Results 1 to 8 of 8
Like Tree2Likes
  • 1 Post By Times Roman
  • 1 Post By DOSA

Thread: Ebola & estradiol

  1. #1
    gold43's Avatar
    gold43 is offline Associate Member
    Join Date
    Feb 2014
    Posts
    404

    Ebola & estradiol

    Estradiol

    A hormone and steroid produced by woman, estradiol was found to exhibit anti-Ebola virus activity in vitro, indicating the relevance of hormonal factors and perhaps gender in susceptibility to the disease.

    A 2013 analysis entitled, “A systematic screen of FDA-approved drugs for inhibitors of biological threat agents,” detailed the findings:

    “We also identified estradiol and toremifene, two steroidal hormones, as inhibitory to both MARV and EBOV. Interestingly, these compounds have previously been identified as inhibitors of New World arenaviruses but were suggested to interfere with late stages of viral replication and assembly.”

    Another study reported:

    “Anti-EBOV activity was confirmed for both of these SERMs in an in vivo mouse infection model. This anti-EBOV activity occurred even in the absence of detectable estrogen receptor expression, and both SERMs inhibited virus entry after internalization, suggesting that clomiphene and toremifene are not working through classical pathways associated with the estrogen receptor.”

    Source Link
    http://consciouslifenews.com/theyre-...ebola/1177324/

  2. #2
    Times Roman's Avatar
    Times Roman is offline Anabolic Member
    Join Date
    May 2010
    Location
    Back from Afghanistan
    Posts
    27,376
    Maybe it's time to dose up and then go test this theory?

    Start a log.

    Day one.
    Started an estradiol cycle

    Day two.
    Exposed myself to Ebola

    Day three.
    adsfl asd asdfg

    Day four....
    aaaaaarghhhhh!
    gold43 likes this.

  3. #3
    gold43's Avatar
    gold43 is offline Associate Member
    Join Date
    Feb 2014
    Posts
    404
    ROLMFAO!!!! Looks like SERMs show anti EBOV activity too. So we can just go on and extended PCT when there is an outbreak.
    Last edited by gold43; 10-15-2014 at 08:28 AM.

  4. #4
    lovbyts's Avatar
    lovbyts is offline Knowledgeable Member
    Join Date
    Apr 2008
    Posts
    30,268
    Quote Originally Posted by gold43 View Post
    Estradiol

    A hormone and steroid produced by woman, estradiol was found to exhibit anti-Ebola virus activity in vitro, indicating the relevance of hormonal factors and perhaps gender in susceptibility to the disease.

    A 2013 analysis entitled, "A systematic screen of FDA-approved drugs for inhibitors of biological threat agents," detailed the findings:

    "We also identified estradiol and toremifene, two steroidal hormones, as inhibitory to both MARV and EBOV. Interestingly, these compounds have previously been identified as inhibitors of New World arenaviruses but were suggested to interfere with late stages of viral replication and assembly."

    Another study reported:

    "Anti-EBOV activity was confirmed for both of these SERMs in an in vivo mouse infection model. This anti-EBOV activity occurred even in the absence of detectable estrogen receptor expression, and both SERMs inhibited virus entry after internalization, suggesting that clomiphene and toremifene are not working through classical pathways associated with the estrogen receptor."

    Source Link
    http://consciouslifenews.com/theyre-...ebola/1177324/
    Im a little confused. Are they saying clomiphene and toremifene work or dont because they are different from other AIs?

  5. #5
    gold43's Avatar
    gold43 is offline Associate Member
    Join Date
    Feb 2014
    Posts
    404
    Anti EBOV activity was confirmed for both SERMS.

  6. #6
    DOSA is offline Associate Member
    Join Date
    Jan 2013
    Location
    somewhere
    Posts
    275
    i really may choose Ebola over extending any PCT
    BG likes this.

  7. #7
    GirlyGymRat's Avatar
    GirlyGymRat is offline Knowledgeable Elite ~ Respected Female Leader ~
    Join Date
    Oct 2010
    Location
    In a gym!
    Posts
    14,951
    Quote Originally Posted by Times Roman
    Maybe it's time to dose up and then go test this theory? Start a log. Day one. Started an estradiol cycle Day two. Exposed myself to Ebola Day three. adsfl asd asdfg Day four.... aaaaaarghhhhh!
    Lmao

  8. #8
    Hoggage_54's Avatar
    Hoggage_54 is offline Suspended or Banned either way gone!
    Join Date
    May 2003
    Location
    Repost
    Posts
    7,433

Thread Information

Users Browsing this Thread

There are currently 1 users browsing this thread. (0 members and 1 guests)

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •