a TRT guy doing a cycle? At any rate I will limited knowledge would say yes to all your questions.
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03-25-2013, 02:27 PM #5Originally Posted by gdevine
And I was referring to someone that's on lifelong trt but does a cycle and after his cycle back to trt. If no ai on trt were true. Is there some type of transition that has to take place to get back to that. It was just one of those things one gets curious about.
And no I didn't read that sticky. I didn't see it, I'll go to the actual website and look for it. It's hard for me to find stickies sometimes on the app.
-TroN-
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03-25-2013, 02:33 PM #6
And my apologies if u feel this is in the wrong section. I just figured it'd b the appropriate place since the objective is getting back to normal trt
-TroN-
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03-25-2013, 02:44 PM #7HRT
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Some men need an AI others don't; there are many variables that play into that and the sticky will help you understand that.
Even if a man who is "dialed in" and doesn't need an AI on physiological levels of testosterone I would imagine that increasing that dosage to levels like 600 mg/wk that it would kick start the aromatization activity and an AI would be needed.
At those levels its always E ---> T.
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03-25-2013, 02:53 PM #8Originally Posted by gdevine
Maybe I'm over thinking it?
-TroN-
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03-25-2013, 03:01 PM #9HRT
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No, you're not over thinking it...just not thinking it through.
You need to take the half life of Test Cyp into consideration when trying to estimate when Testosterone serum levels will normalize at the conclusion of the cycle.
Testosterone has a half life of about 5 to 6 days give or take.
So, if you know what your serum levels were from the time you suspended the cycle you could calculate how you body will continue to metabolize the testosterone till if settled down to normal TRT levels.
From that you can estimate how to titrate down the use of an AI.
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