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  1. #1
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    My Estradiol pg / ml value 53.5. It’s really high.

  2. #2
    Quote Originally Posted by vic1778 View Post
    My Estradiol pg / ml value 53.5. It’s really high.
    Thats not too high.
    And you said you have been on test for 20 years at this dose?
    So what exactly changed?
    What have your levels been before?

  3. #3
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    Never really paid attention to my numbers in the past. Hypertension runs in my family. Just wondering if my body is
    More sensitive with age. I am going to do some more labs. I am suspecting the estrogen level. I got a script for Arimidex 1mg. I am going to start taking those and see. I’ve been if the testosterone for 3 weeks now and my blood pressure is steady at 120’s / 70. Lost 8 lbs of fluid in 3 weeks.

  4. #4
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    Quote Originally Posted by vic1778 View Post
    Never really paid attention to my numbers in the past. Hypertension runs in my family. Just wondering if my body is
    More sensitive with age. I am going to do some more labs. I am suspecting the estrogen level. I got a script for Arimidex 1mg. I am going to start taking those and see. I’ve been if the testosterone for 3 weeks now and my blood pressure is steady at 120’s / 70. Lost 8 lbs of fluid in 3 weeks.
    Are you saying your BP is normal when you are hypogonadal/androgen deficit and then when corrected with TRT it explodes higher? You have been on TRT 20 years without problems and suddenly cannot continue without hypertension? Have you stopped TRT in the past and seen a sudden fluid loss or BP improvement (or hypotension)? Are you ok on 75mg/wk? Post up bloodwork including E2, total test, and % free T. Do you have old bloodwork when things were normal?

  5. #5
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    I've have hypertension for may years, it runs in my family. I am on Valsartan 320 mg, Spironolactone 50 MG and Amlodipine 10 MG. I've had spikes in Blood pressure for years, but now it's more consistent and higher numbers. My Estradiol pg/ml value is 54.3, not sure if those levels are too high for me converting the Test to estrogen cause me to retain more fluid. Went to a kidney doctor, my eGFR ml/mn value is 78, my kidney doctor said my kidneys are functioning pretty good. Alt u/l = 67 AST u/l = 70 BUN/ Creatine Ratio = 16.4 Creatine = 1.22 BUN mg/dL = 20 Sodium mmol/L =140 Potassium mmol/L = 4.3 Creatine, Urine mg/dL = 73 Testosterone/ Total, SM ng/dl = 1050.

  6. #6
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    Quote Originally Posted by vic1778 View Post
    I've have hypertension for may years, it runs in my family. I am on Valsartan 320 mg, Spironolactone 50 MG and Amlodipine 10 MG. I've had spikes in Blood pressure for years, but now it's more consistent and higher numbers. My Estradiol pg/ml value is 54.3, not sure if those levels are too high for me converting the Test to estrogen cause me to retain more fluid. Went to a kidney doctor, my eGFR ml/mn value is 78, my kidney doctor said my kidneys are functioning pretty good. Alt u/l = 67 AST u/l = 70 BUN/ Creatine Ratio = 16.4 Creatine = 1.22 BUN mg/dL = 20 Sodium mmol/L =140 Potassium mmol/L = 4.3 Creatine, Urine mg/dL = 73 Testosterone/ Total, SM ng/dl = 1050.

    I still don't know why you don't try lowering your dose to see if it helps. Your serum T is 1050 ng/dL. Was that taken on a trough day? What is your free T value?

    Things just aren't adding up here.
    There are 3 loves in my life: my wife, my English mastiffs, and my weightlifting....Man, my wife gets really pissed when I get the 3 confused...
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  7. #7
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    Quote Originally Posted by vic1778 View Post
    I've have hypertension for may years, it runs in my family. I am on Valsartan 320 mg, Spironolactone 50 MG and Amlodipine 10 MG. I've had spikes in Blood pressure for years, but now it's more consistent and higher numbers. My Estradiol pg/ml value is 54.3, not sure if those levels are too high for me converting the Test to estrogen cause me to retain more fluid. Went to a kidney doctor, my eGFR ml/mn value is 78, my kidney doctor said my kidneys are functioning pretty good. Alt u/l = 67 AST u/l = 70 BUN/ Creatine Ratio = 16.4 Creatine = 1.22 BUN mg/dL = 20 Sodium mmol/L =140 Potassium mmol/L = 4.3 Creatine, Urine mg/dL = 73 Testosterone/ Total, SM ng/dl = 1050.
    Estradiol in the 50s is high, see if can't get that down a bit. You do realize Spironolactone is an anti-androgen drug (AR antagonist)? You might be able to drop that and simultaneously lower your T to something < 100mg/wk and be ok. While ref ranges are assay specific, generally 1050 ng/dL is much more than is needed; that was 2x 50mg each 100mg/wk total test cypionate? That is kind of impressive to have that high a level with so little T.

    Honestly lowering your T dosage and dropping sprionolactone might resolve hypertension and E2 issues [which are interrelated] with no other intervention, e.g. arimidex, etc.
    Last edited by powerliftmike; 01-16-2023 at 07:34 PM.

  8. #8
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    Quote Originally Posted by vic1778 View Post
    Never really paid attention to my numbers in the past. Hypertension runs in my family. Just wondering if my body is
    More sensitive with age. I am going to do some more labs. I am suspecting the estrogen level. I got a script for Arimidex 1mg. I am going to start taking those and see. I’ve been if the testosterone for 3 weeks now and my blood pressure is steady at 120’s / 70. Lost 8 lbs of fluid in 3 weeks.
    Go Easy on the anastrozole. Start low and work up, it is very effective.
    There are 3 loves in my life: my wife, my English mastiffs, and my weightlifting....Man, my wife gets really pissed when I get the 3 confused...
    A minimum of 100 posts and 45 days membership required for source checks. Source checks are performed at my discretion.

  9. #9
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    Doctor told me to take 1mg every other day.

  10. #10
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    Quote Originally Posted by vic1778 View Post
    Doctor told me to take 1mg every other day.
    1mg arimidex? Gonna get rekt on that, watch out.

  11. #11
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    Quote Originally Posted by 956Vette View Post
    1mg arimidex? Gonna get rekt on that, watch out.
    X2. Way too aggressive.
    There are 3 loves in my life: my wife, my English mastiffs, and my weightlifting....Man, my wife gets really pissed when I get the 3 confused...
    A minimum of 100 posts and 45 days membership required for source checks. Source checks are performed at my discretion.

  12. #12
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    Maybe 1 3x’s a week ?

  13. #13
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    Quote Originally Posted by vic1778 View Post
    Doctor told me to take 1mg every other day.
    You’re “dr” doesn’t know wtf he is talking about. Im done with this thread. Best of luck

  14. #14
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    Quote Originally Posted by Cuz View Post
    You’re “dr” doesn’t know wtf he is talking about. Im done with this thread. Best of luck
    I'm with you on this. I'm done playing with the troll.

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