Could a high SHBG number cause a crash?

**2Sox** · 02-22-2013, 02:29 PM

My lab results before my very first test cyp shot was:
Total: 240 ng/DL
Free: 38 pg/mL
SHBG: 54 nmol/L

I crashed badly three days after the shot. Could this SHBG number have been the cause of it? It's now the eigth day and kind of dragging my butt.

**steroid.com 1** · 02-22-2013, 02:37 PM

Please edit your post and add ranges.

To answer your question; yes it is possible.

Remember, SHBG attaches to the androgen receptor sites rendering Testosterone useless.

What we would really need to see is Free Testosterone, this would tell us the truth.

**HRTstudent** · 02-22-2013, 02:54 PM

If anything, high SHBG would delay the crash. SHBG extends the half life of testosterone in the body. People with low SHBG typically need to dose more frequently.

Regardless, it's been one week... that's not enough time to judge anything. As hard as it is, have patience. Journaling helps a lot, and really puts things into perspective down the road.

**2Sox** · 02-22-2013, 02:58 PM

gdevine,
Not sure what you mean by ranges. Did you mean lab units? Edited that above. Could you expand on your answer? Thanks.

**2Sox** · 02-22-2013, 03:02 PM

HRT,
Thanks for the encouragement. I've been on TRT continuously since July using various deliveries - patches, Testopel, Androgel . I had stopped the Androgel for three days before this shot of test cyp and this was my reaction. I was really disturbed by it and and not a little surprised!

**steroid.com 1** · 02-22-2013, 03:54 PM

Originally Posted by 2Sox

gdevine,
Not sure what you mean by ranges. Did you mean lab units? Edited that above. Could you expand on your answer? Thanks.

Yes, on your blood work you will see the range for each lab to the far right of the report.

**steroid.com 1** · 02-22-2013, 03:55 PM

Originally Posted by 2Sox

HRT,
Thanks for the encouragement. I've been on TRT continuously since July using various deliveries - patches, Testopel, Androgel. I had stopped the Androgel for three days before this shot of test cyp and this was my reaction. I was really disturbed by it and and not a little surprised!

What is your weekly protocol?

**HRTstudent** · 02-22-2013, 04:23 PM

Originally Posted by 2Sox

HRT,
Thanks for the encouragement. I've been on TRT continuously since July using various deliveries - patches, Testopel, Androgel. I had stopped the Androgel for three days before this shot of test cyp and this was my reaction. I was really disturbed by it and and not a little surprised!

Definitely give it time to work. And don't be afraid to titrate down before you up the dose. More and more, I'm reading about people who are feeling better when they lower the dose. Most importantly, give things time to work. Measure things in weeks as opposed to days.

**2Sox** · 02-22-2013, 05:41 PM

Reference Interval
TESTOSTERONE , TOTAL 240.00 NG/DL 175.00-781.00
TESTOSTERONE, FREE 33.37 PG/ML 47.00-244.00
SHBG 54.10 nmol/L 10.00-57.00

First shot: 400mg. Protocol: Every two weeks. (I posted this on another thread.)

I'm surprised that I haven't had as fast a response to cyp as I did to the patches, pellets and gels. (My total went up to 1100 in two weeks on Testopel.) I'm sticking with the shots, though.

**Trific** · 02-22-2013, 06:37 PM

I've watched all your doc's videos....I believe he's probably helped alot of people get started with TRT...we just believe we have a more modern way of getting the body a more level flow of test when doing injections and we believe less test more often is better because it creates less sides.

Any chance in your doc letting you self inject?

**kelkel** · 02-22-2013, 06:58 PM

You're kidding about the 400mg shot I hope?

**2Sox** · 02-22-2013, 07:06 PM

Kelkel,
You're kidding about your question, I hope?

Humor is good in the right place. I wouldn't kid when asking this question.

Trific,
I'm seeing that what you speak of is the present approach. I'd like to self inject. I have to find a doc who accepts insurance around here. NYC is filthy with Bio identical Park Avenue docs who want the cash up front. Gordon accepts all insurance - Medicare included.

**HRTstudent** · 02-23-2013, 04:07 AM

400mg every 2 weeks is a pathetic TRT protocol to be on. It's as if a doctor prescribing that has not read anything on male TRT in the last decade, nor do they attend any lectures or conferences on the matter...

**2Sox** · 02-23-2013, 06:56 AM

HRTStudent,
Yes, several have responded similarly. There is a sticky on this forum, originally posted in 2004, (Tulane University) that perhaps someone should footnote with updated information on present accepted dosing. It recommends 200-300mg every two to three weeks and higher. I guess he feels that his patients should be treated with the the higher doses. I'll have to have a discussion with him about what I have been learning on this forum and from other sources.

I think I'll request a 200mg weekly injection the next time I see him. Would you recommend that? I don't think he goes for self injecting.

**steroid.com 1** · 02-23-2013, 09:21 AM

I know, there are stickies in here that are outdated...we have come a long way in here to update the stickies but there's more work to be had...

**steroid.com 1** · 02-23-2013, 09:24 AM

Originally Posted by 2Sox

HRTStudent,
Yes, several have responded similarly. There is a sticky on this forum, originally posted in 2004, (Tulane University) that perhaps someone should footnote with updated information on present accepted dosing. It recommends 200-300mg every two to three weeks and higher. I guess he feels that his patients should be treated with the the higher doses. I'll have to have a discussion with him about what I have been learning on this forum and from other sources.

I think I'll request a 200mg weekly injection the next time I see him. Would you recommend that? I don't think he goes for self injecting.

200 mg at one time is a lot...you'd be better served at 100 mg twice a week to control E2.

BTW, 200 mg a week is a very large dosage. Some of the best TRT practitioners are getting great results at 60 to 80 mg per week.

Why so much?

**2Sox** · 02-25-2013, 12:31 PM

gdevine,
Sorry for the long delay. Have to keep better tabs of the forum. I don't have to go with 200 mg a week if some other dose would work better. I'd love to self inject. I'll be seeing the doc on Thursday and see what he says. If he'll go for injecting me with 100 mg and giving me a syringe to take home until the following week - that would be good. He's my new doc so I'll have see what we can both work out.

What dosing protocol seems to be working for people on the forum?