Heart damage from Testosterone use? It's possible?

[Slacker78]

In every case, the most important things has to be scrupulously observed are RBC/HCT, LDL/HDL and Homocysteine. The latter is understimated but it could be a silent risk of potential heart attack. Further, androgens increase Tromboxanes A2 receptors density which is strongly related to imparied vascular reactivity. For these reasons, i suppose a baby-aspirin ( which blocks Tromboxanes synthesis ), is a MUST during an AAS cycle. As you can see, there's a lot of things to keep on eye regard cardiovascular system and it enough to neglect just one, to leave an open door for heart damages and vascular system.

[hammerheart]

In every case, the most important things has to be scrupulously observed are RBC/HCT, LDL/HDL and Homocysteine. The latter is understimated but it could be a silent risk of potential heart attack. Further, androgens increase Tromboxanes A2 receptors density which is strongly related to imparied vascular reactivity. For these reasons, i suppose a baby-aspirin ( which blocks Tromboxanes synthesis ), is a MUST during an AAS cycle. As you can see, there's a lot of things to keep on eye regard cardiovascular system and it enough to neglect just one, to leave an open door for heart damages and vascular system.

Elevated homocysteine it's not an issue on its own, rather an indicator for folate/b12 deficiency, either due to poor diet or enzymes polymorphism. These are common in the med basin.

[Slacker78]

Elevated homocysteine it's not an issue on its own, rather an indicator for folate/b12 deficiency, either due to poor diet or enzymes polymorphism. These are common in the med basin.

AAS could raise HCY levels by themselves in absence of folate/B12 deficiency. Elevated HCY level effects are well known on cardiovascular system.

[hammerheart]

AAS could raise HCY levels by themselves in absence of folate/B12 deficiency. Elevated HCY level effects are well known on cardiovascular system.

Research on HCY is still ongoing. Anyway I found this one study on chronic AAS ab(use).

Homocysteine induced cardiovascular events: a consequence of long term anabolic‐androgenic steroid (AAS) abuse

It kind of supports your statement, and is a good reason to recommend remethylation factors (methylcobalamin, folate, B6) to anyone on cycle.

Those will help manage HCY.


Also remember - blood values only tell part of the story. You can have normal B9/B12 readings but elevated HCY is often indicative of intracellular MB12 deficiency.

[Slacker78]

Research on HCY is still ongoing. Anyway I found this one study on chronic AAS ab(use).

Homocysteine induced cardiovascular events: a consequence of long term anabolic‐androgenic steroid (AAS) abuse

It kind of supports your statement, and is a good reason to recommend remethylation factors (methylcobalamin, folate, B6) to anyone on cycle.

Those will help manage HCY.


Also remember - blood values only tell part of the story. You can have normal B9/B12 readings but elevated HCY is often indicative of intracellular MB12 deficiency.

Yes, sure. An injection/week of vit B complex it's due on cycle.

OT: Are you Italian one ?

[hammerheart]

OT: Are you Italian one ?

Yeah typical southerner from the capital of Apulia.