At what point with respect to dosage and length of cycle of Lr3 IGF-1 would you say that most will experience visible and irreversible organ/intestinal growth?

Am I incorrect in the assumption that is it common for professional bodybuilders to use Lr3 IGF-1 for months on end at very high dosage simultaneously with GH and Humalog with few or no breaks?

Is this the main factor in the increase of distended abdomens and/or lbm we see in the sport today?

Thanks