"cleaning" out your receptors, but for sleepinng aids

[bor]

THe ways we use ketotifen for epfedrine and clen , is there a way to clean out you receptors responsible for sleeeping aids duch as ambien, some sort of benzos or whatever...

[magic32]

Good question!

The answer is "no", and the reason is because both Ambien's action site and mechanics are rather unique. It works in combination with the neurotransmitter Gaba (one of 18 major brain chemicals that control communication among neighboring brain cells).

Once GABA is discharged it dampens the electrical activity of neighboring brain cells. Laboratory studies have shown that Ambien works with Gaba to further reduce the possibility of certain brain cells becoming electrically active. Thus, unlike older sleep drugs, Ambien targets a specific area of the brain cell causing it to rapidly knock you out.

For the technical version see Clinical Pharmacology 12:
http://products.sanofi-aventis.us/ambien/ambien.pdf

[naturalsux]

Good question!

The answer is "no", and the reason is because both Ambien's action site and mechanics are rather unique. It works in combination with the neurotransmitter Gaba (one of 18 major brain chemicals that control communication among neighboring brain cells).

Once GABA is discharged it dampens the electrical activity of neighboring brain cells. Laboratory studies have shown that Ambien works with Gaba to further reduce the possibility of certain brain cells becoming electrically active. Thus, unlike older sleep drugs, Ambien targets a specific area of the brain cell causing it to rapidly knock you out.

For the technical version see Clinical Pharmacology 12:
http://products.sanofi-aventis.us/ambien/ambien.pdf

will it help if you take GABA?

[magic32]

will it help if you take GABA?

Help what?
Ambien doesn't downgrade anything by virtue of not working at the receptor level, so what's there to help? There are virtually no sides and it's been proven safe and effective for long-term administration.

However, barring physiological deficiencies that require long or lifetime therapies, one's goal should always be towards weaning off all drugs.

[bpm1]

damn magic32 u do know ur s**t!! r u a pharmacist or what?