Results 1 to 9 of 9

Thread: Half-Life

  1. #1
    Lockout888 is offline Associate Member
    Join Date
    Apr 2013
    Posts
    158

    Arrow Half-Life

    Why is the Half-Life of a topical like Axiron so different from an injectable like Cypionate ?

    Axiron can bump you from 300 to 650 in 2 hours, but it goes back down to 300 or so within 24 hours.

    Cypionate can do the same thing, but it takes 10 days to return to where you started?

  2. #2
    bass's Avatar
    bass is offline HRT Specialist ~ Knowledgeable Member
    Join Date
    Mar 2009
    Location
    In Southern Commiefornia
    Posts
    9,356
    gels get in your blood stream immediately, where shots have a slow release.

  3. #3
    Join Date
    Sep 2012
    Posts
    3,455
    Topicals are straight testosterone without an ester attached. Testosterone has a half-life of something like 10-100 minutes.

    Testosterone cypionate has an ester attached to the testosterone. It takes time for you body (liver I think) to cleave the ester off the testosterone molecule. Hence the long half-life.

  4. #4
    kelkel's Avatar
    kelkel is offline HRT Specialist ~ AR-Platinum Elite-Hall of Famer ~ No Source Checks
    Join Date
    Sep 2010
    Location
    East Coast Dungeon
    Posts
    28,936
    The purpose of the quick response to gels is to mimick the bodies natural rise and fall (diurnal) of endogenous testosterone . Closest thing to "natural" we have but it's a pain in the ars.....some do great on it though!
    -*- NO SOURCE CHECKS -*-

  5. #5
    Lockout888 is offline Associate Member
    Join Date
    Apr 2013
    Posts
    158
    Quote Originally Posted by kelkel View Post
    The purpose of the quick response to gels is to mimick the bodies natural rise and fall (diurnal) of endogenous testosterone. Closest thing to "natural" we have but it's a pain in the ars.....some do great on it though!
    What does a normal (non-hypogonadal) rise & fall look like as far as numbers?

  6. #6
    Join Date
    Sep 2012
    Posts
    3,455
    Quote Originally Posted by Lockout888 View Post
    What does a normal (non-hypogonadal) rise & fall look like as far as numbers?
    see the attached chart:Half-Life-testosterone-level.gif

  7. #7
    Lockout888 is offline Associate Member
    Join Date
    Apr 2013
    Posts
    158
    Quote Originally Posted by The Deadlifting Dog View Post
    see the attached chart:
    So normal levels naturally rise about 400 ng/dl each day and then fall?

  8. #8
    Join Date
    Sep 2012
    Posts
    3,455
    Yes.

  9. #9
    xcraider37 is offline Associate Member
    Join Date
    Jun 2012
    Posts
    417
    Quote Originally Posted by The Deadlifting Dog View Post
    Yes.
    Was going to comment on the chart you posted, but now that I look at it more closely, I have no comment, please disregard.
    Last edited by xcraider37; 05-21-2013 at 02:34 PM.

Thread Information

Users Browsing this Thread

There are currently 1 users browsing this thread. (0 members and 1 guests)

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •