Statins and Testosterone

[kelkel]

Interesting read:

The effect of statins on testosterone in men and women, a systemati... - PubMed - NCBI

Then follow the link at the bottom to another short article.

[lovbyts]

Sounds like it goes hand in hand with the reports of statins causing muscle wasting.

It makes sense that it would lower natural testosterone but how would it affect someone on TRT?

http://www.peaktestosterone.com/Statins.aspxa recent study found that 25 out of 44 of statin users with myopathy (persistent muscle pain) has actual damage to their muscle fibers of 2% or more. The damage remained at least for a time even after the statins were discontinued. Scientists are still unsure what causes this damage but it may be that statins whack CoQ10 levels, an essential molecule and key antioxidant.


Furthermore, one recent large study of almost 3,500 men with an average age of 51 found that men on statins were twice as likely to have low testosterone. [1] The lead researcher speculated that this may be due to a decrease in pituitary output. This is probably yet another reason that statins do not improve overall mortality rates. NOTE: Some statins supposedly do not lower testosterone as badly, so you may want to talk to your doctor about that.


Just as bad is that statins have been found to be associated with erectile dysfunction in some studies. [3][4] Zocor is likely one of the worst offenders. [7] One study even comments that the erectile dysfunction reported seems to exceed the simple explanation of lower testosterone levels . [5] Lowered libido is another commonly reported side effect.

[APIs]

I've been on Crestor for >4 years @ only 5 mgs on M-W-F and it keeps my lipids perfect. Can't say it's had any affect on my total & free test levels while on TRT.

My Doc feels people run into problems when statins are dosed too high...

[kelkel]

If you guys ever want to read solid info on cholesterol pick up "The Great Cholesterol Myth" by Dr. Stephen Sinatra. Or google or youtube him. Ton's of his stuff out there.

[lovbyts]

If you guys ever want to read solid info on cholesterol pick up "The Great Cholesterol Myth" by Dr. Stephen Sinatra. Or google or youtube him. Ton's of his stuff out there.

Yeah I have read bits and pieces of it and thought the same thing before his study came out. I think it's the same with many medications.