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Thread: What happens when natural testosterone production is shut down?

  1. #1
    VenicePump is offline Associate Member
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    What happens when natural testosterone production is shut down?

    I am just curious what happens when your natural testosterone production shuts down. Do you know when it happens... I would imagine the external testosterone keeps you going, but sex drive might not be there (not able to get erection)?

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    poison is offline Junior Member
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    Google Low T

    /e: do you mean while you're cycling? If you're giving your body an exogenous source of test, then that's a different story.

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    VenicePump is offline Associate Member
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    Quote Originally Posted by poison View Post
    Google Low T

    /e: do you mean while you're cycling? If you're giving your body an exogenous source of test, then that's a different story.
    I see, so HCG should only be used during or after cycle? Some people say to use it while on cycle..

    I am on TRT as well, so I am able to keep external test in my body all year around.

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    Vettester is offline Banned
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    ?? Not sure what exactly you mean. By "external", are you meaning exogenous? If so, why would you think libido would be diminished? Please clarify your thread, thanks.

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    VenicePump is offline Associate Member
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    Quote Originally Posted by Vettester View Post
    ?? Not sure what exactly you mean. By "external", are you meaning exogenous? If so, why would you think libido would be diminished? Please clarify your thread, thanks.
    Yes sir you are correct I meant to say exogenous. I was thinking since taking testosterone injections it would suppress my natural production. Therefore I would need to keep HCG in me as well to keep my natural production going. Or will the exogenous test I am injecting keep my testicles from shrinking and etc since I am taking it once per week?

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    Exogenous test will shut you down eventually. You'll know when its happening... Your testicles will hug your body like they did when you were 5 IE they will atrophy and ascend. I personally am not an HRT.patient but I take HCG while on cycle and it does keep them hanging low.

    Blood tests really are the best indicator - FSH/LH will be suppressed when you're shut down and normalize when HCG is doing its job.

    My personal sweet spot seems to be 200iu every 2 to 3 days but that's a highly individual thing. I'm still experimenting with optional dose and frequency.

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    VenicePump is offline Associate Member
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    Quote Originally Posted by Java Man View Post
    Exogenous test will shut you down eventually. You'll know when its happening... Your testicles will hug your body like they did when you were 5 IE they will atrophy and ascend. I personally am not an HRT.patient but I take HCG while on cycle and it does keep them hanging low.

    Blood tests really are the best indicator - FSH/LH will be suppressed when you're shut down and normalize when HCG is doing its job.

    My personal sweet spot seems to be 200iu every 2 to 3 days but that's a highly individual thing. I'm still experimenting with optional dose and frequency.
    I been taking test for awhile now and my testes look fine. I feel fine as well. However I agree with what your saying. I just sent doc an email to see what he says just to be safe.
    Last edited by VenicePump; 05-30-2013 at 02:37 AM.

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    Java Man's Avatar
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    Get your FSH and LH tested. I'd wait to hear more from some of the HRT experts. I'm just giving you my personal experience, so its not based on hearsay or 'broscience' but I have no formal medical training.

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    Quote Originally Posted by VenicePump View Post
    I been taking test for awhile now and my testes look fine. I feel fine as well. However I agree with what your saying. I just sent doc an email to see what he says just to be safe.
    Read this http://forums.steroid.com/hormone-re...ould-know.html

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    @java hcg mimics lh, i dont tthink lh and fsh normalize...since hcg only acts like them and doesnt promote them.

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    Quote Originally Posted by powerlifterty16 View Post
    @java hcg mimics lh, i dont tthink lh and fsh normalize...since hcg only acts like them and doesnt promote them.
    That's right. It's my understanding that once you introduce exogenous testosterone , the pituitary senses enough T is in you bloodstream and stops LH secretion. That's why we take hCG . Exogenous T shuts down the HPTA. If you don't take hCG, eventually your stones will get smaller and will cease to produce endogenous T.

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    And you can't stay on hcg all the time, could possibly desensitize your LH receptors. But it's a must do when needed protocol when on long time tes injections. Blood work will tell you how often a year you need to use it, but your body will def let you know!

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    Quote Originally Posted by tectime View Post
    And you can't stay on hcg all the time, could possibly desensitize your LH receptors. But it's a must do when needed protocol when on long time tes injections. Blood work will tell you how often a year you need to use it, but your body will def let you know!
    I'd like to know where you got your information regarding hCG . Your first two sentences seem to contradict each other. Can you clarify what you mean?

    Many on this forum inject hCG daily over decades. To my knowledge - and this has been cited often; Dr. John Crisler for one - only doses over 500iu per day have the possibility of desensitizing the Leydig cells of the testes. Please cite the sources for your comments. Thanks.
    Last edited by 2Sox; 05-30-2013 at 08:35 AM.

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    My doctor who prescribes my hrt ! I've been doing it this way for about 4 yrs with no problems. What I mean is a must do is you need it to restore your own production, you should not do it all the time, you can google hcg and read that it may desensitize LH receptors in probly every article. So you need it but not all the time. I know people that shoot 600/800 mg of juice a wk for a year, doesn't make it the right way! And dude my doc
    isn't a gp, this guy specializes in hormone replacement. And he's super cool ex bodybuilder friend of mine, so I can call him a midnight if I got a thought, oh and our families vac together. Starting to get the picture of how I ge my info, plus if I could show you before and after pics you'd see knowledge used properly! And dude I've shut my self down on tren , on massive doses of tes/ deca , and I've always been able to recover every time, blood work every 3 months, so I know what works great for me and man I'm 51 years old and been playing this game off and on since age 27.

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    And dude you shouldn't be rude! You should question, that's how we learn, but no need to be rude dude ! Haha haha

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    Quote Originally Posted by tectime View Post
    And dude you shouldn't be rude! You should question, that's how we learn, but no need to be rude dude ! Haha haha
    He wasn't being rude at all.
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    I just want to address the OP's question on libido with exogenous test and natty test from testes. Test is a big factor on libido for guys, and it doesn't matter if test we inject or if it's test we create naturally. As long as there is enough test in our body's to generate libido (there's a better way to word that but only had 1 cup of coffee) then we will have. That being said also remember that test is only one component of libido so if that becomes a problem you need to look at all factors and evaluate. So you can tell by the physical size and characteristics of your testicles when they begin shutting down, but I don't think you will "feel" them shutting down by using your libido as the measuring stick.

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    Oh dude I was just messing with him! Hence the haha at the end of sentence. I love it when someone asks that exact question on how I get info. You know kinda like showing your buddy your new custom Harley!

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    Quote Originally Posted by tectime View Post
    And dude you shouldn't be rude! You should question, that's how we learn, but no need to be rude dude ! Haha haha
    Being rude was not my intention. (I won't call you dude, although it rhymes. I wouldn't feel I was being respectful.)

    Maybe you should place your comments on the Anabolic Steroids section of this forum. IMO, your comments are not relevant to those of us on a steady protocol of TRT. Most are not shooting massive doses of anything. We are just on TRT. We are looking for answers and hope other people's experiences and knowledge will help us make decisions to improve our quality of life. Sources that come from opinions or personal experience should be stated as such. They are often very useful, as are yours. But if a poster's sources are not cited, they often confuse or mislead - even though this may not be the intention of the poster.
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    Dude I said was messing with you! I didn't feel you where truly being rude . And to clarify I no longer inject massive doses either, but that shows the power of hcg to restart you, if it will restart that it will help any hrt participant. And man did you read info comes from an hrt specialist, you think that might go well in an hrt forum. I find useful info in here alot, mainly from others experience, dude this is a chemistry experience every time anyone starts hrt. It takes time to get your protocol correct.

  21. #21
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    Oh and about the dude, did not mean to offend ! It's like saying bro or brother to me, as I don't like to use the term brother or bro unless by blood or Personal bond that relationship exists. That's real tight for me ! But again just the way I talk ! No offense meant!

  22. #22
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    Quote Originally Posted by tectime View Post
    Oh and about the dude, did not mean to offend ! It's like saying bro or brother to me, as I don't like to use the term brother or bro unless by blood or Personal bond that relationship exists. That's real tight for me ! But again just the way I talk ! No offense meant!
    Thanks for the clarification on that.

    It's my understanding that if you are ON TRT, hCG doesn't "restart" anybody. It just mimics LH and fools your stones into producing T. That's the main job of hCG. From my knowledge, some men can function on hCG alone without T. (Shippen writes of this and I believe also does Morganthaler.) I don't know how long this can last. If you are hypogonadal, you'll eventually need exogenous T to maintain adequate levels. If you are on TRT - your HPTA is essentially shut down. Period. Unless I am terribly mistaken, nobody "restarts" while on TRT. It's a physiological impossibility.
    Last edited by 2Sox; 05-30-2013 at 11:15 AM.

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    Oh man I promise whether you want to call it restart, replenish, whatever hcg will increase testes size, clear out your hpt axils, increase volume of semen everything it takes to bring your nat. levels up to par. True you are about long term tes usage it will definitely turn down your own system, but that is not the same as total shutdown. That's why for me I only need to do a 10 wk 500iu every 3.5 days cycle about every 8 to 9 months. Also my tes level goes up dramatically when on that cycle due to my nat. Tes level increasing! Bloods show nat increase every time, and yes I do bloods Pre and bloods post, every time.

  24. #24
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    Quote Originally Posted by tectime View Post
    Oh man I promise whether you want to call it restart, replenish, whatever hcg will increase testes size, clear out your hpt axils, increase volume of semen everything it takes to bring your nat. levels up to par. True you are about long term tes usage it will definitely turn down your own system, but that is not the same as total shutdown. That's why for me I only need to do a 10 wk 500iu every 3.5 days cycle about every 8 to 9 months. Also my tes level goes up dramatically when on that cycle due to my nat. Tes level increasing! Bloods show nat increase every time, and yes I do bloods Pre and bloods post, every time.
    I have to ask, is English your first language?

    And a few points I think are worth elucidating, given the assumptions of HCG relevant in this thread.

    First, HCG alone does not "clear out" your HPTA - it simply is the LH analog stimulating testicular testosterone , androstenedione, and dehydroepiandrosterone (DHEA) production via the Leydig Cells. Even when TRT (a potential form of male contraception) is accompanied with HCG, spermatogenous often decreases or can even cease all together. HCG is no guarantee in keeping fertility. It is worth noting that HCG does help preserve spermatogenous, but does so by not direct functional means as often ascertained. Let's explore a bit further by what I mean.

    The principal reason why your testes do not atrophy when using HCG is due to stimulated androgen production and not sperm production -- I think it important to make that point clear. Sperm production takes place in the sertoli cells, activated by follicle-stimulating hormone (FSH). The exogenous equivalent analog to FSH is Human Menopausal Gonadotrophin (HMG), which is considerably more expensive and not as readily accessible. Hence, HCG is the more practice drug to prescribe, despite the concomitant or less-efficient stimulation instead of direct means.

    Lastly, I'll mention that your testosterone levels increase from HCG not because of positive feedback within the hypothalamic–pituitary–gonadal axis, but simple stimulated production in by the Leydig cells, as previously mentioned. Whenever exogenous testosterone is introduced in the body, you're effectively suppressing your HPTA. As the adage goes, you can't have your cake and eat it too.
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    Why would you ask about English as first language? It is although I can speak and understand two more. Also dude are you a doctor or a fat ass that googles info all day! I get my info from a DOCTOR ! With years of specializing in hormone replacement . I'm living proof that it works ! Are you or are you some dude sitting behind a screen. You and I have danced this dance already! Again is my grammar, punctuation, what not suitable for you! I did only attend college for 4 years, but really my info is first hand from a DOCTOR ! So really dude !

  26. #26
    Vettester is offline Banned
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    Tectime, you mentioned that you cycle HCG . What do you do in between the cycles to keep your serum levels elevated? Your HPTA is suppressed, so you would basically drop to baseline in approx 3 weeks (give or take).

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    no need for calling people a fat ass... really not the place for this.
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    Vet, man I'm not the doc but I'm headed to the gym in afew to workout with him so I'll ask. I follow the protocol he puts me on and man for real I do bloods every three or four months depending if out of state right on 3 month mark, so he tells me when unless I see any signs I need it. As long as I stick to the protocol he had me on, it's all good. He's tells me the numbers, shows my the papers, and we go from there. I believe for me once I get my nat. levels up, they stay up for a while before any signs of shutdown appear again either in bloods, or physical signs.
    Now remember I said I do bloops every three months, I see my doctor every week at the gym, once a month at his office, and I live a very healthy and stress free life. All contributing factors to a males health.

  29. #29
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    Quote Originally Posted by tectime
    Vet, man I'm not the doc but I'm headed to the gym in afew to workout with him so I'll ask. I follow the protocol he puts me on and man for real I do bloods every three or four months depending if out of state right on 3 month mark, so he tells me when unless I see any signs I need it. As long as I stick to the protocol he had me on, it's all good. He's tells me the numbers, shows my the papers, and we go from there. I believe for me once I get my nat. levels up, they stay up for a while before any signs of shutdown appear again either in bloods, or physical signs.
    Now remember I said I do bloops every three months, I see my doctor every week at the gym, once a month at his office, and I live a very healthy and stress free life. All contributing factors to a males health.
    Has me on not had me on trying to finish too fast so I can get to gym. Really I don't put any of this out as my opinion, but as info gathered from a doctor, not everyone's the same I know for me it works great!
    Attached Thumbnails Attached Thumbnails What happens when natural testosterone production is shut down?-image-2110100660.jpg   What happens when natural testosterone production is shut down?-image-3286105575.jpg  

  30. #30
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    Quote Originally Posted by phaedo View Post
    I have to ask, is English your first language?

    And a few points I think are worth elucidating, given the assumptions of HCG relevant in this thread.

    First, HCG alone does not "clear out" your HPTA - it simply is the LH analog stimulating testicular testosterone , androstenedione, and dehydroepiandrosterone (DHEA) production via the Leydig Cells. Even when TRT (a potential form of male contraception) is accompanied with HCG, spermatogenous often decreases or can even cease all together. HCG is no guarantee in keeping fertility. It is worth noting that HCG does help preserve spermatogenous, but does so by not direct functional means as often ascertained. Let's explore a bit further by what I mean.

    The principal reason why your testes do not atrophy when using HCG is due to stimulated androgen production and not sperm production -- I think it important to make that point clear. Sperm production takes place in the sertoli cells, activated by follicle-stimulating hormone (FSH). The exogenous equivalent analog to FSH is Human Menopausal Gonadotrophin (HMG), which is considerably more expensive and not as readily accessible. Hence, HCG is the more practice drug to prescribe, despite the concomitant or less-efficient stimulation instead of direct means.

    Lastly, I'll mention that your testosterone levels increase from HCG not because of positive feedback within the hypothalamic–pituitary–gonadal axis, but simple stimulated production in by the Leydig cells, as previously mentioned. Whenever exogenous testosterone is introduced in the body, you're effectively suppressing your HPTA. As the adage goes, you can't have your cake and eat it too.
    Thank you for this extremely clear explanation. And I learned something I hadn't known regarding HMG and sperm production.

  31. #31
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    Tectime, thanks for the pics. Now I know why you say dude!
    Your a surfer and in my book that's cool. ...........gotta lighten this thread up a little

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    Cool Cten! I see your a contractor, cool I'm an industrial contractor myself, you know refineries, power plants, chem plants. The beach life is my off time gig! But thanks for the positive! It helps all to a better state in life ! Right ! Hey man keep up that active lifestyle your profile shows way to live ! ???

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    Quote Originally Posted by tectime View Post
    Cool Cten! I see your a contractor, cool I'm an industrial contractor myself, you know refineries, power plants, chem plants. The beach life is my off time gig! But thanks for the positive! It helps all to a better state in life ! Right ! Hey man keep up that active lifestyle your profile shows way to live ! ???
    Will do....Dude!

  34. #34
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    Question

    Speaking of hmg, I see there's an increased risk of miscarriage when women use it. Any similar dangers if its the male that's taking it?

    webmd.com/a-to-z-guides/gonadotropin-treatment-for-infertility

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