Updated bloods. 22 year old, no libido, weak erections, fatigue, bloating, puffy nipp

[VICREP]

Here are my updated blood tests. I think it's clear what the problem is

E2: 142 pmol (<146) HIGH *note it was around 190 until I took aromasin for a couple weeks
FSH: 5.2 IU/L (1.4-18.0)
LH: 6.2 IU/L (1.5-9.3)
Prolactin 291 mIU/L (45-375) HIGH-NORMAL
SHBG 45 nmol/L (13-71)
Test 1055 ng/dl (230-750) HIGH
Free Test 752 pmol/L (225-725) HIGH
Androstenedione 16.8 nmol/L (2.1-10.8) High
DHEAS 10.9 umol/L (2.2-15.2)
Free T3 4.9 pmol/L (3.5-6.5)
Cortisol 675 nmol/L (119-618) High

All Liver Function test results were perfectly in range.

From this obviously my test/free test is great. I'm guessing my poor libido, weak erections, bloating, puffy nipples and fatigue are due to high E2 and slightly high prolactin.

So I have some Cabergoline on it's way (dostinex so pharma quality) and I just started some Liquidex (arimidex ) but I'm think ing of switching to pharma grade arimidex as well.

I'm thinking Arimidex 0.25mg ED for first week, Caber 0.5mg twice a week, then drop Arimidex to 0.25mg EOD until libido comes back.

Thoughts?

[kelkel]

Doesn't appear to be a sensitive E2 assay? Which would help.
Why are you on TRT at your age?
With caber you'll crush your prolactin with .25 x 2 per week. .5 is overkill.
One week at .25 may be fine. After that I'd go to twice per week, not EOD or you'll end up crushing your E2 quicker than you think. Don't judge your E2 solely by your libido. I'd also check your E2 level in a month.

[FRDave]

Doesn't appear to be a sensitive E2 assay? Which would help.
Why are you on TRT at your age?
With caber you'll crush your prolactin with .25 x 2 per week. .5 is overkill.
One week at .25 may be fine. After that I'd go to twice per week, not EOD or you'll end up crushing your E2 quicker than you think. Don't judge your E2 solely by your libido. I'd also check your E2 level in a month.

Based on his LH and FSH, I don't think he is on TRT, just naturally high test levels I'm assuming... ???

[VICREP]

Yeah sorry I'm not on TRT I just wasn't sure a better place to put my Blood test on this forum.

I'm very happy with my test levels. As they consistently sit above 1000. Free test is great also.

By logic I would have to deduce my problems are merely high E2 and PRL. I wouldn't mind getting my E2 to around 90 pmol/L and prolactin to the bottom end of the range.

With my free test so high would it be safe to assume my DHT is high? I'm still waiting for the DHT tests back

[100%]

Test 1055 ng/dl GOD BLESS YOU! I would want to make sure everything is good with your pituitary. It works both ways meaning a abnormality can make you produce more testosterone prolactin or less?

[VICREP]

I have had x-rays/scan and it all cleared.

I think my E2 and Prolactin were thrown out of whack by my epistane cycle and melanotan 2 use. Hopefully once I get them both stabilized again they will remain lower. Also I'm assuming if my E2 goes back down my Test will go back up. I have had test measured above 1200 ng/dl naturally.

[100%]

I have had x-rays/scan and it all cleared.

I think my E2 and Prolactin were thrown out of whack by my epistane cycle and melanotan 2 use. Hopefully once I get them both stabilized again they will remain lower. Also I'm assuming if my E2 goes back down my Test will go back up. I have had test measured above 1200 ng/dl naturally.

Be careful with stuff never know what your actually getting your naturally gifted hormone wise. Dont want to end up on trt for the rest of your life.

Epistane & P-Plex Analysis

Dietary supplements can be contaminated with stimulants or anabolic steroids that are not declared on their labels. Health concerns over the effects of these supplements continue to surface. In sports doping testing, gas chromatography/mass spectrometry (GC/MS) and liquid chromatography/mass spectrometry (LC/MS) have become powerful tools to identify steroids in dietary supplements.

Several research groups have identified steroids in dietary supplements, such as androst-4-ene-3,6,17- trione (6-OXO), 17α-methyl-5α-androst-2-en-17β-ol (desoxymethyltestosterone, Madol), 1-androgens (1-testosterone , 1-androstenediol etc.), 6α-methylandrostenedione or androsta-1,4,6-triene-3,17-dione. In 2009, 17β-hydroxyandrostano[3,2-c]isoxazole and 17β-hydroxyandrostano[2,3-d]isoxazole were identified in a supplement labelled with the wrong steric composition. These non-licensed and undeveloped toxic steroids tend to be marketed on the Internet. Diel et al. reported that desoxymethyltestosterone is a powerful anabolic steroid with serious toxic side effects.

The aim of this study was to investigate whether the content of two typical dietary supplements, EPISTANE and P-PLEX was correct. The steroids were characterized by GC/MS, LC/MS and NMR. Although the labelling of EPISTANE indicates that it contains 17alpha-methyl-2alpha, 3alpha-epithio-5alpha-androstane-17beta-ol only, 17alpha-methyl-2beta,3beta-epithio-5alpha-androstane-17beta-ol and desoxymethyltestosterone were identified in the supplement. The results showed that P-PLEX contained desoxymethyltestosterone and its isomer 17alpha-methyl-5alpha-androst-3-en-17beta-ol.


Okano M, Sato M, Ikekita A, Kageyama S. Analysis of non-ketoic steroids 17alpha-methylepithiostanol and desoxymethyl- testosterone in dietary supplements. Drug Test Anal 2009;1(11-12):518-25. Analysis of non-ketoic steroids 17alpha-methylepit... [Drug Test Anal. 2009] - PubMed result

Dietary supplements containing 17alpha-methyl-2,3-epithio-5alpha-androstane-17beta-ol (17alpha-methylepithiostanol), which is a 17-methylated analogue of epithiostanol or a prodrug of desoxymethyltestosterone (17alpha-methyl-5alpha-androst-2-en-17beta-ol), have recently appeared on the Internet. 17alpha-Methylepithiostanol and desoxymethyltestosterone are classified as prohibited substances on the World Anti-Doping Agency (WADA) list. Two preparations, EPISTANE and P-PLEX, were obtained from the Internet so that their contents could be investigated. This study involved gas chromatography/mass spectrometry (GC/MS) analysis after trimethylsilyl (TMS) derivatization, liquid chromatography/mass spectrometry (LC/MS) in atmospheric pressure photoionization (APPI) mode and nuclear magnetic resonance (NMR) spectroscopy. Analysis using LC/MS in APPI mode would be a useful tool for detecting heat-labile and non-polar steroids. Although the labelling of EPISTANE indicates that it contains 17alpha-methyl-2alpha, 3alpha-epithio-5alpha-androstane-17beta-ol only, 17alpha-methyl-2beta,3beta-epithio-5alpha-androstane-17beta-ol and desoxymethyltestosterone were identified in the supplement. The results showed that P-PLEX contained desoxymethyltestosterone and its isomer 17alpha-methyl-5alpha-androst-3-en-17beta-ol. Urine samples can be screened after EPISTANE or P-PLEX administration using the normal screening procedure for anabolic steroids with GC/MS.
Attached Files

[kelkel]

Based on his LH and FSH, I don't think he is on TRT, just naturally high test levels I'm assuming... ???

Yep. Read right over that! I ASS-umed!

[kelkel]

Yeah sorry I'm not on TRT I just wasn't sure a better place to put my Blood test on this forum.

I'm very happy with my test levels. As they consistently sit above 1000. Free test is great also.

By logic I would have to deduce my problems are merely high E2 and PRL. I wouldn't mind getting my E2 to around 90 pmol/L and prolactin to the bottom end of the range.

With my free test so high would it be safe to assume my DHT is high? I'm still waiting for the DHT tests back

It's probably up there. Test converts to dht everywhere in the body except skeletal muscle. Don't worry about your DHT unless it low. It makes you a man. You don't want it in the stratosphere but high is fine. It's how you feel.

Test 1055 ng/dl GOD BLESS YOU! I would want to make sure everything is good with your pituitary. It works both ways meaning a abnormality can make you produce more testosterone prolactin or less?

Seriously jealous. And I hate my pituitary.....rotten little fvker.

[VICREP]

It's probably up there. Test converts to dht everywhere in the body except skeletal muscle. Don't worry about your DHT unless it low. It makes you a man. You don't want it in the stratosphere but high is fine. It's how you feel.

I was only wondering what DHT was like since I have heard it has some bearing on libido. I doubt it's related to my libido problems, obviously I need my E2 and PRL down.

Seriously jealous. And I hate my pituitary.....rotten little fvker.

If only I wasn't feeling so sh*t I would be able to hit the gym hard and take advantage of my >1000 test.

[powerlifterty16]

If only I wasn't feeling so sh*t I would be able to hit the gym hard and take advantage of my >1000 test.

you have some awesome natty t levels...but unfortunately your estrogen is terrible....it's hard to win eh?

im the opposite my tt is between 250-340 and estrogen is 9-14 at 23 lol