Quote Originally Posted by Droq13 View Post
I've gotten mixed answers thats why.. For test, some people say start with 300mg, then 400, then 500mg 3rd cycle... Looks like i'll bump it up to 500mg a week. Can I pin once since it's a long esther or do I have to pin twice?

Reason for the HCG starting 2 weeks later is I've read since Test E is a longer esther, I can wait 2 weeks. Wasn't sure on this one that's why I'm asking.

As for Clomid, I read Swale's PCT guide and it said that clomid and nolva don't have significant benefits running together. I've seen a bunch of sample PCT's use Clomid/Nolva together, and some that use only nolva.
Quote Originally Posted by austinite View Post
Still no backing, just random statements. You keep saying "I've read somewhere" yet you go into no detail....

There are 2 major components involved in recovery. Testosterone production and Spermatogenesis.

LH and FSH are both required for the equation. LH is produced by the pituitary and stimulates the Leydig cells to produce testosterone. Once testosterone is in production it works alongside FSH and stimulates sertoli cells to produce sperm. Sperm production is hindered if either of these are unhealthy. They both work in synergy. You need BOTH to be at healthy levels.

clomid has multiple effects. It's an anti-estrogen, so it obviously decreases the estrogenic effects in your body by stimulating the Hypothalamus back to life and sending gonadotropin releasing hormone (GnRH) to your pituitary, so that LH/FSH can be secreted.

Nolva boosts the effects of clomid because it put clomid into "competition" mode where they both fight for a receptors to bind to. This competitiveness will only occur with the presence of BOTH nolva/clomid, and will inevitably resolve the issue of excess estrogen in the Hypothalamus. This will trigger both LH and FSH to crank UP, as the high estrogen in this cluster is suppressive. This entire scenario is not as effective with only one drug.

Furthermore varying the compounds; Since we know both stimulate LH, what most don't know is that the act is different. clomid boosts the amplitude of LH serum, but has no effect on the frequency. Nolvadex is the complete opposite in that area, where it boosts the actual frequency of LH and has no effect on its amplitude.

You're probably assuming they're identical and overpowering... clomid is a mixed agonist/antagonist for the estradiol receptor. Nolva is also mixed, however.... it is a pure antagonist in the E receptor in breast tissue. There is a reason that clomid is not recommended for gynecomastia reversal, but Nolva is.

Can you recover with just Nolvadex, or just clomid? Well, anything is possible. But why would you take that risk if the combination gives you a much better chance? To save a few bucks and risk your health? clomid when coupled with Nolvadex is clearly the safer choice over using either compound individually.

There's NEVER a good reason to spew random information and flood the boards with random statements. You also JUST started a thread asking about running multiple compounds. Does your random rule not apply to you? Not trying to beat you up here, Zero, but let's be logical, at least.
Quote from austinite... he knows his shit