Quote Originally Posted by Atomini View Post
Nolva has a higher affinity for the receptors than estrogen itself, that's why it works so well otherwise it would not be used.

The key piece of knowlege here is that Nolvadex was not developed to stop gyno in steroid -using athletes. It was developed as a breast cancer fighting drug, as most breast cancers are exacerbated by estrogen binding to receptor sites on breast tissue, causing growth. If cancerous cells exist there, you can see how this would be a problem. The idea is that after breast cancer surgery, the female takes nolvadex because it has an EXTREMELY higher affinity for the receptors on breast tissue than estrogen does, thereby reducing the chance of cancer recurring by a great deal.

The other side to this coin, however, is that nolvadex really IS an estrogen, albeit a 'fake' estrogen in breast tissue (a placeholder, if you will, that masquerades as the real estrogen but does absolutely nothing when it gets there). The thing with that is, though nolvadex may act as an estrogen antagonist in breast tissue, it acts as an estrogen in other tissues in the body.
What types of issues can I run into from that?