Dr.CRISLER ClomiD CHALLENGE

[jomamma007]

Hey guys,
Being only 22 I don't really want to be on trt forever at this age. Last time I tried a restart my numbers held for 2 months then crashed. Clomid makes me feel like crap but I believe it's because I have too much estrogen on it, according to blood work(although it wasn't a sensitive panel). Anyways I'm thinking about trying this as per Dr.Crisler's instructions on his forum.

Here's how you do it:

Start at 12.5mgs Clomid per day. After 3 weeks, run these labs (which you ran before you started, BTW):

TT
LH
FSH
SHBG
E2 (sensitive only)

If you feel much better--the goal of therapy--you are all set. Even if your T levels don't look great; that would mean you happened to catch your new production level at a trough.

If you don't feel much better, have your LH and FSH levels risen substantially? If not, increase the dose to 25mgs. A couple weeks later, the same labs again. You can go to 37.5mgs, then 50mg per day if necessary. Notice we are employing 1/4 tab increases, for convenience.

If LH/FSH rose substantially, and T did not, and you still don't feel well, look to testicular failure as your issue.

Of note, some have gotten great results on only 12.5mgs every other day.

If your T rose nicely, but SHBG also shot up, this counteracts the benefit. The estrogen half of the SERM-class drug did that. Try some Danazol, 50mg per day, oral, to try to lower SHBG.

If E shot up, add anastrazole, starting at 0.25mg every other day, and increase as necessary. Remember, it takes several weeks for E and SHBG to restabilize (SHBG may lower with the E).

Using this protocol can help you avoid going on frank TRT. That would be a good thing.

Now my hopes that running this for say 4-6 months and then getting off would give my body long enough to recover it's own levels as I don't want to be on any hrt program, but at least with clomid it's my own boys making my test.

He also said Nolva can be used instead..

[PJS19]

Interesting. Im also 22 trying something similar. Clomid 25mg eod.

I wonder if using nolva would be a better option. I thought it didnt act at the hypothamlus and therefor wasnt as good for restarts? Any more info on nolva in restarts? I might use both

[dreadnok89]

That's a lot of chlomid at 50 a day.

[jomamma007]

Well you start at 12.5 and titrate up slowly if needed.

[dreadnok89]

Joe, am I wrong tho? Is 50 a lot? I heard it has side effects and I hear novadex has really none

[jasondd1]

I tried clomid eod at 25 mg and after 6 weeks had to quit because it crashed my progesterone and I couldn't sleep. It did raise total from 300 to 670 but did nothing on free and my e2 stayed at 11. If cloimid doesnt work for you i like the idea of trying nolva

[jomamma007]

they both have side effects, and both can elevate SHBG and nolvadex lowers IGF as well.
50 is probably the highest dosage one would want to take.