8 months on trt and Dr consult

**Simon1972** · 08-28-2015, 04:28 PM

Hi guys reporting in on my 8 month journey to date.

I've been on creams for 5 months, injections for the rest and just had bloods drawn.

Results are causing concern, especially in the PSA results and estrogen. Below is a summary.

Test 30 (9.9-27.8) n/mol
Oestradiol 161 (<160) p/mol
SHBG 30(17-56)
Cfreetest 737( 170-670)
PSA 1.79 (0.25-2.2) 40-44 year median 0.8 ug/L

Needless to say the im happy with test and freetest.

Need guidance with the oestradiol and PSA , are they linked?

I'm meeting with Dr in two weeks to discuss and would like to push him into tamoxifen or alternative if you think it helps, I'm open to suggestions and will be using your advice during my consult.

I have been noticing slight nipple puff and feeling of emotion , not sadness, happy sad? When talking to my 4 year old.

Finally, thanks to all the advice I've been given to date. If it wasn't for this website I would be living a less than ordinary existence.

**kelkel** · 08-28-2015, 04:45 PM

Hi Simon, been a while. Question, any sexual activity (ejaculation) a day or two before your BW?
Yes, estrogen can impact your psa via the androgen receptors in the prostrate.
What does your psa normally come in at?
Tamoxifen as an alternative for what, an AI? If so, no would be the answer here.

And remember, testing estradiol (not a sensitive assay) can read much higher than the proper test and cause dosing problems when it comes to AI's.

ps: don't forget low dose cialis for BPH.

**Simon1972** · 08-28-2015, 05:01 PM

Hey kel, yeah I've been flying under the radar lately , glad you noticed my absence!

Yes to be honest , I'm a daily ejaculator, what effect would that have?

My last PSA was 1.44 now 1.79

You don't think I should be lowering my E? Even the BW has noted that result in red and marked it as high. If it has an effect on PSA I was going to mention to the doc about some form of intervention, just not sure what?

Good to see you are still here kel.

**kelkel** · 08-28-2015, 07:15 PM

Originally Posted by Simon1972

Hey kel, yeah I've been flying under the radar lately , glad you noticed my absence!

Yes to be honest , I'm a daily ejaculator, what effect would that have?

My last PSA was 1.44 now 1.79

You don't think I should be lowering my E? Even the BW has noted that result in red and marked it as high. If it has an effect on PSA I was going to mention to the doc about some form of intervention, just not sure what?

Good to see you are still here kel.

Yes, ejaculation can spike your psa for a day or two. Read this:

Ejaculation increases the serum prostate-specific antigen concentration. - PubMed - NCBI

Regarding your estrogen I'd try and obtain a sensitive estrogen assay asap and then decide on AI dosing. If you can't do that then dose your AI as minimal as possible until you can. Sometimes the difference between the two test can be striking.

What exactly is your protocol?

**Simon1972** · 08-28-2015, 09:13 PM

Originally Posted by kelkel

Yes, ejaculation can spike your psa for a day or two. Read this:

Ejaculation increases the serum prostate-specific antigen concentration. - PubMed - NCBI

Regarding your estrogen I'd try and obtain a sensitive estrogen assay asap and then decide on AI dosing. If you can't do that then dose your AI as minimal as possible until you can. Sometimes the difference between the two test can be striking.

What exactly is your protocol?

Hi kel, Currently I'm dosing 0.3 mg test E, every 3.5 days Tues night\ sat morning.

**kelkel** · 08-29-2015, 06:51 AM

If you end up using adex take it the day of or day after injection for maximum effect.

**Simon1972** · 08-30-2015, 05:53 AM

Originally Posted by kelkel

If you end up using adex take it the day of or day after injection for maximum effect.

Right on Kel, ill be sure to push for that- id hate to run high E at this level for too much longer considering prostate issues run in the family- will ask for a sensitive essay for E.

man , thanks for all you do for this forum, your legacy will live on, hope you realise that.

**AR's King Silabolin** · 08-30-2015, 06:10 AM

0,3 mg test e?

**Simon1972** · 08-30-2015, 07:28 PM

Originally Posted by Silabolin

0,3 mg test e?

Correction. 0.3ml shot @250mg\ml.
Equates to 75mg x2 a week , total 150mg a week

**kelkel** · 08-30-2015, 09:16 PM

Originally Posted by Simon1972

Right on Kel, ill be sure to push for that- id hate to run high E at this level for too much longer considering prostate issues run in the family- will ask for a sensitive essay for E.

man , thanks for all you do for this forum, your legacy will live on, hope you realise that.

No worries and thanks. We all learn from each other here and have some fun along the way.
Post up how you do or pm me.

**DanMan250** · 08-31-2015, 09:10 PM

Hey Simon, check your PM re your doc and reply please.
Thanks.

**Simon1972** · 09-22-2015, 11:24 PM

Just go back from the Dr, gave me a script for anastrozole 1 tab a week, and asked me to maintain 150 mg test e per week. I've halved my trigs to 0.8 from 1.5 so I'm happy with that. Hopefully the anastrozole will help with my PSA levels although Dr isn't fazed by it. Sitting at 1.79 ( 0.25- 2.2)

**kelkel** · 09-23-2015, 07:58 AM

Is this based on your initial BW in post #1? If so, it would have been good to pull a sensitive E2 assay like mentioned previously. There can be a big difference between the two test results. Also, I would not recommend 1 mg either at once or broken up. I'd suggest quartering it and taking it (.25) the day you inject and 3-4 days later.

Also, consider low dose cialis at 5-10 mgs per day. It's approved here in the states for BPH. It's simply a very healthy drug for men to take.

A review of the use of tadalafil in the treatment of benign prostatic hyperplasia in men with and without erectile dysfunction. - PubMed - NCBI

**Roger11** · 09-23-2015, 09:06 AM

Lovebytes linked me a while ago, yes High e2 can have prostate negative effects, i back kelkel up on that. The study is around in one of my threads somewhere....

**Simon1972** · 09-24-2015, 02:21 AM

Originally Posted by kelkel

Is this based on your initial BW in post #1? If so, it would have been good to pull a sensitive E2 assay like mentioned previously. There can be a big difference between the two test results. Also, I would not recommend 1 mg either at once or broken up. I'd suggest quartering it and taking it (.25) the day you inject and 3-4 days later.

Also, consider low dose cialis at 5-10 mgs per day. It's approved here in the states for BPH. It's simply a very healthy drug for men to take.

A review of the use of tadalafil in the treatment of benign prostatic hyperplasia in men with and without erectile dysfunction. - PubMed - NCBI

yes it is off the first bloodwork, thats the latest i have- he has had me using the same test since i started so i suspect he wanted to keep the tests the same so we could track it using the same reference scales- i have requested a sensitive essay, but he dismissed it as not nesssary for the above mentioned reasons. All things being equal- i didnt want go get into a argument with him as im happy he has me pointed in the right direction after looking for so many years and for the most part seems knowledgable. i was at 12.8 T now at 30T, i will take your advice and split dose at 0.25mg 2 x a week , i have another test due in a couple of months. and the addition of arimidex will be the only change to protocol.

what would you expect at that dose for my E to get down to considering im at 161 ( <160)

**kelkel** · 09-24-2015, 08:54 AM

Well, it's still a shame he won't upgrade to a more specific (read-accurate) test. Consistency is great but he's being consistent with a test that is not consistent for us. No clue where it will bring you as we all react differently to it but his original dosage of 1 mg could possible crash your E2. Consider guys on a 500 mg cycle normally use .25 mg EOD. If possible retest your E in a month.

**DanMan250** · 09-24-2015, 12:57 PM

Kelkel is right about splitting your arimidex dose. Don't go higher than 0.25mg 2 x week, then retest with a sensitive estradiol test in about a month. Then you can adjust your dose if need be. If your estradiol goes too low, like it will on 1mg once a week, you will have all sorts of problems. You might think your doc sounds knowledgeable, because you're not well read on TRT yet. Honestly, your doc sound f#cking clueless suggesting 1mg of adex once a week and refusing to run a sensitive estradiol test. You will gain much more knowledge than your doc by reading all the posts on this forum and other good TRT forums, like Nelson Vergel's forum and Crisler's forum.

**Simon1972** · 09-25-2015, 02:08 AM

Will definitely push it home harder at next visit, in fact I might ask him to write out another blood work order with both tests for comparison sake. So I can get the sensitive version sooner rather than later, thanks for the feedback guys, invaluable as always