PROOF that NON-Aromatizing steroids DON'T...

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i cant fukin spell..but for some odd reason i feel Ross was picked on in school.UP

Please refer to the avatar for "The Original Jason".for an example of someone who was picked on in H.S....that's actually him in his avatar....I would imagine he was picked on in high school (*by the other kids who were picked on)....

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there are ug's that have halo bro

Nobody that I would use...

[wolfyEVH]

Nobody that I would use...

of course

[Still Pumpin Iron]

EXACTLY...Halo is one example of a potentially great anabolic . There are dozens of lovely anabolics with various properties. To illustrate this (and their relative safety over testosterone , drol, nandrolone , tren , ect) was the purpose of my thread.

My name "PumpinIron" Just got banned...Ergo "Still Pumpin Iron"

[stupidhippo]

Did I understand sumin wrong but these werent all studies done with quite low dosages to hypopgonadal men. If so it is obvious you cant draw direct coclusions to what would happen to normal men..

[Whoisdaman]

My name "PumpinIron" Just got banned...Ergo "Still Pumpin Iron"

are you using the same computer? Id figure that they would ban your IP, obviously not.

[Still Pumpin Iron]

you posted in your Oral-T profile:

"(4-chlorodehydromethyltestosterone)
[4-chloro-17b-hydroxy-17a-methyl-androst-1,4-dien-3-one]
Molecular Weight:334.8854
Formula:C20H27O2Cl
Manufacturer: Underground Labs only
Effective Dose (Men): 10-40mgs/day
Effective Dose (Women): 5-15mgs/day
Active life: 16 hours
Detection Time: 6 weeks
Anabolic / Androgenic ratio: >100:>0 "

The effective dose for a man would begin at 20mgs, and would acceptable used up to 100mgs, though not as long. Most begin at 40mgs.

Also, where did that Ration "100:0" come from...sounds interesting..

**Active life....IV Adminstration was 16 hours...Oral admin was around 6. I'll post link..

[Still Pumpin Iron]

I GOT IT! THE TBOL STUDY THAT SHOWS IT BINDS TO SHBG AND HALF-LIFE! TAKE NOTE OF THE DIFFERENT HALF-LIFE OF IV-ADMINSTRATION VS ORAL ADMINSTRATION.
Schumann W.

Institut fur Mikrobiologie und experimentelle Therapie
(ZIMET), Jena.

Disposition and excretion of the anabolic steroid Oral-
Turinabol (1;4-chloro-17 alpha-methyl-androsta-1,4-diene-17
beta-hydroxy-3-one) were investigated in male volunteers.
Following single p.o. and i.v. administration of the tritium-
labelled compound the plasma concentration courses of total
radioactivity (1 and 1-metabolites) and of the unchanged
parent drug as well as the urinary excretion were estimated.
From these data model independent pharmacokinetic parameters
based on statistical moments were calculated. 1 is almost
completely absorbed after p.o. administration of 10 mg per
volunteer. Peak concentrations of total radioactivity and of 1
in plasma were reached about 3 h p.a. Irregularities
observed in the plasma level profile following both p.o. and
i.v. administration of 1 are due to a marked enterohepatic
circulation. Orally given 1 is subject to a first-pass
effect, resulting in a diminished systematic availability.
The AUC-ratio of the unchanged drug and the total
radioactivity of 1 : 13 shows the predominance of metabolites
in plasma. After i.v. administration the disposition of
unchanged 1 was found biphasically with a terminal half-life
of 16 h. 1 and its metabolites are preferentially excreted
via the kidneys. The urinary total radioactivity represented
about 60% of the dose following both administrations. Due to
its affinity to SHBG 1 is able to compete for the protein
binding of testosterone , resulting in an increased plasma
level of non protein-bound testosterone.


SO....

Halflife via I.V. administration 13,5 h

Halflife via oral route 16 h

Halflife of metabolites 50 -62 h

is excreted from body by renals.

has a much higher binding rate to SHBG than testosterone so it frees an amount of the test that isn't protein bound.

that amount depends on the dose ---> I read in an other study that one single dose of 40mg increases the bodys own free test levels to 4,5 times the normal concentration.

[Still Pumpin Iron]

I GOT IT! THE TBOL STUDY THAT SHOWS IT BINDS TO SHBG AND HALF-LIFE! TAKE NOTE OF THE DIFFERENT HALF-LIFE OF IV-ADMINSTRATION VS ORAL ADMINSTRATION.
Schumann W.

Institut fur Mikrobiologie und experimentelle Therapie
(ZIMET), Jena.

Disposition and excretion of the anabolic steroid Oral-
Turinabol (1;4-chloro-17 alpha-methyl-androsta-1,4-diene-17
beta-hydroxy-3-one) were investigated in male volunteers.
Following single p.o. and i.v. administration of the tritium-
labelled compound the plasma concentration courses of total
radioactivity (1 and 1-metabolites) and of the unchanged
parent drug as well as the urinary excretion were estimated.
From these data model independent pharmacokinetic parameters
based on statistical moments were calculated. 1 is almost
completely absorbed after p.o. administration of 10 mg per
volunteer. Peak concentrations of total radioactivity and of 1
in plasma were reached about 3 h p.a. Irregularities
observed in the plasma level profile following both p.o. and
i.v. administration of 1 are due to a marked enterohepatic
circulation. Orally given 1 is subject to a first-pass
effect, resulting in a diminished systematic availability.
The AUC-ratio of the unchanged drug and the total
radioactivity of 1 : 13 shows the predominance of metabolites
in plasma. After i.v. administration the disposition of
unchanged 1 was found biphasically with a terminal half-life
of 16 h. 1 and its metabolites are preferentially excreted
via the kidneys. The urinary total radioactivity represented
about 60% of the dose following both administrations. Due to
its affinity to SHBG 1 is able to compete for the protein
binding of testosterone , resulting in an increased plasma
level of non protein-bound testosterone.


SO....

Halflife via I.V. administration 13,5 h

Halflife via oral route 16 h

Halflife of metabolites 50 -62 h

is excreted from body by renals.

has a much higher binding rate to SHBG than testosterone so it frees an amount of the test that isn't protein bound.

that amount depends on the dose ---> I read in an other study that one single dose of 40mg increases the bodys own free test levels to 4,5 times the normal concentration.

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of course

Right now I'm using Stark's Primobolan and D****m's Prop and Winstrol ....

I don't use any other labs, really....I suppose I would use M-Labs and QGL, though, I just simply haven't as of yet.....

I wouldn't bother with most other UG's right now...just because of where I'm at personally and how long I've known Stark (3+ years) and D***** (same)....

[Property of Steroid.com]

I GOT IT! THE TBOL STUDY THAT SHOWS IT BINDS TO SHBG AND HALF-LIFE! TAKE NOTE OF THE DIFFERENT HALF-LIFE OF IV-ADMINSTRATION VS ORAL ADMINSTRATION.
Schumann W.
---> I read in an other study that one single dose of 40mg increases the bodys own free test levels to 4,5 times the normal concentration.

Right....but you can't extrapolate data from one study on SHBG and another on free test, and use those numbers to do your own MetaStudy...

And....that study was exactly the one I thought you were talking about....when I mentioned the Biphastic Elimination of OT...

[Still Pumpin Iron]

Right....but you can't extrapolate data from one study on SHBG and another on free test, and use those numbers to do your own MetaStudy...

And....that study was exactly the one I thought you were talking about....when I mentioned the Biphastic Elimination of OT...

Of course you can! That is science--I made an inference, and I was right. The MECHANISM by which TEST CONCENTRATIONS are increased is via an INCREASE of FREE testosterone which occurs due to Turinabols affinty to bind with SHBG.

[MatrixGuy]

Still here Ross? What you running now, cycle wise?

[wilthepill123]

sniff sniff, i smell an IP ban.

Ross, you do make valid points, oral cycles do yield some gains, however, you're missing the fact that there are other cycles that are more effective than anything you've mentioned.

Instead of wasting your time on this forum, perhaps you should seek some counseling, because you have psychopathic tendencies and features of both borderline and histrionic personality disorders. Stop starting threads only to humiliate yourself. You're a pathological liar and you need to do something to rectify that.

[Still Pumpin Iron]

Still here Ross? What you running now, cycle wise?

At the moment I am actually running Turinabol for the 1st time ever--so I am taking 40mgs ED for 6 weeks to assess its effects. I am very excited.

Yup, still here, making progress....

[Still Pumpin Iron]

sniff sniff, i smell an IP ban.

Ross, you do make valid points, oral cycles do yield some gains, however, you're missing the fact that there are other cycles that are more effective than anything you've mentioned.

Instead of wasting your time on this forum, perhaps you should seek some counseling, because you have psychopathic tendencies and features of both borderline and histrionic personality disorders. Stop starting threads only to humiliate yourself. You're a pathological liar and you need to do something to rectify that.

Number 1, I KNOW THAT THERE ARE BETTER CYCLES. You need test to be MASSIVE--however, some of us need not to be massive. These are safe alternatives that yeild nearly PERMANENT gains. I have only had success.

Number 2, I may be a Pathological Narcissist-- YES, I love myself--get over it. This thread has been completely productive. GROW UP.

[Still Pumpin Iron]

WHO THE HECK said ALL ORAL CYCLES??

This has been a HUGE misconception from the beginning...I LOVE INJECTABLES! THIS THREAD* was about NON-Aromatizing steroids and their relatively light impact on the HPTA (compared to TEST). Please review the studies that I have posted.

[MatrixGuy]

At the moment I am actually running Turinabol for the 1st time ever--so I am taking 40mgs ED for 6 weeks to assess its effects. I am very excited.

Yup, still here, making progress....

How far are you into the cycle? How does it compare to var in terms of strength gains and vascularity? Just curious.

[Still Pumpin Iron]

"As discussed in the opening section of this book, the oral use of stanozolol can also have a profound impact on levels of SHBG (sex hormone-binding globulin). This admittedly is characteristic of all anabolic /androgenic steroids , however its potency and form of administration make Winstrol ® particularly noteworthy in this regard. Since plasma binding proteins such as SHBG act to temporarily constrain steroid hormones from exerting activity, this effect would provide a greater percentage of free (unbound) steroid hormone in the body. This may amount to an effective mechanism in which stanozolol could increase the potency of a concurrently used steroid. To further this purpose we could also addition Proviron ® (1 methyl-dihydrotestosterone), which has an extremely high affinity for SHBG. This affinity may cause Proviron® to displace other weaker substrates for SHBG (such as testosterone ), another mechanism in which the free hormone level may be increased. Adding Winstrol® and Proviron® to your next testosterone cycle may therefore prove very useful,, markedly enhancing the free state of this potent muscle building androgen."


Interesting to note.

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I guess...that's all stuff I already said too....also, ross/pumpin/mindOfPumpin/stillpumpinross keep in mind I'm using active life, not 1/2 life....I find it more relevant...

[RA]

If there ever was a person I wouldnt mind bitch slapping it would be Ross.

[SwoleCat]

NOTE:

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Keep signing up here and spamming our board, you will be reported to your ISP and AOL for continual spamming abuse.

~SC~