Thread: hgh and ghrh
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01-30-2005, 03:56 PM #1
hgh and ghrh
Can anyone tell me what the difference is ??? hgh we all know.. and ghrh = growth hormone releasing hormone....???
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01-30-2005, 04:06 PM #2
Was it rHGH maybe, that is the name for synthetic HGH, which is what you want.
I think a research company advertises something called gHGH...
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01-30-2005, 04:09 PM #3
ghGH, glycosylated hGH
Never heard of anyone selling this, had to look into some research papers to find it.
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01-30-2005, 04:10 PM #4
Glycosylated human growth hormone variant
J Ray, BK Jones, SA Liebhaber and NE Cooke
Department of Human Genetics, University of Pennsylvania, Philadelphia 19103.
The human growth hormone variant (hGH-V) gene is expressed by the syncytiotrophoblastic layer of the human placenta in two forms: hGH-V mRNA encoding a 22 kD protein, and hGH-V2 mRNA which retains intron 4 and is expected to encode a 26 kD protein. There is a predicted N- linked glycosylation site in hGH-V at amino acid 140 that is absent in both hGH-V2 and in the highly homologous normal pituitary GH (hGH-N). Cell lines transfected with the hGH-N gene secrete 22 kD GH and the 20 kD product of an alternatively spliced mRNA, while cell lines transfected with the hGH-V gene secrete three proteins of 22, 24, and 26 kD. To determine whether any of these hGH-V isoforms are glycosylated, the cell lines were grown in the absence and presence of tunicamycin. In addition, conditioned medium from metabolically labelled hGH-V transfected cells was separately digested with peptide:N- glycosidase F and endoglycosidase H. The 26 and 24 kD bands were both absent from the media after tunicamycin treatment and were both sensitive to peptide:N-glycosidase F treatment. Endoglycosidase H digestion resulted in the selective loss of the 24 kD band. These results indicate that hGH-V is partially modified posttranslationally by N-linked glycosylation in a fibroblastic cell line.
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01-30-2005, 04:15 PM #5
no this definately stands for human growth release hormone
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01-30-2005, 04:18 PM #6
PM me...
There is hgh releasing hormone...
I have never seen a synthetic on the market yet. Many bad tries exist though.
Originally Posted by Kevan
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01-30-2005, 04:24 PM #7
Ooops I originally read ghGH not GhRH...
GhRH is the correct abbreviation for growth hormone releasing hormone, but I would be skeptical if anyone claims to be selling it.
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01-30-2005, 04:31 PM #8
ok thanks.. but what is the difference between the 2 of them?
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01-30-2005, 04:54 PM #9
ghRH sttimulates the production of HGH...
It is your bodies hormone to signal it to produce HGH
Originally Posted by Kevan
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01-30-2005, 07:54 PM #10
sure it's not GHRP or rHGH? Never heard of growth hormone releasing growth. GHRP is Growth Hormone Releasing Peptide.
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01-30-2005, 07:58 PM #11
ghRH is a pituary hormone...
I have never heard of it being synthesized though...
Originally Posted by LuvMyRoids
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01-31-2005, 10:32 AM #12Member
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I have seen GHRH available from some pharmaceutical companies.
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02-01-2005, 05:39 PM #13Anabolic Member
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Sounds like you're talking about GHRP-6 - a peptide that acts on ghrelin, which releases GH. This compound is available at three asterisks.
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02-01-2005, 05:51 PM #14
no... i've seen "three asteriks" talk about working on GhRH..... i think their going to be selling it soon....
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02-01-2005, 06:09 PM #15Anabolic Member
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Are you talking about GHRP? My understanding is it has been available for some time. I don't know what GhRH is. The one in the pipeline that I know of is the Oratropin - Oral LR3 IGF-1.
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