Trt effects on thyroid?

**simm** · 06-26-2019, 07:39 AM

How much on average would 60mg X 2 week. Effect the thyroid levels?
My TSH has gone up since July last year and cholesterol has too by 0.6.
Strength is good but so tired afterwards.
Endurance is good too.
What are your thoughts?
I'm not cycling. Been on personal trt for 16 weeks.

**Youthful55guy** · 06-26-2019, 08:18 AM

Originally Posted by simm

How much on average would 60mg X 2 week. Effect the thyroid levels?
My TSH has gone up since July last year and cholesterol has too by 0.6.
Strength is good but so tired afterwards.
Endurance is good too.
What are your thoughts?
I'm not cycling. Been on personal trt for 16 weeks.

I don't know of any effect of T on thyroid hormones of on TSH secretion, but I do know that thyroid hormones can definitely have an influence on T levels. Free T to be specific. Thyroid supplementation in euthyroid individuals can profoundly increase SHBG levels. High SHBG levels with decrease Free T and increase Total T. While an increase in Total T may seem good, it is not because most of it is bound and cannot cross the blood-brain barrier where we need it to feel normal.

**simm** · 06-26-2019, 08:29 AM

Thanks for that reply bro. I have more of an understanding now!

**Windex** · 06-26-2019, 01:03 PM

TRT should not impact the thyroid.

Easiest way to improve thyroid is improve sleep and more iodine.

**simm** · 06-27-2019, 05:04 AM

My Dr just called me and said my TSH is high so need bloods in 2 months again before he increases my T4 dosage. Just worried that the trt level testosterone cypionate I'm taking may have effected my TSH

**Windex** · 06-27-2019, 07:33 AM

Thyroid is separate from Test.

Your TRT is not effecting your TSH. Taking T4 is going to increase TSH.

**simm** · 06-27-2019, 08:48 AM

Windex. You just put my mind at rest as was thinking about stopping the trt just to get my TSH levels normal. Knowing it won't be affecting it is a big relief! Thanks bro

**mexecutioner** · 06-27-2019, 11:41 AM

Originally Posted by Windex

Thyroid is separate from Test.

Your TRT is not effecting your TSH. Taking T4 is going to increase TSH.

This is false. Taking T4 will LOWER your TSH.

**GearHeaded** · 06-27-2019, 12:02 PM

Originally Posted by mexecutioner

This is false. Taking T4 will LOWER your TSH.

correct .

TSH, when elevated at high levels tells us that the thyroid gland is not producing enough T4 and the pituitary keeps cranking out more and more TSH to try and get more T4 produced.. if you take exogenous T4 and get your levels in or above range, then your TSH will go down.

windex probably had this backwards , as an increase in TSH should result in an increase in T4 , but not vice versa.

there are 3 components to thyroid hormones.
the pituitary that produces TSH.. then TSH is in the blood stream and available to tell the thyroid gland to produce T4.. then the thyroid produces T4 and thats now available to pass through the liver so the liver can convert that into T3 (which is then active thyroid).
when diagnosing a thyroid problem you need to look at the pituitary, the thyroid gland, and the liver, to determine where in the chain your thyroid issues are stemming from

**GearHeaded** · 06-27-2019, 12:05 PM

keep in mind that though exogenous Testosterone at TRT dose should not be effecting your TSH and T4 , that other drugs we use often times do , for example Tren and HGH

**simm** · 06-27-2019, 02:01 PM

You guys are life savers. Knowing that the test dosage'realistically' shouldn't be affecting my TSH is a big relief. I do have a 3mm pituitary adenoma diagnosis around 10-11yrs ago but I remember the professor saying it was on my hypothalamus. It was non functioning thought. I then 4 weeks after diagnosis received a call from another endocrinologist saying I was sub clinical hypothyroid and needing levothyroxine.