Anastrozole dosage

[Lockout888]

So about a month ago, my TT was still on the lower end and my Doctor bumped my dosage to 150mg per week. He wanted me to see how I felt and get new labs after a month. I didn't feel much different than when on 100mg per week, and the new labs show my TT didn't go up much. I must be aromatizing more?

Previous Protocol: Test Cyp 100mg 1x week, HCG 250iu 3x week, Anastrozole .25mg on day after T injection.
Labs (7/23/13) on day 6 after test injection:
Total Test = 597 (348-1197)
Estradiol = 29.4 (7.6-42.6)

Current protocol (last 5 weeks): Test Cyp 150mg 1x week, HCG 250iu 3x week, Anastrozole .25mg day after T injection.
New Labs (9/4/13) 7 days after test injection:
Total Test = 586 (348-1197)
Estradiol = 44.3 (7.6-42.6)

My Doctor wants me to increase my Anastrozole dosage to .5mg per week.

Which would be better?
* Take .5mg day after test injection
* Take .25mg day after test injection, and another .25mg 2 days later

[jimmyinkedup]

I would split the dosage....

[bass]

your e2 is not terribly high, maybe consider supplementing with zinc instead of adding more drugs into your system. and if you split your dose as Jimmy suggested you'll have even less E2 conversion.

[kelkel]

What's your free T level? SHBG too?

[FRDave]

If you went back to the 100mg dose and injected twice per week at 50mg every 3.5 days, you would probably be looking pretty good and not even need an AI. Maybe zinc/DIM at the most.

Food for thought if your Dr. is open for suggestions.

[bullshark99]

Yeah, a tad high but that's about my comfort zone. I would split the dosage.

[Lockout888]

What's your free T level? SHBG too?

Did not get SHBG tested this time. Most recent was 2 months ago:

Labs (7/5/13) on day 2, 36 hours after test injection:
Total Test = 591 (348-1197)
Estradiol = 25.3 (7.6-42.6)
Albumin = 4.4 (3.5-5.5)
SHBG = 15.4 (16.5-55.9)
Free T = 17.7 ng/dL = 2.99 %
Bio T = 424 ng/dL = 71.7 %

[EverettCD]

I agree with the knowledgeable guy's above, I would split the dose.

When I started Test Cyp (prior to TestC I was using topicals unsuccessfully) I started with 70mg Test Cyp injections twice per week (Monday AM & Thursday PM) & so far so good, I feel much better these past 3 weeks or so. I am hoping after I have BW done in a couple weeks that I will not have a need for an AI. I did get restless one night & purchased some Arimidex to have on hand if needed, thankfully I haven't felt any high E2 signs/symptoms as of yet, BW will lead me down that path.

How are your family jewels hanging these days after being on Test for a while? Do you feel your using enough HCG ? For ME I need a minimum of 1000iu per week (I inject 150iu every morning). BUT, that is the HCG dosage that works for ME, if you're good to go on your current dosage great. I wouldn't mind less injections per week.

[Lockout888]

How are your family jewels hanging these days after being on Test for a while? Do you feel your using enough HCG? For ME I need a minimum of 1000iu per week (I inject 150iu every morning). BUT, that is the HCG dosage that works for ME, if you're good to go on your current dosage great. I wouldn't mind less injections per week.

I still get the occasional ache down there, and size is about 75% of what they once were. How did you determine what HCG dose works for you?

[FRDave]

I still get the occasional ache down there, and size is about 75% of what they once were. How did you determine what HCG dose works for you?

Trial and error. Try 300iu and see how you feel. I use to do 250 3x a week and recently changed it up to 400iu twice a week out of convenience. The boys are larger and my E2 dropped quite a bit. I am now able to use less arimidex , hoping to get off completely. Never have any ache :-)

Some need as little as 500iu weekly, where as others need up to 1000iu weekly. Just try to stay under 500iu in a single dose.

[kelkel]

Did not get SHBG tested this time. Most recent was 2 months ago:

Labs (7/5/13) on day 2, 36 hours after test injection:
Total Test = 591 (348-1197)
Estradiol = 25.3 (7.6-42.6)
Albumin = 4.4 (3.5-5.5)
SHBG = 15.4 (16.5-55.9)
Free T = 17.7 ng/dL = 2.99 %
Bio T = 424 ng/dL = 71.7 %

Free T looks great here. SHBG borderline low but there's really not much you can do with that. Whatever path you take make only one change at a time. Otherwise you won't know what is working for you.

[EverettCD]

I still get the occasional ache down there, and size is about 75% of what they once were. How did you determine what HCG dose works for you?

If the physical size of your testicles is back to pre-TRT size or fairly close to it. Also checking sperm count.

My Doc got the paperwork from my PCP that did a sperm count pre-TRT. He then check sperm count pre-HCG , then he was going to check sperm count again a couple of months later but that's when my wife told me the best news I could ever hear. She's currently pregnant. Conception happened about 2 months after starting HCG. I couldn't find my copy from my pre-HCG sperm count but it was drastically lower than my pre-TRT sperm count. I know my production wan't 100% shut down, but it was damn near.

Do you plan on fathering children in the future?

[EverettCD]

Trial and error. Try 300iu and see how you feel. I use to do 250 3x a week and recently changed it up to 400iu twice a week out of convenience. The boys are larger and my E2 dropped quite a bit. I am now able to use less arimidex , hoping to get off completely. Never have any ache :-)

Some need as little as 500iu weekly, where as others need up to 1000iu weekly. Just try to stay under 500iu in a single dose.

Dave

You say your E2 dropped & the only part of your protocol you change was the increase of HCG to 400iu twice per week? If I'm reading this correctly that's good news. Maybe something I try if my BW comes back with elevated E2.

How much were you able to lower your Arimidex dosage? Dex dosage timing?

[FRDave]

Dave

You say your E2 dropped & the only part of your protocol you change was the increase of HCG to 400iu twice per week? If I'm reading this correctly that's good news. Maybe something I try if my BW comes back with elevated E2.

How much were you able to lower your Arimidex dosage? Dex dosage timing?

Correct. Before I was using 250iu every Mon / Wed / Fri for a total of 750iu weekly. With test at 40mg on Tues night and Sat morning for a total of 80mg weekly, I was using .75mg arimidex the day after my test injections.

Now I am using 400iu the day before my test injections for a total of 800iu weekly and was able to drop my arimidex to .5mg the day after test injections.

Still a bit high on the arimidex but it's better than before.

[EverettCD]

Sounds good to me. I'm all for less medication. It just seemed weird to me that two larger doses of HCG instead of 3 smaller doses lowered your E2. I have read so many posts about larger HCG doses causing E2 levels to go up. I know the doses we take aren't considered "really high" for the most part. But obviously this works for you, something for me to keep in mind. Thanks for the info.

[FRDave]

Sounds good to me. I'm all for less medication. It just seemed weird to me that two larger doses of HCG instead of 3 smaller doses lowered your E2. I have read so many posts about larger HCG doses causing E2 levels to go up. I know the doses we take aren't considered "really high" for the most part. But obviously this works for you, something for me to keep in mind. Thanks for the info.

I was surprised as well, this is why I was doing the 3 smaller doses to begin with, thinking my E2 would be lower.

[EverettCD]

I was surprised as well, this is why I was doing the 3 smaller doses to begin with, thinking my E2 would be lower.

That is one of the main reasons I have been injecting 150iu per day. After my BW coming up in a couple weeks I'll try 500iu twice per week & see how it effects my E2 levels. If I need to start Airimidex due to elevated E2 I'll wait to experiment with the HCG dose later after getting dialed in, I'll cross that bridge when I get to it.