
Originally Posted by
GearHeaded
yeah so an AI is only going to block actual aromatization . if a drug doesn't aromatize to begin with then an AI doesn't do a thing. however, estrogen receptors and estrogenic activity are NOT dependent on aromatization. it can be activated by anything that binds to estgeon receptors and illicits such activity... like anadrol for example. it does not aromatize into estrogen. however it, all by itself apart from aromatization, can bind to estrogen receptors and illicit estrogenic activity.
also, just like a SERM like Nolva.. Nolva does not need to aromatize into estrogen in order to bind to estrogen receptors. it bypasses that whole process and binds to estrogen receptors as estrogen.
also, same with drugs like Tren and Deca. they can interact with progesterone receptors AS actual progesterone (the progestin receptors don't know that its tren that bound to it and not actual progesterone). and then through progestin activity we have the downstream effect of estrogenic activity or side effects . . and again, there is no aromatization involved in this at all. so an AI is completely irrelevant in these cases.
an AI in these cases is like having a really secure dead bolt on your front door to keep thieves from robbing you of your hard earned money ,, when in fact your money you make never enters your house, its direct deposited from your work right into your bank account online. the dead bolt on the front door doesn't do shit... you need to have a bank with good cyber security and all that tech shit.
so the only time an AI would be beneficial in these type of cases is simply to keep from adding fuel to the fire.. so lets say your running test, Deca and Anadrol and your getting some estrogenic side effects. well because of the Test being aromatized your adding more estrogen on top of the problem.. so you either need to drop the test out, or run an AI to keep from adding more fuel to the fire.