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  1. #41
    devildog1967's Avatar
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    thanks ..sorry for being thick...lol

  2. #42
    AnabolicBoy1981 is offline Anabolic Member
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    Quote Originally Posted by gdevine;5***019

    Just remember, high E2 causes all kinds of very bad things like down-regulation of your androgen receptors which will make your test ineffective as there will be less of these recpetors to make test work for you.

    Also, high E2 causes Hypothyroidism...not good at all.
    Ok..where on gods earth did you read this?? I have never seen anything to support that and only to the contrary. Estrogens generally help make more androgen receptors and increase glut-4 activity and carbohydrate uptake. That's why generally guys will report gaining more after doing a cycle with no ai, even if its lower dosed. I certainly can attest to higher estrogen levels producing more results, muscle wise. Not to mention its not an accident that they put estrogen in cattle implants, because they know it makes them grow more. Now TRT wise we obviously dont want that because it will be hard as hell to get boners, lose or maintain low-ish bodyfat, and also the implications on slowing thyroid, which i agree with. But GDEVINE where did you hear the estrogen will cause downrgulation of androgen recpetors that's my main question.

    To the OP i think it's odd that you had a e2 level THAT high from a mere 100mg of test. id have to take 500-600mg to get that high honestly but you are you. So yeah YOU might need a full mg of adex but generally for most ppl i would NOT recomend a full mg for a mere 100mg of test. Who made that rule?

  3. #43
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    Quote Originally Posted by AnabolicBoy1981 View Post
    Ok..where on gods earth did you read this?? I have never seen anything to support that and only to the contrary. Estrogens generally help make more androgen receptors and increase glut-4 activity and carbohydrate uptake. That's why generally guys will report gaining more after doing a cycle with no ai, even if its lower dosed. I certainly can attest to higher estrogen levels producing more results, muscle wise. Not to mention its not an accident that they put estrogen in cattle implants, because they know it makes them grow more. Now TRT wise we obviously dont want that because it will be hard as hell to get boners, lose or maintain low-ish bodyfat, and also the implications on slowing thyroid, which i agree with. But GDEVINE where did you hear the estrogen will cause downrgulation of androgen recpetors that's my main question.

    To the OP i think it's odd that you had a e2 level THAT high from a mere 100mg of test. id have to take 500-600mg to get that high honestly but you are you. So yeah YOU might need a full mg of adex but generally for most ppl i would NOT recomend a full mg for a mere 100mg of test. Who made that rule?
    1mg AI per 100mgs test is a general rule, all is based on the individual. not an expert on your remarks regarding high E2, but i was told and i hope i can reward it correctly. if E2 is too high the test binds to the sex hormone, you can have 2000 test level in your blood but if your E2 is high and causing test to bind to the sex hormone (binding globulin) you'll end up with low free test and therefore useless! i hope i said that correctly!
    Last edited by bass; 10-23-2011 at 09:54 PM.

  4. #44
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    All i know is that my E2 was that high and all i was waiting for is my cock to drop off and i grow a fanny. None of us are doctors and know the correct dosage but i take advice from people that have been there and done it. I feel 100 times better, and one thing i do know is the health damage that can be caused by too much E2. Blond moment gone.

  5. #45
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    It wasn't a blond moment. It was your damn traps momentarily cutting off blood flow to your brain!


  6. #46
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    update
    done 1mg friday .5 sunday not feeling at my best(MOODS ARE NOT GOOD AND SNAPPY)..maybe took E2 to low ..but cant really see that it would.
    Plus side ... Lost 2k weight so must of been bloat .. need to keep pulling my trousers up..lol

  7. #47
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    Quote Originally Posted by devildog1967 View Post
    update
    done 1mg friday .5 sunday not feeling at my best(MOODS ARE NOT GOOD AND SNAPPY)..maybe took E2 to low ..but cant really see that it would.
    Plus side ... Lost 2k weight so must of been bloat .. need to keep pulling my trousers up..lol
    I doubt it would have dropped your E2 so low that you have neg sides already. AI's can work fast but not that fast...unless of course you are ultra sensitive to AI's and there are some men who are.

    Losing 2k is probably just the water retention and a sign that it's working.

    Keep an eye on all low sides of E2. Erection quality is one of the best indicators; like you can't get a 100% erection or worse. Orgasm quality is another.

    Keep us posted Devildog.

  8. #48
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    yes and give your body time to adapt because other hormones are adjusting as well!

  9. #49
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    Thanks GD and BASS..

  10. #50
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    Still feel shit sex drive gone again , So it was in my mind..lol. Feel like stopping the whole thing

  11. #51
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    sorry to hear bro

    remind please...any probs at all before TRT?

  12. #52
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    thats too bad, if you were taking care of properly you would have never gone through this! it sucks this treatment is not offered in UK!

  13. #53
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    Quote Originally Posted by jpkman View Post
    sorry to hear bro

    remind please...any probs at all before TRT?
    depression..On shed loads of meds for that which with TRT i was able to come off completely..even tho self medicated TRT. Sex drive had been rock bottom for 20Y.. was great for 16 weeks on TRT. the list goes on.. Doc here gave me no help what so ever just slated me for helping myself . Now that the E2 is sky high its all gone tits up. And again doc will not back me on jack shit .. even to the point of now refusing blood tests . Depression is also creeping back now .. Oh what joy ...lol ..I cant afford private blood tests . So bottom line is to stop all as i dont want to keep flying blind as my heath might suffer more ..

    Thanks guys for all your help on this .

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    Christ my heart goes out to you man. It's frustrating to all of us here in the community as we all try to help each other out and when we see a crisis like yours it breaks our heart.

    Please keep us posted on any new development and don't give up HOPE!


    gd

  15. #55
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    thanks GD

  16. #56
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    Quote Originally Posted by gdevine View Post
    Christ my heart goes out to you man. It's frustrating to all of us here in the community as we all try to help each other out and when we see a crisis like yours it breaks our heart.

    Please keep us posted on any new development and don't give up HOPE!


    gd
    x2

    i know i give a lot of credit to TRT but i do at times remind that hormones arent the fix all /end all...i'm sure u know that...just sayin

    i also cant afford bloodwork and at times am not 100%..

    i hope u get to the bottom of this bro

  17. #57
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    Stick with the AI a little longer bro, you haven't been on long enough.

  18. #58
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    good call jd

  19. #59
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    I am keeping on with it a bit longer as JD says i perhaps have not given the AI long enough .

  20. #60
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    Just to add.. Iv took my test back up to 200mg as thats when i was at my best . I think its just the playing around game to find the sweet spot

  21. #61
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    [QUOTE=AnabolicBoy1981;5784927]Ok..where on gods earth did you read this?? I have never seen anything to support that and only to the contrary. Estrogens generally help make more androgen receptors and increase glut-4 activity and carbohydrate uptake. That's why generally guys will report gaining more after doing a cycle with no ai, even if its lower dosed. I certainly can attest to higher estrogen levels producing more results, muscle wise. Not to mention its not an accident that they put estrogen in cattle implants, because they know it makes them grow more. Now TRT wise we obviously dont want that because it will be hard as hell to get boners, lose or maintain low-ish bodyfat, and also the implications on slowing thyroid, which i agree with. But GDEVINE where did you hear the estrogen will cause downrgulation of androgen recpetors that's my main question.

    Estrogen down-regulation of androgen receptors.

    In summary.

    Estradiol treatment caused a reduction in androgen receptors, and estradiol withdrawal lead to a rise in androgen receptors. We believe that these results provide a mechanism whereby estradiol may directly antagonize androgen action. Conversely, estradiol withdrawal may potentiate androgen action by allowing androgen receptor levels to rise. This hypothesis may help explain the basis of the estrogen/androgen ratio as a predictor of sex steroid response.

  22. #62
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    UPDATE

    Well guys i took it back to 200mg and 1mg(SPLIT INTO TWO) of dex per week and all seems good again. I will attempt to drop back to 150mg a week to see if im ok on that as i dont really want to run at 200mg for too long .

    Its all trial and error .

  23. #63
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    Best of luck with it bro

  24. #64
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    Quote Originally Posted by devildog1967 View Post
    UPDATE

    Well guys i took it back to 200mg and 1mg(SPLIT INTO TWO) of dex per week and all seems good again. I will attempt to drop back to 150mg a week to see if im ok on that as i dont really want to run at 200mg for too long .

    Its all trial and error .
    yes good luck, but based on your previous E2 levels 1mgs AI may not be enough for 200mgs of test! are you planing to do blood work later on?

  25. #65
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    Not stopping on 200mg going back to 100-150mg. im still waiting for the docs to get back to me to see if they will help me. They will not do bloods for 12 months unless they start to back me. So its a waiting game for me .

  26. #66
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    So your on test therapy, my doctor has me on too. My test levels are 150ng/ml naturally he wants at 300-400ng/ml. I was on test E at 100mg a week but after 10-12 weeks started to get sides from!! Should I use an AI like you are?

  27. #67
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    By the way I felt better at 200mg a week also, my doctor prescribed and does my blood test, took me seeing him for a year and a half to help me!!

  28. #68
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    Quote Originally Posted by FONZY007 View Post
    By the way I felt better at 200mg a week also, my doctor prescribed and does my blood test, took me seeing him for a year and a half to help me!!
    Oh christ i feel tonnes better.. but at the mo i self medicate because uk docs are wank..lol

    Glad your all sorted buddy

  29. #69
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    Quote Originally Posted by FONZY007 View Post
    So your on test therapy, my doctor has me on too. My test levels are 150ng/ml naturally he wants at 300-400ng/ml. I was on test E at 100mg a week but after 10-12 weeks started to get sides from!! Should I use an AI like you are?
    If you look at my E2 readings they are way high on lowish dose of test.. im now taking 1mg of dex split into 2 . so i would say you do need it as its as bad as having low test levels.

  30. #70
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    update

    Changed to 75mg twice a week with .5 dex twice a week.
    So far all is good in the world of the devildog.

  31. #71
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    Quote Originally Posted by devildog1967 View Post
    update

    Changed to 75mg twice a week with .5 dex twice a week.
    So far all is good in the world of the devildog.
    thanks bro and glad...hope continues...

  32. #72
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    Finally i have my first appointment with a endo..took loads of pushing my doctor, but hey ho i got there ..roll on the 17th of this month.

    looks like they are going on my symptoms and not my levels ...

  33. #73
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    I found one problem !! when i take my .5 dex i get a bit down for 24h then im good again.. So im going to drop down too .25 twice a week.

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