Peptides Studies (Collection of)

[Muscletech]

Hi guys! I'm linking here a series of studies/researches on the peptides (GHRH, GHRP, CJC1295-DAC, IGF-1 and more...) From buypeptides.org

I hope to help you!
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IGF1 Studies:

This IGF-1 Study on males subjects injected daily for 6 weeks (with either HGH alone, IGF-1 alone or IGF-1 + HGH together) indicated increased lean body mass, increased strength and decreased fat mass in all groups. An interesting point to note though was that the increases only persisted for the whole 3 months in those injecting IGF-1 + HGH, giving validity to the point that IGF-1 loses its effectiveness after a certain period of time and therefore should be used 1 month on and 1 month off to re-sensitize the muscle receptors.

http://www.annals.org/content/125/11/865.short



PEG MGF (Mechano growth factor) studies:

This 2005 MGF Scientific Report discusses the potential of the peptide to enhance physical training and also potentially be misused as a doping agent in sports due to its difficult detection. The article mentions the finding in a previous study that a single intramuscular injection of MGF into the muscle of a mouse caused a 25% increase in muscle size within just 3 weeks.

http://www.ncbi.nlm.nih.gov/pmc/arti...v039p00787.pdf



HGH Fragment 176-191 Studies:


This 2004 HGH Fragment 176-191 Study (also known as AOD9604) indicates that the peptide was highly successful at stimulating the metabolism of body fat in humans and is the first drug to ever do so - all other weight loss drugs (such as Sibutramine) contribute to loss of body weight indirectly by reducing appetite and not actually burning fat itself.
The study was conducted over 3 months at 6 different doses with one of the most interesting conclusions being that the lowest daily dose of 1mg (1000mcg) was found to be the most effective. Since the 1mg dose was taken orally, it would be the equivalent of approximately 250mcg (0.25mg) by injection. The average overall weight loss in 3 months was 3kg of fat, 300% more than for those test subjects not taking the peptide.
Additionally, unlike normal HGH injections which have negative effects on blood glucose, HGH Fragment 176-191 did not negatively effect glucose tolerance, but rather improved it and also improved cholesterol levels.

http://www.news-medical.net/news/2004/12/16/6878.aspx



CJC1295 (Mod. GRF-1-29) or GHRH Studies:

This 2005 Modified GRF 1-29 Study (referred to as GHRH 1-44) on women who injected the peptide for 90 days (3 months) indicated several key benefits of the peptide such as: an increase in Growth Hormone (GH) and IGF-1 levels; reduction in fat mass (stomach fat) and an increase in athletic physical performance (such as walking and stair climbing) - all of which occurred 100% as a result of simply taking the peptide (they did not do any special physical training or dieting in conjunction with the injections).
A 2004 Study, in men, indicated similar findings after 3 months of Modified GRF 1-29 injections: a 200% increase (doubling) of both GH and IGF-1 levels; an increase in fat free mass (muscle) as well as a reduction in abdominal fat; and an improvement of physical performance, measured by the time it took to walk 30 minutes and to ascend four flights of stairs. Once again these excellent results were achieved by the injections alone, no special diet and weight or cardio training were followed. So you can well imagine the sort of results which could be achieved with the addition of careful dieting and training.

Both studies serve to indicate 5 things:

1. CJC-1295 (Modified GRF 1-29) is anti-aging as it's a potent increaser of GH and IGF-1 levels which decline with age
2. Results don't happen overnight and you should take the product for 3 months minimum
3. The peptides are effective on their own (however results would be far superior with diet and exercise)
4. CJC-1295 Peptides are safe and have been used for many years in scientific circles
5. The peptides improve athletic performance, fat loss (particularly stomach fat) and increase muscle mass

The two studies:

2005: http://www.ncbi.nlm.nih.gov/pubmed/16260425
2004: http://j***.endojournals.org/content/89/12/6325.full


CJC1295 DAC Studies:

The following 2006 CJC-1295 DAC Study shows that the peptide is a potent and long-lasting stimulator of GH and IGF-1 levels. After just one injection of the product, GH levels increased by 200-1000% for 6 days and remained higher than normal for up to 1 month in healthy subjects aged 21-61 years.
While no studies have been undertaken to test for the fat-loss, muscle building and performance enhancing effects of CJC-1295 DAC it would be safe to assume that since it is a potent and long-lasting increaser of Growth Hormone and IGF-1 levels, all of the associated benefits indicated in the CJC-1295 (Modified GRF 1-29) studies would be realised with long term use with the added benefit of fewer injections. Additionally, with the long half-life, there is no concern regarding any potential food interactions which might cause the peptide to be less effective.
CJC-1295 DAC, with its long half-life (i.e. 1-2 weekly injections) is therefore a much more convenient alternative to GRF 1-29 and/or GHRP peptides. Furthermore, feedback from experienced users indicates it is much more effective at achieving the desired results on body composition. Since however no long-term studies have been conducted using CJC-1295 DAC, we recommend never using it for more than 6 months at a time to give your pituitary gland a break from the continual pulses of GH.

http://j***.endojournals.org/content/91/3/799.full



GHRP-6/GHRP-2 Studies:

This GHRP-6 Study makes a number of interesting conclusions about the efficiency of GHRP-6 at releasing Growth Hormone including that it is much more effective than Modified GRF 1-29 at releasing GH (although a combination of both GHRP and Modified GRF 1-29 is much more effective than either product alone). It indicates that a dosage of as little as 10mcg can induce a significant GH pulse, however a dosage of 100mcg is much more effective than 10mcg.
The following GHRP Study (the second) shows that Ipamorelin has similar effectiveness to GHRP-6 at promoting GH release at dosages of 100mcg, however unlike GHRP-6 and GHRP-2 it does so without increasing the detrimental hormones cortisol, aldosterone or prolactin which can be responsible for such negative side effects as stress, water retention and decreased sex drive.
The study also indicates that at a comparable dosage, GHRP-2 is approximately 30% more efficient at creating a GH pulse than GHRP-6 making it the strongest and most cost effective GHRP peptide.

First studie: http://www.professionalmuscle.com/fo...es-figure5.jpg
Second studie: http://www.ncbi.nlm.nih.gov/pubmed/9849822

[Optima25]

Thanks bro. Very helpfull

[Muscletech]

You are welcome