Anybody know Pinnacle? Or Bill Roberts Personally?

**stupidhippo** · 10-08-2006, 02:18 PM

that p-450 issue has been addressed earlier.. in the other BIG thread.. it prolly aint the explanation in this case..

**GetnSwole** · 10-08-2006, 02:32 PM

ok guys I am back..... been gone for a while and I come back to see that pinn is gone? WtF happened? pinn helped me soooo much and I hate to see that he is banned, can some one pm me and let me know what the f*ck happpened.

anyway glad to be back here

**Warrior21** · 10-08-2006, 04:16 PM

Originally Posted by AnabolicAndre

I dont think that is the case cause from my research and studies I have done in pharmacokinetics, approx. 20% of all produced drugs are in one way or another affected by cytochrome p-450. TESTSTERONE is one of them.

So basically what you need to know is how to safely and temporarily supress p-450. But you cant do it all together cause c P-450 is used in many of the bodily functions.

PS. warrior I sent you a PM

Andre, just as stupidhippo said. The Cytochrome P450 system has been discussed over and over in my other thread. I've inhibitted the hell out of CYP3A4 and CYP2D6 to no avail. This problem is most likely a defect with steroid coactivators (SRC-1, SMRT,....). There are plenty of steroid coactivators. They basically start gene trnascription in the nuclei of muscle cells. Without enough coactivators you can have all the androgens you want but no muscle will be built. What I need to do is find out for sure if it's a coactivator issue or what. If it is the only drugs I know of that can help is mega dosing of Tamoxifen or Cyclohexamide.

**Warrior21** · 10-08-2006, 04:17 PM

Originally Posted by vitor

Bill Roberts holds a bachelors degree in Microbiology and Cell Science and a doctor degree in (Ph.D) in Medical Chemistry.

There is "lots" of reading materiall by Bill on the net where he goes in detail about everything you need to know about steroids. Yust do some searches...

Vitor, I've read all about Bill Roberts and his articles. I've read them. I've done all I can do. Now I need to contact him directly for more info. He does not discuss exogenous androgen resistance. Why? It's just so fkin uncommon. But maybe he knows a bit on the subject and I can have a nice chat with him.

**Warrior21** · 10-08-2006, 04:23 PM

Originally Posted by stupidhippo

i personally think they cant help u but I was just interested... I mean from a medical point of view its not very significant problem: making exo AAS work for an eugonadal male.. not gonna see many research projects on that funded.... if u happen to find someone who for some reason happens to study just that area for some reason u might get lucky.. I personally believe its pretty sure the reason for ur condition will remain unknown for quite some time.. hope im wrong though..

This is also what I'm afraid of, very afraid. But.... I have found many sites of doctors with several degrees in endocrinology, some of them are said to have specific interest in researching anabolic steroids . You know these intellectual types, I'm sure they'd be happy if I presented them with a new challenge/motivation to research something that is very uncommon. They could think of me as their next exciting science project.
Also we have gene therapy now. If I have a genetic defect in coding for steroid coactivators, it may be possible that I could undergo genetic therapy to fix this. The costs of something like this, shit I don't know.
Any of you good with genetic mutations/reparations? I know that genes repair themselves. It's possible that my brother started responding to steroids because the steroid coactivator gene repaired itself with time. I think he kind of won the lottery with a reparation like that, and I hope that in time I will too, if I can't be proactive about it.

**guest589745** · 10-08-2006, 04:26 PM

Here are articles by bill ROberts:

EDIT: Sorry, cant post a link. Or I would

**Warrior21** · 10-08-2006, 04:31 PM

Originally Posted by Skullsmasher

Here are articles by bill ROberts:

Been there, read that. They don't go into the detail I'm looking for. Thanks though Skull!

**guest589745** · 10-08-2006, 04:33 PM

There is a lot of articels there, I think it would be a good idea to email him with questions though, he seems like (If he is wiling to erspond) he would be able to help you immensely

**Warrior21** · 10-08-2006, 04:38 PM

Originally Posted by Skullsmasher

There is a lot of articels there, I think it would be a good idea to email him with questions though, he seems like (If he is wiling to erspond) he would be able to help you immensely

Yep, I don't think I saw his email in there. Lemme check again. I don't think it's there though. I think there are tons of people who can help me. You should see the stuff I'm researching now, some people are almost inhuman. Their knowledge is on a complete other level then most average people.

BG · 10-08-2006, 04:42 PM

You've gone board to board and no one is very interested, you need to see a doctor (fuc what is this the 4th time Ive said it). I will be shocked if Pinn nor Bill have time for you. Where did you come from anyway, all of sudden your like stink on shit.

**guest589745** · 10-08-2006, 04:43 PM

Originally Posted by BigGuns101

You've gone board to board and no one is very interested, you need to see a doctor (fuc what is this the 4th time Ive said it). I will be shocked if Pinn nor Bill have time for you. Where did you come from anyway, all of sudden your like stink on shit.

You dont like the thread then dont read it, yer bein a prick. Let the guy do what he wants. Youre not contributing so go find something productive to do.
Anyoen that doesnt care, doesnt have to read the damn thread.

**Warrior21** · 10-08-2006, 04:44 PM

Posted by Bill Roberts. I didnt see this first time around, but I'll be looking into this too;

"UDP-glucuronysyltransferase (UDPGT)

This enzyme attaches what is basically a sugar molecule to an –OH group of a steroid , thus deactivating it and making it far more water soluble, and more readily excreted."

**Warrior21** · 10-08-2006, 04:46 PM

Originally Posted by BigGuns101

You've gone board to board and no one is very interested, you need to see a doctor (fuc what is this the 4th time Ive said it). I will be shocked if Pinn nor Bill have time for you. Where did you come from anyway, all of sudden your like stink on shit.

Like Skull said. You don't like it, don't read it. Your mouse didn't click on this thread itself.
And besides I've said several times I need to find an endo who is roid-friendly. You accused me of being retarded in another thread. You're the one coming off as a retard right now, I told you about the whole doctor thing several times on this forum and others. Go away.

**Warrior21** · 10-08-2006, 04:47 PM

Originally Posted by Skullsmasher

You dont like the thread then dont read it, yer bein a prick. Let the guy do what he wants. Youre not contributing so go find something productive to do.
Anyoen that doesnt care, doesnt have to read the damn thread.

Priceless.

BG · 10-08-2006, 04:49 PM

Originally Posted by Warrior21

Priceless.

Very priceless, you bump your thread at M+M when only 1 thread in two days moved in front. Like said over there, get checked for aids or cancer, maybe thats the problem.

**Warrior21** · 10-08-2006, 04:53 PM

Originally Posted by BigGuns101

Very priceless, you bump your thread at M+M when only 1 thread in two days moved in front. Like said over there, get checked for aids or cancer, maybe thats the problem.

That makes perfect sense, because I'm completely natural right now and am maintaining my weight fine right? That idea right there shows your intelectual playing field I guess.
Look if you don't like me or what I post it's fine. But nobody ever forced you to check out my posts. You came in on your own accord.

**IBdmfkr** · 10-08-2006, 04:55 PM

If you can't gain naturally then there is a problem, the answer isn't anabolics.

Btw, Pinn isn't a doctor and doesn't have the tools to properly test you or your condition, I'd go see a specialist.

**Warrior21** · 10-08-2006, 04:57 PM

Originally Posted by I**mfkr

If you can't gain naturally then there is a problem, the answer isn't anabolics.

I can gain naturally. But we both know there is only so much you can do naturally. Theres plenty of guys on here who don't want other people to do steroids for "X reason", but they themselves can be guilty of that reason as well.

BG · 10-08-2006, 04:58 PM

Now answer me this, you said you've tried almost all AAS and pro-harmones , none working for you, longest being 8 weeks. Now that adds up to a pretty decent amount of $$$, but when I tell you to see a doctor you bitch like little girl its $1500. With all this $$$ be wasted, probaly more to come because your ignorant, why not go see a doctor and find the solution medically? All your going to get around here is pure speculation, no concrete answer. This is why Im acting this way. Grow up and see a doctor. PS Skull, Ill say what ever I want, even if its not productive.

**IBdmfkr** · 10-08-2006, 04:58 PM

Originally Posted by Warrior21

I can gain naturally. But we both know there is only so much you can do naturally. Theres plenty of guys on here who don't want other people to do steroids for "X reason", but they themselves can be guilty of that reason as well.

Any you still haven't listed this diet you speak of or training program..
More drugs are the answer, go for it.

**Warrior21** · 10-08-2006, 04:59 PM

I understand if he isn't a doctor. But his article on understanding androgen actions is damn impressive. Not many people mentioned steroid coactivators. I would like to pick his brain a bit at least. For someone who wants to learn more and more, I'm not seeing much encouragement. Shouldn't you guys be happy at someone's ambition to learn?

**IBdmfkr** · 10-08-2006, 05:00 PM

Pinn would tear you apart on the phone, obviously you don't know him well.. It'd be an entertaining conversation to listen to.

**Warrior21** · 10-08-2006, 05:01 PM

Originally Posted by I**mfkr

Any you still haven't listed this diet you speak of or training program..
More drugs are the answer, go for it.

The diet and training were in my other thread. I'm very very tired of discussing the adequacy of my training/diet.
I can inject 1g of testosterone and not bloat one bit. NOW if my diet and training suck, but I had 1g of test in my blood.....wouldn't I have bloat because of estrogen via 5ar conversion? Wouldn't I see side effects? This has been discussed over and over and over again in the other thread.
Do I have to post the article showing steroid resistance in here again?

**guest589745** · 10-08-2006, 05:02 PM

Originally Posted by BigGuns101

PS Skull, Ill say what ever I want, even if its not productive.

Wow, yer tough.

I take it you are having problems in your personal life and seek to let out your frustration over the internet on those who are undeserving (Impressive). I suggest you get away from the computer and solve your problem then perhaps you will be more useful, not only on the board but as a human in general.

Get well soon.

**Warrior21** · 10-08-2006, 05:03 PM

Originally Posted by I**mfkr

Pinn would tear you apart on the phone, obviously you don't know him well.. It'd be an entertaining conversation to listen to.

Let him tear me apart. I'm super confident, and can take a beating with no problem. Most normal people shit themselves when they hear me throwing around medical terms and such. If I can learn something from him it would all be worth it.

**IBdmfkr** · 10-08-2006, 05:04 PM

Originally Posted by Warrior21

The diet and training were in my other thread. I'm very very tired of discussing the adequacy of my training/diet.
I can inject 1g of testosterone and not bloat one bit. NOW if my diet and training suck, but I had 1g of test in my blood.....wouldn't I have bloat because of estrogen via 5ar conversion? Wouldn't I see side effects? This has been discussed over and over and over again in the other thread.
Do I have to post the article showing steroid resistance in here again?

You didn't go into depth with your diet/training from what I saw.. What were you stats again? Why not some pictures?

He'd be asking your the same questions as I'm asking you now that you keep avoiding bro.. he is a very good friend of mine and I speak to him daily.. He wouldn't even waste his time talking to you because you're so narrow minded.

**Warrior21** · 10-08-2006, 05:04 PM

Originally Posted by BigGuns101

Now answer me this, you said you've tried almost all AAS and pro-harmones , none working for you, longest being 8 weeks. Now that adds up to a pretty decent amount of $$$, but when I tell you to see a doctor you bitch like little girl its $1500. With all this $$$ be wasted, probaly more to come because your ignorant, why not go see a doctor and find the solution medically? All your going to get around here is pure speculation, no concrete answer. This is why Im acting this way. Grow up and see a doctor. PS Skull, Ill say what ever I want, even if its not productive.

1500 dollars was an understatement on my part. Each blood work will cost 830 dollars. Lets say it will takes at least 3 blood draws. Besides consultation fees. I'm looking at 4000 dollars. I'd have to sell my property to afford that.

BG · 10-08-2006, 05:05 PM

Originally Posted by Warrior21

I understand if he isn't a doctor. But his article on understanding androgen actions is damn impressive. Not many people mentioned steroid coactivators. I would like to pick his brain a bit at least. For someone who wants to learn more and more, I'm not seeing much encouragement. Shouldn't you guys be happy at someone's ambition to learn?

To learn............... everytime someone brings something up you have read something or find a way to poke a hole in it and thats why nobody has responded back more then once. If all you said is true, you have a medical problem, hence the need to see a doctor. Yor a fool if this is where you think your going to find your answer. I think you need attention in life and this is you ticket.

**Warrior21** · 10-08-2006, 05:05 PM

Originally Posted by I**mfkr

You didn't go into depth with your diet/training from what I saw.. What were you stats again? Why not some pictures?

Pictures, you got it damnit. I bet you guys think I'm way smaller than I am. Will be taking them right now. Wait a couple min to upload them.

BG · 10-08-2006, 05:06 PM

Originally Posted by Warrior21

1500 dollars was an understatement on my part. Each blood work will cost 830 dollars. Lets say it will takes at least 3 blood draws. Besides consultation fees. I'm looking at 4000 dollars. I'd have to sell my property to afford that.

Get a real job with insurance, you should'nt use if you cant get blood work done, I go every 4 weeks. You make yourself out to be so smart and health consious, yet you dont get blood work done.

**Warrior21** · 10-08-2006, 05:07 PM

Originally Posted by BigGuns101

To learn............... everytime someone brings something up you have read something or find a way to poke a hole in it and thats why nobody has responded back more then once. If all you said is true, you have a medical problem, hence the need to see a doctor. Yor a fool if this is where you think your going to find your answer. I think you need attention in life and this is you ticket.

I DON'T POKE HOLES IN PEOPLES SUGGESTIONS. We are having discussions. This is a discussion board. A discussion board!

**Warrior21** · 10-08-2006, 05:08 PM

Originally Posted by BigGuns101

Get a real job with insurance, you should'nt use if you cant get blood work done, I go every 4 weeks. You make yourself out to be so smart and health consious, yet you dont get blood work done.

I GOT BLOODWORK DONE TWO MONTHS AGO! Bloodwork is different from testing steroid levels though. Why are you so thick headed? Why god damnit?
Tests for androgen receptors and genetic defects cost much more. WTF is wrong with you? Fck it I hit my boiling point.

BG · 10-08-2006, 05:09 PM

Originally Posted by Warrior21

I GOT BLOODWORK DONE TWO MONTHS AGO! Bloodwork is different from testing steroid levels though. Why are you so thick headed? Why god damnit?
Tests for androgen receptors and genetic defects cost much more. WTF is wrong with you? Fck it I hit my boiling point.

Go train you might get gains.

BG · 10-08-2006, 05:11 PM

Allright Im done, save some $$$ so you can get the right test done and start growing.

**IBdmfkr** · 10-08-2006, 05:19 PM

Originally Posted by BigGuns101

Get a real job with insurance, you should'nt use if you cant get blood work done, I go every 4 weeks. You make yourself out to be so smart and health consious, yet you dont get blood work done.

Don't get upset but it's nice to see what we're working with if we are to make any suggestions.. since none are doctors here we could possibly help you obtain gains in other ways than overdosing drugs.

Just maybe.

Btw, don't forget the diet LMAO

**Hellmaskbanned** · 10-08-2006, 05:31 PM

Originally Posted by Warrior21

I GOT BLOODWORK DONE TWO MONTHS AGO! Bloodwork is different from testing steroid levels though. Why are you so thick headed? Why god damnit?
Tests for androgen receptors and genetic defects cost much more. WTF is wrong with you? Fck it I hit my boiling point.

You do respond to steroids , cuz that anavar is kicking in and your roid raging.

**AnabolicAndre** · 10-08-2006, 06:11 PM

warrior is a goood guy, all he wants is to learn. He and skull have done so much research and came to a conclusive hypothesis as well as ruled out some other possible problems. theyre just looking for someone to possibly give them some insight.

**SnaX** · 10-08-2006, 06:26 PM

Originally Posted by rake922

I wanted his actual name so I could google it... Then view his pics

If I can't... I'll live

Damn...

**stupidhippo** · 10-08-2006, 10:39 PM

bigguns - the advise to see a doctor is pointless in this case... they dont know about these stuff, this isnt a major medical concern... they odnt teach this stuff in school and what he is trying to find out prolly no-one in the world knows for sure. He might get lucky with some specialist who has an interest in the field but even that is very unlikely. I am one year away of being able to work as a doctor so I should have a pretty good idea on what they know on general level..

**Warrior21** · 10-08-2006, 10:58 PM

Originally Posted by stupidhippo

bigguns - the advise to see a doctor is pointless in this case... they dont know about these stuff, this isnt a major medical concern... they odnt teach this stuff in school and what he is trying to find out prolly no-one in the world knows for sure. He might get lucky with some specialist who has an interest in the field but even that is very unlikely. I am one year away of being able to work as a doctor so I should have a pretty good idea on what they know on general level..

I've found some amazing people over the internet. Their studies are insane. All of the coactivators, actylators, genes I am studying right now are connected to each other. There are molecular endocrinologists with degrees in pharmacology who I bet would be able to help me out. Now for them to actually help me out would be a completely different story.