6 Week Blood Work is IN! Please help!

[LFH40]

Hi guys,
I'm attaching my 6 week blood work. Initial bloods showed 433 total test and 6.8 free.

Below are my brand new results. I'm worried about the E2. I'm already on zinc and DIM. Need an AI for this?

Thanks for whatever support you can give, guys.
I'm with the site sponsor, FYI...

[dreadnok89]

Yo lf, I think esyradiol always tests higher than sensitive assay.

[LFH40]

Yo lf, I think esyradiol always tests higher than sensitive assay.

I appreciate your reply, but I am not sure I understand your reply.

[APIs]

Yo lf, I think esyradiol always tests higher than sensitive assay.

He did have the sensitive test unless I'm mistaken? The ranges for non-sensitive are much broader...

[LFH40]

I wasn't sure how to properly read the results so above is the actual screen shot of my results. Just wondering if I should contact the Dr about an AI or is this something I don't worry about. I feel decent. Better than pre-TRT, however I still have major nipple sensitivity and they're always hard.

I want to make the most of my newly increased free test. It about tripled from pre-TRT. Just wanna make sure it's being utilized.

[xcraider37]

He did have the sensitive test unless I'm mistaken? The ranges for non-sensitive are much broader...

No that was not the sensitive test, that was the standard labcorp ranges, he is probably running high on estradiol, but would be nice to see a sensitive assay. OP any symptoms of high E2?

[LFH40]

No that was not the sensitive test, that was the standard labcorp ranges, he is probably running high on estradiol, but would be nice to see a sensitive assay. OP any symptoms of high E2?

I've got the nipple sensitivity and embarrassingly, my nipples are always hard. I actually spoke with the Doctor about 10 minutes ago and he's going to review my hard copy results and call me back. He said he's going to put me on anastrozole, 1/2 tablet twice a week, three days apart from each dose. He said that would bring me down into 20-30 range. He said 65.8 is too high.

From your standpoint, guys, are any of you on 1/2 tablet twice a week? I know it's a fine line between finding the sweet spot, being to high and crashing out your E2. I'm trying to avoid that. I've never been optimal with my testosterone in my life. I've got 870 now. My highest I ever was, was back when they discovered my pituitary tumor originally back in 1993 when I was 20 years old and it was a 773. I'm assuming I've been on the decline ever since. The lowest I've been tested was in September and it was a whopping 192. So being at an 870 is great and free test of 21.3, but if the E2 is just simply too high, I'm sure I'm not getting the maximum benefit of all this testosterone. Morning erections are getting a bit better. A few spontaneous erections sprinkled in here and there (meaning no manual stimulation, just based purely off of thoughts. The libido is a bit better. It's ALL better than it originally WAS, but I am sure I'm not back to "normal" after only 6-7 weeks on TRT.

Man, you guys are just great with all the help. As you know, it's a sensitive topic and I can't really discuss this with most people as they aren't educated on the matter. My wife is supportive, however what she knows about it is only what I tell her about it, and I'm still learning myself. Just want to get "dialed in" as they say.

[xcraider37]

I've got the nipple sensitivity and embarrassingly, my nipples are always hard. I actually spoke with the Doctor about 10 minutes ago and he's going to review my hard copy results and call me back. He said he's going to put me on anastrozole, 1/2 tablet twice a week, three days apart from each dose. He said that would bring me down into 20-30 range. He said 65.8 is too high.

From your standpoint, guys, are any of you on 1/2 tablet twice a week? I know it's a fine line between finding the sweet spot, being to high and crashing out your E2. I'm trying to avoid that. I've never been optimal with my testosterone in my life. I've got 870 now. My highest I ever was, was back when they discovered my pituitary tumor originally back in 1993 when I was 20 years old and it was a 773. I'm assuming I've been on the decline ever since. The lowest I've been tested was in September and it was a whopping 192. So being at an 870 is great and free test of 21.3, but if the E2 is just simply too high, I'm sure I'm not getting the maximum benefit of all this testosterone. Morning erections are getting a bit better. A few spontaneous erections sprinkled in here and there (meaning no manual stimulation, just based purely off of thoughts. The libido is a bit better. It's ALL better than it originally WAS, but I am sure I'm not back to "normal" after only 6-7 weeks on TRT.

Man, you guys are just great with all the help. As you know, it's a sensitive topic and I can't really discuss this with most people as they aren't educated on the matter. My wife is supportive, however what she knows about it is only what I tell her about it, and I'm still learning myself. Just want to get "dialed in" as they say.

Don't do a 1/2 tab 2x per week, on your own no need to tell your doctor, start with .25 2x per week. .50 will probably crash you trust me adex is very strong.

[Machdiesel]

What's your protocol? 50mg 2x a week?

[LFH40]

What's your protocol? 50mg 2x a week?

Yes, 50mg 2x per week and 250iu hcg twice a week as well.

[Brett N]

I am on the same protocol and I started 1/4 x 2 a week of anastrozole and that had my numbers too low. I ended up tasking 1/4mg (tab) once a week and doing great now.

Not sure on my feelings about not telling doc but 1/2 x 2 seems like an extreme amount.

[bass]

sensitive assay range is 3-70, and the one you got its not. I've seen some member do side by side comparison where its shows higher numbers on a standard test and lower number on the sensitive assay. so you may be okay but to be sure you need to order the sensitive assay. do the blood test your self if you need to, don't wait for the doc.

[Machdiesel]

^ I'm also on the same protocol and feeling symptoms of high E. Doc seems against an AI so hoping I'm out of range and he's forced. Getting tests back tomorrow. I'm gonna try and talk him into exemestane and do 6.25 EOD

[LFH40]

sensitive assay range is 3-70, and the one you got its not. I've seen some member do side by side comparison where its shows higher numbers on a standard test and lower number on the sensitive assay. so you may be okay but to be sure you need to order the sensitive assay. do the blood test your self if you need to, don't wait for the doc.

You would think that going with the site sponsor you would get the sensitive assay test. I'm so confused now. The Dr from LowT is prescribing me 1/2 pill twice a week which would be too much and crash me, and 1/4 tablet twice a week would also bring it low? I feel odd about not telling the doctor, because already I had him switch me from one test shot per week to 2x per week. Do the site sponsor dr's still have some things to learn? I am happy my test is going up, but nervous about crashing the E2. More confused now than when I first posted my thread. Ugh

[dreadnok89]

not every doctor is sold on the sensitive E test. are you tired for no reason at all? or do you start tearing up watching tv? or do you have hot flashes?

[kelkel]

Don't do .5mg x 2 per week for more than about a week, IMHO. Odds are you'll eventually crash at that level. Consider 1mg of adex per week is about what most guys on a 500mg per week cycle use (.25mg EOD.) I'd bring your concerns up to your doc and work through it with him. I could not imagine needing more than .25 the day after each injection, if that. Repeated blood work is key here. Let the doc know you want to test again in another 4 weeks after you change your protocol and ask for the sensitive assay.

The non-sensitive assay is cheaper BTW and many doc's will say it's only about a 3% deviation from the sensitive assay. I have not been persuaded to agree with that just yet. Although as astute doc should be able to get by with either.

[Machdiesel]

What's your recommendation for Exemestane as a starting point?

[kelkel]

Pharmacokinetics and Dose Finding of a Potent Aromatase Inhibitor, Aromasin (Exemestane), in Young Males

[Machdiesel]

Ok I'm retarded and prob have more questions then before but it seems someone could take 25mg a day and not crush their E2, yet the recommendations for TRT are very low, like 25mg a week I divided dosages

Not being lazy really tried to read it but p-90/ 45% +- 26 etc Etc I have no idea how much it decreased. Going by the chart estradiol only dropped 10 points on 25mg a day?

[LFH40]

Don't do .5mg x 2 per week for more than about a week, IMHO. Odds are you'll eventually crash at that level. Consider 1mg of adex per week is about what most guys on a 500mg per week cycle use (.25mg EOD.) I'd bring your concerns up to your doc and work through it with him. I could not imagine needing more than .25 the day after each injection, if that. Repeated blood work is key here. Let the doc know you want to test again in another 4 weeks after you change your protocol and ask for the sensitive assay.

The non-sensitive assay is cheaper BTW and many doc's will say it's only about a 3% deviation from the sensitive assay. I have not been persuaded to agree with that just yet. Although as astute doc should be able to get by with either.

Very well put, just need to figure out a tactful way to put it to the doctor so I don't offend him. I'm with lowT dot com and I don't want to get run out of there for pissing off the doctor. He told me I could do my own independent estradiol test in a month seeing as though the site sponsor doesn't have another blood test till my 6 month labs. I am very inclined to use .25 after each of my twice a week injections. I would hate to do something without doctor approval, especially when it's a doctor who is up on correct protocol, but it's been so long since I felt good that I don't want to crash my E2 and ruin what I have going so far.

[dreadnok89]

Exestamane and arimidex are different. Exestamane is more expensive. I believe that's the reason everyone tlgets it

[Machdiesel]

I've seen EOD is acceptable , some say ED. It comes in 25mg pills so seems 6.25(1/4 pull Ed) seems like a reasonable starting point

[xcraider37]

Very well put, just need to figure out a tactful way to put it to the doctor so I don't offend him. I'm with lowT dot com and I don't want to get run out of there for pissing off the doctor. He told me I could do my own independent estradiol test in a month seeing as though the site sponsor doesn't have another blood test till my 6 month labs. I am very inclined to use .25 after each of my twice a week injections. I would hate to do something without doctor approval, especially when it's a doctor who is up on correct protocol, but it's been so long since I felt good that I don't want to crash my E2 and ruin what I have going so far.

No offense to lowt.com but for $2400.00 a year more blood work should be included, at least the first year of treatment when your getting dialed in.

[LFH40]

The doctor called me last night to let me know he put in the prescription for anastrozole. I'm still nervous about the script for .5mg e3d. After review, seems a bit much. When I asked him, he said it's just fine. Seems like its a common dose amongst trt doctors, however, I'm thinking about doing half that dose each week.

He also recommended after a month to take my own independent estradiol test if I was concerned. Sounds like a good idea, although at the "dialing it in" stage I wish lowT provided that. It's a long 4 more months to be crashed on E2 from a higher dose. Maybe I'll do .25mg twice a week?

[Machdiesel]

No offense to lowt.com but for $2400.00 a year more blood work should be included, at least the first year of treatment when your getting dialed in.

I was also under the impression that the whole point of using them is becuase they are knowledgable and will dial you in. Then people post the same questions/concerns as other doctors and they can't even retest you to see if your dialed in.

[LFH40]

I was also under the impression that the whole point of using them is becuase they are knowledgable and will dial you in. Then people post the same questions/concerns as other doctors and they can't even retest you to see if your dialed in.

So far, that's the only down side with them that I see. I am very satisfied with their customer service, ease of appointments, quality of the meds, and that they got me into an acceptable range so quickly.

My wish is that they would cover all the testing done to get dialed in so you don't have to crash your estrogen and wait several months before getting tested again.

However, that being said, I would never go back to my regular doc, endo, nor urologist. They just don't get it at all. The site sponsor doc is easy going, just puzzled why I would start off with so much adex when I'm only on 100 mg test per week.

[ppwc1985]

I'm with lowt and your dr can ask for more bt if he thinks it is needed to get you dialed in. Mine did.

[LFH40]

I'm with lowt and your dr can ask for more bt if he thinks it is needed to get you dialed in. Mine did.

Ok, my Anastrozole will be arriving tomorrow and I'm thinking about only .25mg e3d(day after each shot). Do I double check who the doc and express my concerns or just take the .5mg twice a week and let it crash? Ugh.

[LFH40]

The lovely US postal system lost my Anastrozole script and I'm waiting to get it shipped to me. I'm wondering if my high E2 is causing me to be lethargic and feeling a lot like I did pre-trt the last few days? I took my 50mg injection of test this afternoon. Still feeling run down and foggy. Even with free t at top end of normal range, would the e2 still be the culprit?
Test 870 (348-1197)
Free test 21.3 (6.8-21.5)
estradiol 65.8 (7.6-42.6)

[LFH40]

The lovely US postal system lost my Anastrozole script and I'm waiting to get it shipped to me. I'm wondering if my high E2 is causing me to be lethargic and feeling a lot like I did pre-trt the last few days? I took my 50mg injection of test this afternoon. Still feeling run down and foggy. Even with free t at top end of normal range, would the e2 still be the culprit?
Test 870 (348-1197)
Free test 21.3 (6.8-21.5)
estradiol 65.8 (7.6-42.6)

Sorry if I have lots of questions, it's a pretty life changing event going on all these drugs for life as you know if you're doing it. Just looking for some guidance

[Metalject]

The lovely US postal system lost my Anastrozole script and I'm waiting to get it shipped to me. I'm wondering if my high E2 is causing me to be lethargic and feeling a lot like I did pre-trt the last few days? I took my 50mg injection of test this afternoon. Still feeling run down and foggy. Even with free t at top end of normal range, would the e2 still be the culprit?
Test 870 (348-1197)
Free test 21.3 (6.8-21.5)
estradiol 65.8 (7.6-42.6)

Your estradiol isn't at a terrible place. Yes, needs to come down but it's not horrific or anything like that. Anyway, if you're feeling tired and then inject testosterone , you're not all of the sudden going to feel reenergized or anything like that. It doesn't work that way, it's not like taking a pain pill. Maybe you didn't mean it that way but that's how I read it.

Anyway, I understand your frustration, just be patient. When I started TRT (actual TRT) after a decade plus of bodybuilding and having my hormones go through a run through hell, the first 3 months or so were a bit frustrating. I felt a lot of ups and downs those first months, but about 12wks into it or so things started to get better. From there my doses would vary dramatically over the course of the next few years until I finally reached a more comfortable spot. Don't misunderstand, once I got over the initial hump, those first few months, it was solid continuous improvement from there.

[LFH40]

Metalject, thank you. That was a post that really gave me promise! Thank you. Feeling really frustrated today. A few highs followed by a great big low the last few days. I know the injection isn't like a pain pill, however, I assumed that since I was at a nice 870 that by injecting I would be keeping it at that good optimal level, but I didn't feel much better 12 hours later even. But- as the day progressed, I've developed the nasty cold that my 2 year old has had the last week. That could probably play a big factor in my fatigue, mood, well being the last couple days. Provably was on the verge and my body was fighting it.

Yes. Still gotta get the E2 down a bit either way. Thank you for your take on things!

[donopat]

I have seen blood results with e2 levels in the 3-400's.. its very common... the highest I ever saw e2 was 1021 or something... dude posted his blood rsults on gh15, I couldn't believe it.. he said he felt fine , was hardly even bloated... he was doing like 1000mgs test a week.. his test levels were 5000 or 7000 but his e2 was 1021 or something like that.. it was just over 1000..

highest mine were was 138.. 6 weeks later was 78 using stane 12.5mgs eod.. that was a year ago and I haven't gotten tested since but they are definitely lower because i have been on stane 3x a week all year..

1/2 pill adex 2x a week is the proper dose..that is .5mg twice a week