Aromatase Deficiancy

**kelkel** · 06-12-2013, 07:03 PM

Guys,

I saw someone mention he has this syndrome recently and thought I'd post it here instead of on that particular thread. Interesting read if you're so inclined.

Kel

Journal of Clinical Research in Pediatric Endocrinology

**100%** · 06-12-2013, 07:53 PM

This guy must have felt like shi* estrogen was undetectable took a heavy toll on his bones also.

**Java Man** · 06-12-2013, 07:57 PM

Not the usual problem we hear about daily is it? Interesting. Thanks kelkel.

**JohnnyVegas** · 06-12-2013, 08:00 PM

That is fascinating.

Sometimes I wonder what people think when they look at their Google analytics and see a bunch of us reading their stuff.

**kelkel** · 06-12-2013, 08:04 PM

Originally Posted by 100%

This guy must have felt like shi* estrogen was undetectable took a heavy toll on his bones also.

I crashed my E2 once when I was starting out in TRT with a crap doc. Felt horrible.

Originally Posted by JohnnyVegas

That is fascinating.

Sometimes I wonder what people think when they look at their Google analytics and see a bunch of us reading their stuff.

Better yet, what's the NSA think! Ha!

**100%** · 06-12-2013, 08:08 PM

Estrogen was undetectable....Wonder if it was a sensitive assay lol!

**100%** · 06-12-2013, 08:15 PM

II. Estrogen levels as determined by an ultrasensitive bioassay. J Clin Endocrinol Metab 1996;81:3203-3207

**bass** · 06-13-2013, 11:38 AM

good read Kel! this might explain allot of my recent symptoms due to crashed E2!

**38onTRT** · 06-13-2013, 02:41 PM

Ive done the same, crashed E2 is no bueno.. A bit of Test Prop takes care of it in a day or so....

**kelkel** · 06-13-2013, 06:17 PM

This adds to it a bit and is a good article overall. Specifically this part: Phenotype of aromatase deficiency and excess:

Aromatase inhibitors in men: effects and therapeutic options

**100%** · 06-14-2013, 06:43 AM

Originally Posted by kelkel

This adds to it a bit and is a good article overall. Specifically this part: Phenotype of aromatase deficiency and excess:

Aromatase inhibitors in men: effects and therapeutic options

I found this part very interesting as there has been a lot of talk about what healthy levels really are. Proposed a threshold for bioavailable estradiol of 30 pM, below which BMD appeared to be strongly and negatively associated with the plasma bioavailable estradiol concentration in men.