Heart damage from Testosterone use? It's possible?

[AR's King Silabolin]

I agree with slacker and bb.

I want to add, bodybuilders who die before their time, often die from heartattack. The heartattack is not from an enlarged heart. but from narrow veins/arteries in the heart. Triglycerides, high ldl, low hdl and high blood pressure are riskfactors.
Therefore i think its important to avoid high bloodpresure (sodium/potasium ratio) and to eat lots of arteriecleaning foodtypes. Also drink lots of water and dont be afraid of N0s, as they lower BP. Larginine is actually real good for bloodpressure and your cardiovascular system.
Also do cardio, specially when on as cardio can help on bad cholestrol and better all your cardiovascular system.

[Slacker78]

I agree with slacker and bb.

I want to add, bodybuilders who die before their time, often die from heartattack. The heartattack is not from an enlarged heart. but from narrow veins/arteries in the heart. Triglycerides, high ldl, low hdl and high blood pressure are riskfactors.
Therefore i think its important to avoid high bloodpresure (sodium/potasium ratio) and to eat lots of arteriecleaning foodtypes. Also drink lots of water and dont be afraid of N0s, as they lower BP. Larginine is actually real good for bloodpressure and your cardiovascular system.
Also do cardio, specially when on as cardio can help on bad cholestrol and better all your cardiovascular system.

Yes, agree. L-Arginine is linked with NO conversion but ONLY to higher dosages ( many studies proven it ) and it could be hard for a man handle them without bad sides. Anyway, i've experimented by myself that in some individuals, this could be work well ( for example me ) as with 5 gr./ED, my blood pressure lowered. I suppose its effectiveness could vary from and individual to another one.

[AR's King Silabolin]

Yes, agree. L-Arginine is linked with NO conversion but ONLY to higher dosages ( many studies proven it ) and it could be hard for a man handle them without bad sides. Anyway, i've experimented by myself that in some individuals, this could be work well ( for example me ) as with 5 gr./ED, my blood pressure lowered. I suppose its effectiveness could vary from and individual to another one.

I have an extremely trusted source (James Tiny West on youtube) who says its perfect to drop 12 g before every workout.
I have done this the last weeks and the only sides i have experienced is a little more liquid shit (sorry for the details) the day after. No bloatfeeling or stomach discomfort.
+ All the goodies ofcourse.

[Slacker78]

I have an extremely trusted source (James Tiny West on youtube) who says its perfect to drop 12 g before every workout.
I have done this the last weeks and the only sides i have experienced is a little more liquid shit (sorry for the details) the day after. No bloatfeeling or stomach discomfort.
+ All the goodies ofcourse.

That's good. If you tolerate it, god bless you. For me it's hard as i have gastritis and L-Arginine has an acid PH... so my stomac could be anger...

[Slacker78]

In every case, the most important things has to be scrupulously observed are RBC/HCT, LDL/HDL and Homocysteine. The latter is understimated but it could be a silent risk of potential heart attack. Further, androgens increase Tromboxanes A2 receptors density which is strongly related to imparied vascular reactivity. For these reasons, i suppose a baby-aspirin ( which blocks Tromboxanes synthesis ), is a MUST during an AAS cycle. As you can see, there's a lot of things to keep on eye regard cardiovascular system and it enough to neglect just one, to leave an open door for heart damages and vascular system.

[hammerheart]

In every case, the most important things has to be scrupulously observed are RBC/HCT, LDL/HDL and Homocysteine. The latter is understimated but it could be a silent risk of potential heart attack. Further, androgens increase Tromboxanes A2 receptors density which is strongly related to imparied vascular reactivity. For these reasons, i suppose a baby-aspirin ( which blocks Tromboxanes synthesis ), is a MUST during an AAS cycle. As you can see, there's a lot of things to keep on eye regard cardiovascular system and it enough to neglect just one, to leave an open door for heart damages and vascular system.

Elevated homocysteine it's not an issue on its own, rather an indicator for folate/b12 deficiency, either due to poor diet or enzymes polymorphism. These are common in the med basin.

[Slacker78]

Elevated homocysteine it's not an issue on its own, rather an indicator for folate/b12 deficiency, either due to poor diet or enzymes polymorphism. These are common in the med basin.

AAS could raise HCY levels by themselves in absence of folate/B12 deficiency. Elevated HCY level effects are well known on cardiovascular system.

[hammerheart]

AAS could raise HCY levels by themselves in absence of folate/B12 deficiency. Elevated HCY level effects are well known on cardiovascular system.

Research on HCY is still ongoing. Anyway I found this one study on chronic AAS ab(use).

Homocysteine induced cardiovascular events: a consequence of long term anabolic‐androgenic steroid (AAS) abuse

It kind of supports your statement, and is a good reason to recommend remethylation factors (methylcobalamin, folate, B6) to anyone on cycle.

Those will help manage HCY.


Also remember - blood values only tell part of the story. You can have normal B9/B12 readings but elevated HCY is often indicative of intracellular MB12 deficiency.

[Slacker78]

Research on HCY is still ongoing. Anyway I found this one study on chronic AAS ab(use).

Homocysteine induced cardiovascular events: a consequence of long term anabolic‐androgenic steroid (AAS) abuse

It kind of supports your statement, and is a good reason to recommend remethylation factors (methylcobalamin, folate, B6) to anyone on cycle.

Those will help manage HCY.


Also remember - blood values only tell part of the story. You can have normal B9/B12 readings but elevated HCY is often indicative of intracellular MB12 deficiency.

Yes, sure. An injection/week of vit B complex it's due on cycle.

OT: Are you Italian one ?

[hammerheart]

OT: Are you Italian one ?

Yeah typical southerner from the capital of Apulia.

[numbere]

Therefore i think its important to avoid high bloodpresure (sodium/potasium ratio) and to eat lots of arteriecleaning foodtypes.

Your sodium intake has little effect on blood pressure.

Cochrane did a massive review of 34 studies which examined the effect of salt restriction on reducing blood pressure.

They found that restricting sodium intake only reduced blood pressure by a few mm Hg on average.

If you read the studies done on arginine it takes 30g taken IV to produce vasodilation.

When arginine is taken orally it has a 70% absorption rate.

This means you'd have to take at least 43g orally for vasodilation to occur.

If you want to have blood flow increases similar to arginine IV infusion you'd have better results manipulating insulin.

James Vest has no idea what he's talking about.

[The Deadlifting Dog]

James Vest has no idea what he's talking about.

But he's on the intrawebs!!!!

[TestoSuper]

I agree with slacker and bb.

I want to add, bodybuilders who die before their time, often die from heartattack. The heartattack is not from an enlarged heart. but from narrow veins/arteries in the heart. Triglycerides, high ldl, low hdl and high blood pressure are riskfactors.
Therefore i think its important to avoid high bloodpresure (sodium/potasium ratio) and to eat lots of arteriecleaning foodtypes. Also drink lots of water and dont be afraid of N0s, as they lower BP. Larginine is actually real good for bloodpressure and your cardiovascular system.
Also do cardio, specially when on as cardio can help on bad cholestrol and better all your cardiovascular system.

I totally agree.
I have ever pressure under control ( 120/75 last measurement ) do a lot of cardio and lipid profile is in order and ever under control