300mg/wk of Test will amortize, it's the Mast that won't. For me, I found that anything over 150mg/wk (TRT dose) will increase my E2 to a point where I need an AI. 300mg/wk of Test isn't a ton but it's enough for you to take some AI to control the E2. Don't take too much AI at this Test dose or you'll crash your E2.