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  1. #1
    jakesonyou is offline New Member
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    If Estradiol is very low before TRT, would you need an Anti-Estrogen on TRT?

    I am currently, in the process of educating myself on TRT as much as possible (I wish my doc would do the same, heaven forbid) and I was just curious about this. My Estradiol level was 6.9pg/ml on my last blood test with a reference range of 7.6-42.6. With my level being so low, would I need to take something like arimidex with a conservative trt dosing protocol (Ex: 100mg Test 2x a week, 200IU HCG 2x a week).
    Or would you suggest start without it an see what becomes of the level?

  2. #2
    FRDave's Avatar
    FRDave is offline Senior Member
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    No way of knowing how much your body will convert once on TRT, regardless of dose. I was fairly low prior and on TRT with only 100mg weekly and no AI, I'm in the mid 70 range.

    Regardless, always start your TRT with no AI and dose appropriately if needed after your follow up labs.

  3. #3
    kelkel's Avatar
    kelkel is offline HRT Specialist ~ AR-Platinum Elite-Hall of Famer ~ No Source Checks
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    There is no need to start with an AI when already low. And 200mg per week is not at all conservative. It's high end. ALWAYS start low (think 100mg) and titrate accordingly after your 6 week BW. Much easier on your body this way.
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  4. #4
    2Sox's Avatar
    2Sox is offline Knowledgeable Member
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    Quote Originally Posted by jakesonyou View Post
    I am currently, in the process of educating myself on TRT as much as possible (I wish my doc would do the same, heaven forbid) and I was just curious about this. My Estradiol level was 6.9pg/ml on my last blood test with a reference range of 7.6-42.6. With my level being so low, would I need to take something like arimidex with a conservative trt dosing protocol (Ex: 100mg Test 2x a week, 200IU HCG 2x a week).
    Or would you suggest start without it an see what becomes of the level?
    Dave gave you good advice and so did Kel. One thing I'd add is to consider starting your T dosing much lower - at 100mg/week - split into 50mg every 3.5 days. You can always increase later if necessary. The most common hCG dosing is 250iu twice a week, but if 400iu/week works for you, go for it.

  5. #5
    jakesonyou is offline New Member
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    Quote Originally Posted by kelkel View Post
    There is no need to start with an AI when already low. And 200mg per week is not at all conservative. It's high end. ALWAYS start low (think 100mg) and titrate accordingly after your 6 week BW. Much easier on your body this way.
    Sorry I mistyped that. I have a hard time with differentiating total weekly dose versus individual doses throughout the week. I did actually mean 100mg week.

    Quote Originally Posted by 2Sox View Post
    The most common hCG dosing is 250iu twice a week, but if 400iu/week works for you, go for it.
    Would you suggest starting immediately at 250iu 2x a week versus 200iu 2x a week?

  6. #6
    kelkel's Avatar
    kelkel is offline HRT Specialist ~ AR-Platinum Elite-Hall of Famer ~ No Source Checks
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    Quote Originally Posted by jakesonyou View Post
    Sorry I mistyped that. I have a hard time with differentiating total weekly dose versus individual doses throughout the week. I did actually mean 100mg week.

    Would you suggest starting immediately at 250iu 2x a week versus 200iu 2x a week?
    Measure properly when the time comes. And like 2Sox said, splitting that to 50mg every 3-4 days is even better.


    Splitting hairs with the HCG amount. Either is fine.
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