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08-21-2013, 06:37 AM #1
PCT with Torem and liquid Tamox
Has anyone run these together for a PCT and what was your result? After my last cycle I ran nolva and clomid and the sides were insane for me to say the least. I am curious to find out how others here did with this and if I can expect any different sides then with the clomid. ED? Insomnia? Thanks
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08-21-2013, 06:54 AM #2
and what should my does be running these together?
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08-21-2013, 06:58 AM #3
tamox 40/20/20/20/20
torem 120/60/60/60/60
going with this for my next PCT
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08-21-2013, 11:31 AM #4Originally Posted by mr.slippyfist69
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08-21-2013, 12:29 PM #5Associate Member
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Originally Posted by mr.slippyfist69
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08-21-2013, 12:54 PM #6Originally Posted by Negative Knight
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08-21-2013, 03:22 PM #7
I had vision issues and was def very moody----100 mg
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08-21-2013, 03:46 PM #8
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08-21-2013, 04:14 PM #9Associate Member
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Originally Posted by jim230027
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08-21-2013, 04:59 PM #10Originally Posted by Negative Knight
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08-21-2013, 06:07 PM #11
I've run tore/tamox for pct several times and recovered fine.
Tore 120/120/60/60.......
Tamox 40/20/20/20......
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08-21-2013, 07:15 PM #12Associate Member
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Originally Posted by jim230027
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08-21-2013, 09:34 PM #13
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Tamoxifen , ocular toxicity, & oxidative stress
A heads up re: serms and vesion sides. The article linked to below proposes that the ocular damage caused by tamoxifen is due to oxidative stress. The authors suggest that the use of antioxidants (ie: IMO especially NAC because its a glutathione precursor)may help prevent such damage.
Exp Biol Med (Maywood). 2004 Jul;229(7):607-15.
Oxidative stress plays an important role in the pathogenesis of drug-induced retinopathy.
Toler SM.
Clinical Safety and Risk Management, Pfizer Inc., Pfizer Global Research and Development, 50 Pequot Avenue, New London, CT 06320. [email protected]
Several pharmaceutical agents have been associated with rare but serious retinopathies, some resulting in blindness. Little is known of the mechanism(s) that produce these injuries. Mechanisms proposed thus far have not been embraced by the medical and scientific communities. However, preclinical and clinical data indicate that oxidative stress may contribute substantially to iatrogenic retinal disease. Retinal oxidative stress may be precipitated by the interaction of putative retinal toxins with the ocular redox system. The retina, replete with cytochromes P450 and myeloperoxidase, may serve to activate xenobiotics to oxidants, resulting in ocular injury. These activated agents may directly form retinal adducts or may diminish ocular reduced glutathione concentrations. Data are reviewed that suggest that indomethacin, tamoxifen, thioridazine, and chloroquine all produce retinopathies via a common mechanism-they produce ocular oxidative stress
Full article can be accessed here:
Oxidative Stress Plays an Important Role in the Pathogenesis of Drug-Induced Retinopathy
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08-30-2013, 01:49 AM #14
That was a good read man thanks a lot for the info
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