hgh and igf

[ryduck1990]

We all know that some generic gh labs pass their gh as actual igf. But what is the difference in what gh does over igf? gh converts to igf anyways, so why go through the extra step?

[Sgt. Hartman]

Most people say that supplementing with IGF-1 LR3 is lacking in results.

GH causing the liver to produce IGF-1 and IGF-2 are the main benefits of GH and do cause most of the growth as a result, but there are other benefits. Fat/Muscle/Organ cells all have GH receptors. GH directly regulates muscle and fat metabolism, which impacts on body composition and insulin sensitivty. For example, fat cells have growth hormone receptors, and growth hormone stimulates them to break down triglycerides to use as fuel and supresses their ability to take up and accumulate circulating lipids, ie more difficult to store new body fat. GH has also been shown to have direct healing properties on damaged organs (skin, liver, etc.), as well as greatly enhance the immune system function.

[Isma]

From "Putting it all together" by RedBaron.

DESCRIPTION OF THE ELEMENTS OF THIS CYCLE

HGH
HGH should ideally be used for 20-30 week cycles (or longer). The dosage should be between 2-3IU per day if you are using GH primarily for fat loss, 4-5 IU’s a day for both fat loss and muscle growth, and approximately 1.0 – 2.0 IU’s a day for females. It is best to split your injections 1/2 first thing in the morning, 1/2 early afternoon if your dose is above 3.0 IU’s per day. Your pituitary will naturally produce about 6-9 pulses of GH per day. Each injection you take will create a negative feedback loop that will suppress these pulses for about 4 hours. By taking your injections first thing in the morning and early afternoon you will still allow your body to release its biggest pulse, which normally occurs shortly after going to sleep at night.

When starting out with your HGH cycle, for most people it is wise to begin you dose at 1.5 – 2.0IU per day for the first couple of weeks, and then begin increasing your dose by 0.5 unit every week or two until you reach your desired level. While it isn't an absolute neccessity to do this, if you are sensitive to the type of sides HGH present you will often times avoid these sides of joint pain/swelling, and bloating/water retention by slowly acclaimating to your ultimate 4-5 IU/day goal.

You should use an U100 insulin syringe for injecting HGH, and inject it subQ into your a**omen, obliques, top of thighs, triceps. Rotate injection sites. HGH can have a small localized fat loss benefit, so keep this in mind when choosing your injection sites.

IGF-1
When HGH makes it pass through the liver, a release of IGF-1 is a result. IGF-1 appears to be the key player in muscle growth. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues. While HGH will cause an increase in your IGF-1 level over the course of a few months, HGH has a cumulative effect, so the addition of IGF-1 will greatly speed up the time to results.

There are two types of IGF-1 that will typically be used by bodybuilders. One is bio-identical huIGF-1, a 70 amino acid string. The other is Long R3 IGF-1, which is an 83 amino acid analog of human IGF-I comprising the complete human IGF-I sequence with the substitution of an Arg for the Glu at position 3 (hence R3), and a 13 amino acid extension peptide at the N-terminus (hence the long). This 13 amino acid "side chain" helps prevent the IGF-1 from being so easily bound, and thus increases its active window exponentially. Which of these you use depends on your goal.

HuIGF-1 is very short lived in the body (half life of probably around 10 minutes). This type of IGF-1 is very useful if you are seeking local site growth. Since it is so short lived, little of the IGF-1 makes it to other tissues and IGF-1 receptors in the body. The way to inject this is immediately post work out into the muscle that you wish to have local site growth. Use a U100 insulin syringe, and inject 60-80mcg’s bilaterally into the desired muscle immediately post workout. For this type of IGF-1, I would use it workout days only or if desired you could inject on non-workout days first thing in the morning into a muscle group worked the previous day.

For Long R3 IGF-1, it isn’t as critical that you inject into a local site as long R3 has a active window of many hours, and is designed specifically to resist being bound by IGF binding proteins.

Since it is common to reconstitute this type of IGF-1 with Benzyl Alcohol, Acetic Acid, or Hydrochloric Acid, I would still recommend that you inject intra-muscular. While for some purposes of nerve regrowth, etc. subQ is a somewhat superior injection method, it can and probably will leave a nice red irritated spot if you inject subQ, and it is not superior for muscle growth purposes anyway.

I still inject into a muscle just worked to take advantage of increased IGF-1 receptors present as a result of tearing down muscles with workout, but because of the long activity window of this type of IGF-1 any muscle will work well and give you good results,. I would suggest that you inject between 40-80mcg’s per day everyday immediately post workout on workout days, and first thing in the morning on non-workout days.

Use a U-100 insulin syringe with 1/2" needle to inject IGF-1 intramuscular (bilaterally for HuIGF-1, bilaterally optional for Long R3)

[ScotchGuard02]

Real IGF-1 is pretty expensive to get, if you can get it.

[Isma]

Real IGF-1 is pretty expensive to get, if you can get it.

If I'm not wrong, it's not the best for BodyBuilding targets. It's only a few minutes in the body.

[ScotchGuard02]

Yeah, it doesn't last too long in the body. It's longer then a few minutes. Maybe a couple of hours. It doesn't disappear 100% but concentration drops off pretty rapidly.