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  1. #1
    ruffcute is offline Associate Member
    Join Date
    Sep 2006
    Posts
    318

    On basic TRT now have low Cortisol

    I have been on basic TRT for a number of years now. When I say basic, I mean purely for functional normal level replacement therapy. I take just enough to keep my Free test in the 400-500 mid range.

    The last couple of years have been pretty hard, and life has sucked somewhat, divorce, seeing the kids less etc so I know my stress hormones would be a little weird.
    But over the last couple of years I have seen my TRT and other general hormones stay normal, but my Cortisol really fluctuate and now staying pretty low.

    Here are some of my labs for Cortisol.
    Aug 2020 - 490 nmol/L 170-500 range
    Feb 2021 - 186 nmol
    Oct 2021 - 114 nmol
    Dec 2021 - 115 nmol
    Jan 2022 - 172 nmol

    If you need any other labs, I can happily look them up. I’m just not sure what to write down right now.

    Does anyone know why I might be experiencing such low cortisol? Or if there would be a TRT factor?

    I think the next step from the doctors perspective might be a ACTH stimulation test.
    Unless they decide that 172 nmol is now in the range therefore screw further testing - I had that originally with my TRT.

    Current meds I’m on:
    Test Cyp - 0.3ml x 2 times a week 200mg/ml
    HcG - 300 ui x 2 times a week
    Anastrozole - 0.5mg x 2 times a week
    Last edited by ruffcute; 02-06-2022 at 06:40 AM.

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