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Thread: HCG - 250 vs 500

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    Lockout888 is offline Associate Member
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    Arrow HCG - 250 vs 500

    Are there any benefits to taking HCG 500iu vs 250iu (3 times per week)?

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    I'm interested in finding this out as well..

    I always hear guys doing 500iu 2x week but what about those sensitive to estrogen spikes... Wouldn't 250iu 2-4x week keep e levels more stable?

    Nice post op

  3. #3
    100%'s Avatar
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    Dr crisler is saying the best way is 100 iu's of hcg subq daily to start work up from there if needed. So what ever works for you with time effort reaction wise.

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    bluskiblacdeth is offline Junior Member
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    just me personally here.... I started at 1000iu 3 x week for 2 weeks then backed off to 500iu 3x week per my docs instructions. after one month, I backed it off to 250iu 3 x week and started to feel crappy. Upped back up to 500iu and bounced back to feeling good. I will say that I am somewhat battling some e2 issues lately though, need to get in for blood work.

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    i think I'm gonna stick with 500iu EOD since that seemed to work out great for everyone in that study that's posted in the HCG sticky. Or maybe just M/W/F to keep it simple.

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    ^^Beautiful dog. Yours?

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    is there a certain iu level that needs to be used weekly to keep the boys fresh?
    ex: 700-100iu's total per week?

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    Quote Originally Posted by APIs View Post
    ^^Beautiful dog. Yours?
    Nah, I wish man...stuck with two cats for the moment!

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    100%'s Avatar
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    Quote Originally Posted by Keep_It_Moving View Post
    is there a certain iu level that needs to be used weekly to keep the boys fresh?
    ex: 700-100iu's total per week?
    The least amount that works for you.
    Java Man likes this.

  10. #10
    ZenFitness is offline Associate Member
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    For me it seems the best is in between 750 - 1000 IUs/wk. I usually do 250 3x a week, but occasionally a 4th is nice.

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    Quote Originally Posted by 100% View Post
    The least amount that works for you.
    This....
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    I respond better to a larger dose e3d vs eod or ed on a continuous, equally-dosed timeline. Better in the sense that my nuts feel harder, fuller, and hang lower. Libido increase is also more pronounced.
    Last edited by Blitz777; 07-08-2013 at 11:04 AM.

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    crap can't delete this post

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    Quote Originally Posted by Blitz777 View Post
    I respond better to a larger dose e3d vs eod or ed on a continuous, equally-dosed timeline. Better in the sense that my nuts feel harder, fuller, and hand lower. Libido is also increased.
    I'm a little confused about this - how do we measure "what works best" for you? Is it as Blitz mentions above? What are the standards?

    I've tried various protocols from 100iu ED up to 250iu ED and various doses and days in between. I felt the same on all of them. My libido is okay, my stones hang low but haven't enlarged past a certain point. Is it nut size and degree of horniness that you measure to find out what works for you? LOL. How do you know what's best? Maybe I should up my dose to over 250iu ED to see if could grow a couple the size of premium lemons? Probably not a good idea because I'd be walking funny. ;-)

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    I currently take 250iu every Mon, Wed & Fri but felt like I had more energy taking 400iu twice a week, 1 day prior to test injections. I just assumed this was causing my high E2 levels, but I'm starting to re-consider since my E2 levels never dropped with the newer protocol.

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    Quote Originally Posted by FRDave View Post
    I currently take 250iu every Mon, Wed & Fri but felt like I had more energy taking 400iu twice a week, 1 day prior to test injections. I just assumed this was causing my high E2 levels, but I'm starting to re-consider since my E2 levels never dropped with the newer protocol.
    That's interesting. A few days ago, I just dropped to 250iu EOD and today I feel I don't need my Adex dose (.25mg E3D). Not a scientific finding but maybe dosing hCG ED spikes up my E2 to where I can feel it. What do you think?

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    FRDave's Avatar
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    Quote Originally Posted by 2Sox View Post
    That's interesting. A few days ago, I just dropped to 250iu EOD and today I feel I don't need my Adex dose (.25mg E3D). Not a scientific finding but maybe dosing hCG ED spikes up my E2 to where I can feel it. What do you think?
    It's possible but hard to say. In the past 7 weeks I have got my E2 levels down from 75 to 45 (still high), yet I can not feel any difference lol. Maybe once in range (mid 20's to lower 30's) I would be able to tell the difference vs out of range, but since I have been out of range from the get go, I can't make a comparison and have to base my judgement on lab work.

    I may switch back to twice weekly injections of HCG for simplicity as I don't think it affected my E2 levels... still deciding.

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    crashfirepm53 is offline Associate Member
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    250iu twice a week and I still feel like crap. Ill try 500iu 2x wkly for a few weeks.

  19. #19
    dreadnok89 is offline Member
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    Don't forget dudes if your primary hcg will do nothing for you. I have noticed nothing on it. And I noticed when my estrogen was 15 to 20 I felt great!

  20. #20
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    Quote Originally Posted by dreadnok89 View Post
    Don't forget dudes if your primary hcg will do nothing for you. I have noticed nothing on it.
    This is the part that's hard to get past. So while on clomid for 6 months, my test was 300ng/dl highest. There is some test being made by the testes, right? So at a minimum, even if I am primary and can only produce 300ng/dl, hCG should help some? If I am primary, will this preclude me from creating sperm (azoospermia) with hCG? My main hope is that hCG will help me keep some sperm production going. I think getting hMG will be an uphill battle royal.

  21. #21
    ZenFitness is offline Associate Member
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    hCG 3X a week made a big difference for me as a supplement to my TRT. I felt better with just test cyp but hCG kicked it up a couple of notches.

    If it's working (assuming you are on TRT) then you should notice you'll get a scrotum back and your nuts get larger. Way more comfortable and my libido went up a bit to boot.

  22. #22
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    Quote Originally Posted by roxer View Post
    This is the part that's hard to get past. So while on clomid for 6 months, my test was 300ng/dl highest. There is some test being made by the testes, right? So at a minimum, even if I am primary and can only produce 300ng/dl, hCG should help some? If I am primary, will this preclude me from creating sperm (azoospermia) with hCG? My main hope is that hCG will help me keep some sperm production going. I think getting hMG will be an uphill battle royal.
    hCG had a very positive effect on me. My scrotum came back and my stones got firmer and larger but never returned to normal - and I've been using it since March. I started hCG about 9 months into TRT and my nuts really shrunk during that time. My urologist never bothered to test me for primary or secondary and I didn't know enough at the time to even ask. Things are different now. As I'm 65, and have no other health issues at all, I'm assuming I'm both primary and secondary to a degree. It's my understanding that this is possible.

    A very important benefit for me is that hCG makes for very good, normal orgasms. When I was on TRT before taking hCG, I felt something was definitely missing; wasn't like before. As soon as I started hCG, I felt the difference immediately.

    Now regarding sperm production, I understand that hCG definitely helps. But if you really want to conceive, you should take hMG - which stimulates the Sertoli cells that are responsible for sperm production. Fertility clinics prescribe it and it's expensive, but if you want children this would help matters. If you really searched, you'd be able to get it overseas. It's called hMG Massone - the manufacturer. I'd advise against buying a no name from China.

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    roxer's Avatar
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    Saw that on google, thanks very much. I'm not too good with ampoules. Now to find a place that's not going to rip me off.

  24. #24
    Trific's Avatar
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    Here's one place, but I've probably seen 6 places so far:

    purepeptide.com/#/hmg/4537585717

  25. #25
    pjbandit is offline Junior Member
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    How much hmg while on trt? Is there a protocol?

    Will you have to run it the entire time on trt?

  26. #26
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    Quote Originally Posted by Trific
    Here's one place, but I've probably seen 6 places so far:

    purepeptide.com/#/hmg/4537585717
    Thanks much Trific. Looks like they have some decent stuff. Anyway to know if it is legit?

  27. #27
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    Quote Originally Posted by pjbandit
    Will you have to run it the entire time on trt?
    If you want to be able to make babies, yes... I'm thinking about it to keep my cells stimulated. Maybe do it once and a while? Not sure.

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    Quote Originally Posted by roxer View Post
    Thanks much Trific. Looks like they have some decent stuff. Anyway to know if it is legit?
    Wouldn't HMG increase the fsh signal? If so, then before and after fsh labs.

  29. #29
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    Quote Originally Posted by roxer View Post
    Saw that on google, thanks very much. I'm not too good with ampoules. Now to find a place that's not going to rip me off.
    You're welcome. Actually, Triffic first made me aware of the Massone brand of hMG. I then looked into it further. No matter where I searched, it always came out expensive. The cheapest somewhat legit place I found was $22 a shot. And it's my understanding that one should take a minimum of two shots a week - 3 for maintenance is better. That could run big bucks for a lifetime.

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    Quote Originally Posted by dreadnok89 View Post
    Don't forget dudes if your primary hcg will do nothing for you. I have noticed nothing on it. And I noticed when my estrogen was 15 to 20 I felt great!
    Correct to a point.

    HCG has neurological benefits as well. There are LH receptors throughout your body and in your brain.
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  31. #31
    dreadnok89 is offline Member
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    Quote Originally Posted by kelkel View Post
    Correct to a point.

    HCG has neurological benefits as well. There are LH receptors throughout your body and in your brain.
    OK, I just meant effect to your testes. Maybe I just don't mix mine right. And you can still produce sperm with low T. I know I did.

  32. #32
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    Quote Originally Posted by dreadnok89 View Post
    OK, I just meant effect to your testes. Maybe I just don't mix mine right. And you can still produce sperm with low T. I know I did.
    You are correct. Mine never did come back to normal size due to the damage done from basically being shut down via a tumor. Flip side is smaller nuts make other items close by look bigger. Lose - win thing.
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    oops! wrong thread.
    Last edited by OLDANDWEAK; 07-09-2013 at 08:58 AM.

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    Quote Originally Posted by kelkel View Post
    You are correct. Mine never did come back to normal size due to the damage done from basically being shut down via a tumor. Flip side is smaller nuts make other items close by look bigger. Lose - win thing.
    Always a tradeoff in life

    Hey kelkel, have you noticed a difference in quality or effectiveness from hCG sources? My first batch was name-brand (App) and my second batch was compounded at the pharmacy (saves me $150 a pop). So far I think everything is the same, but curious about your (or anyone else's) experience. I'm not referring to some non-prescription overseas hCG... this is legit prescription stuff domestic in the US.

  35. #35
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    No, mine's always the same scripted stuff.
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    ImpeccableChaos is offline Junior Member
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    Quote Originally Posted by kelkel View Post
    You are correct. Mine never did come back to normal size due to the damage done from basically being shut down via a tumor. Flip side is smaller nuts make other items close by look bigger. Lose - win thing.
    I have been on TRT for 5 -6 yrs. I just started HCG about 6 weeks ago 250iu twice a week. Mine have gotten a little bigger but not as big as before and I don't mind really. It's just that they had gotten tiny for goodness sake!. Do you think 5 yrs is too long for them to return to normal? And should I up thre dose of HCG?

  37. #37
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    I need to read this thread, but thought I'd respond. I recently bumped my hCG dose from 200iu 3X to about 500iu 3X. I feel better as a result, and was sort of surprised to have that happen. I'm going to continue on that way for a while and see what happens.

    My current testosterone dose if Androgel 1.6%, 4 pumps daily.

  38. #38
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    Quote Originally Posted by ImpeccableChaos View Post
    I have been on TRT for 5 -6 yrs. I just started HCG about 6 weeks ago 250iu twice a week. Mine have gotten a little bigger but not as big as before and I don't mind really. It's just that they had gotten tiny for goodness sake!. Do you think 5 yrs is too long for them to return to normal? And should I up thre dose of HCG?
    I don't think you'll get to "normal" on 250 iU a week. When I ran 250 iU every day it seemed to be close, but that is quite a bit of hCG IMO. I'd rather sacrifice a little size and keep my E2 in check. That said, there are days that the family jewels seem to shine like they used to in terms of size... nuts seem to oscillate a bit in size at different times of the day and different days of the week.
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  39. #39
    ZenFitness is offline Associate Member
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    To clarify... nuts can get to about their former size, but the scrotum doesn't hang anywhere near as low. As kelkel described, it does make other pieces of anatomy in the same area appear bigger, so not all bad

  40. #40
    dreadnok89 is offline Member
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    If I skip the gym a couple days they get bigger and fuller. I wonder if I cut down on the nightly exercise and give them a break, if they would get bigger, worth a shot

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