How much is to much HGH?

[Bigdaddy72]

I have takin HGH in the past but I took a some what small does. I have read some sites that people take up to 6-8 iu's a day, everyday for up to six months. My question is how much is to much hgh? What kind of long term affects our we looking at if we take 8 iu's day?

[ascendant]

the biggest concern is the potential to enlarge your heart, which can lead to serious complications down the road. taking 6-8iu's/day for 6 months is ridiculous IMO unless you're planning on making a profession out of competitive bodybuilding and don't mind shaving a good handful (if not more) years off your life.

from my research, the best bet seems to be a continuous intake of 2iu/day year-round for general health benefits, increased collagen synthesis, and so on, and only increasing it during cycles. in small amounts such as 2iu/day, this stuff can be very beneficial for you and can actually prolong your life. however, abuse it and it can cut your life short real quick.

[Ejuicer]

I've been on 6iu's for quite some time and just bumped it to 8iu's a few months ago. I run long duration cycles and that includes the way I run gh as well. I do use 5on/2off however.

[jdavis2007]

I would agree that you should drop down to about 10 iu/wk when you are "off". While "ON" I don't see more than 20 iu/wk being necessary unless you are trying to heal a chronic injury or are a powerlifter/bodybuilder/strongman. Other than that...that's what I would do/am doing.

[graeme87]

I have went up to 20 iu ED and don’t have any apparent side effect i.e. growth hormone gut, bone deformities etc but who knows what effects it could have on my health in the long run. Increase the dose in accordance with your progress.

[Xtralarg]

I have went up to 20 iu ED and don’t have any apparent side effect i.e. growth hormone gut, bone deformities etc but who knows what effects it could have on my health in the long run. Increase the dose in accordance with your progress.

I would be very suspicious of your gear, are you not even experiencing CT?

[IBdmfkr]

I took between 6-10iu for 9months straight and didn't experience any negative sides other than the cost was getting rediculous.
Main thing I noticed was recovery time was increased and I was able to consume more calories and stay leaner, when I came off I didn't change my diet and I actually started putting on a slight bit of bodyfat so I was forced to drop my calories back. Pretty strange.

[BG]

I would be very suspicious of your gear, are you not even experiencing CT?

I totally agree, with I** also.

[graeme87]

CT? I’m not familiar with that term maybe some one can clear that up for me.
Apart from my hands feeling a little numb from time to time I’m fine.

Ps. sorry I didn’t reply sooner I have been over seas and didn’t have net access.

[simm]

CT means Carpal tunnel syndrome..Slight swelling of the wrists causing entrapment of tendon and nerves..Causing the above (you mentioned) :-)

[Halfcenturian]

I took between 6-10iu for 9months straight and didn't experience any negative sides other than the cost was getting rediculous.
Main thing I noticed was recovery time was increased and I was able to consume more calories and stay leaner, when I came off I didn't change my diet and I actually started putting on a slight bit of bodyfat so I was forced to drop my calories back. Pretty strange.

After 9 months would you say you were pleased. Not pleased. Will you repeat HGH therapy? Or is it over-hyped?

[IBdmfkr]

It's a whole different story at my age and yours HalfCent. Also it differs from individual to individual..
For the average person just looking to improve their body I think the price isn't justified.. for someone who is nationally or professionally competing I could see it being worth it.

I'll wait until I'm in my early to mid 30's to use it again but it'll be at a lower dose just to improve health 4-6iu/day.

[vermin]

the biggest concern is the potential to enlarge your heart, which can lead to serious complications down the road. taking 6-8iu's/day for 6 months is ridiculous IMO unless you're planning on making a profession out of competitive bodybuilding and don't mind shaving a good handful (if not more) years off your life.

from my research, the best bet seems to be a continuous intake of 2iu/day year-round for general health benefits, increased collagen synthesis, and so on, and only increasing it during cycles. in small amounts such as 2iu/day, this stuff can be very beneficial for you and can actually prolong your life. however, abuse it and it can cut your life short real quick.

What research is this? LOL - not real research, anyway, since the lowest dose I have seen reported in the literature would be about 21IU/week for a 220 pound man - for 18 months. This was just for basic anti-aging, of course, and there were no mention of, well, ANY of the effects you mention.

That's Rudman et. al. 1991, which you will have read, of course, if you have done all of this "research" since it is the document fouding HGH as an anti-aging tool and the paper from which all of this flows, so it is the first paper one must read - if one does "research" into HGH....

[Halfcenturian]

It's a whole different story at my age and yours HalfCent. Also it differs from individual to individual..
For the average person just looking to improve their body I think the price isn't justified.. for someone who is nationally or professionally competing I could see it being worth it.

I'll wait until I'm in my early to mid 30's to use it again but it'll be at a lower dose just to improve health 4-6iu/day.

I didn't realize you were still a youngster! 26. I can see your point, bro.
YOU DON'T NEED IT.
Every guy I've asked over the age of 45-50, says it's a fantastic complement to TRT. If not Magic. I gotta try it.

[jbarkley]

I didn't realize you were still a youngster! 26. I can see your point, bro.
YOU DON'T NEED IT.
Every guy I've asked over the age of 45-50, says it's a fantastic complement to TRT. If not Magic. I gotta try it.

Halfcenturian, I have been on it for 14 months with TRT and it's made an incredible difference in many aspects of my overall being. I started it 6 months after completing Chemotherapy for Lymphoma and I was pretty beat down....within 4 months of starting hgh I felt like a new man. You really need to give it a try! Good luck...

Livestrong

[ascendant]

What research is this? LOL - not real research, anyway, since the lowest dose I have seen reported in the literature would be about 21IU/week for a 220 pound man - for 18 months. This was just for basic anti-aging, of course, and there were no mention of, well, ANY of the effects you mention.

That's Rudman et. al. 1991, which you will have read, of course, if you have done all of this "research" since it is the document fouding HGH as an anti-aging tool and the paper from which all of this flows, so it is the first paper one must read - if one does "research" into HGH....

k son, for starters, get an avy up of yourself before you start trying to talk trash. secondly, for anti-aging purposes, 2-3iu/day is sufficient. here's the link: My Guide to HGH for anyone interested. so you want to argue, go argue with redbaron, a vet who knows well more than you i'm sure.

as far as whatever it is you claim you read and it not mentioning the side effects i explained, here is some proof from pubmed and a few other good resources:
http://www.ncbi.nlm.nih.gov/entrez/q...=pubmed_docsum
http://entertainment.howstuffworks.c...drug-test2.htm
http://www.antiaginginfo.net/hgh-side-effects.htm

as far as rudman, to be quite honest, never heard of him and don't really care to read what he has to say considering you have his studies dated at 1991 which is a bit outdated. now, i'm sure he probably has kept up with studies on it to date, but just because he was the founder does not by any means mean he's the most knowledgeable.

now, i never said people don't take more HGH. i'm just suggesting the safest doseage for him. during cycles, sure, bump it up for a while. however, the more you increase your dose past 3-4iu/day, the more you risk serious side-effects. maybe some people can get away with 10+iu/day for years and be fine. however, it's similar to smoking. some people can smoke for years and be fine, but others will cut their lives short because of it. personally i'd rather keep my dose of HGH at a level that i know will be beneficial for me and not harmful and i wouldn't personally suggest someone do otherwise.

[Ufa]

Most of the old studies were done on dwarfs and mice. Fifteen
year old studies. Thats almost back when they were using GH
from humans - The results have not been talked about so I wil
remind you of -mad cow- only in humans. Taken from human
cadavers.

[vermin]

k son, for starters, get an avy up of yourself before you start trying to talk trash. secondly, for anti-aging purposes, 2-3iu/day is sufficient. here's the link: My Guide to HGH for anyone interested. so you want to argue, go argue with redbaron, a vet who knows well more than you i'm sure.

as far as whatever it is you claim you read and it not mentioning the side effects i explained, here is some proof from pubmed and a few other good resources:
http://www.ncbi.nlm.nih.gov/entrez/q...=pubmed_docsum
http://entertainment.howstuffworks.c...drug-test2.htm
http://www.antiaginginfo.net/hgh-side-effects.htm

as far as rudman, to be quite honest, never heard of him and don't really care to read what he has to say considering you have his studies dated at 1991 which is a bit outdated. now, i'm sure he probably has kept up with studies on it to date, but just because he was the founder does not by any means mean he's the most knowledgeable.

now, i never said people don't take more HGH. i'm just suggesting the safest doseage for him. during cycles, sure, bump it up for a while. however, the more you increase your dose past 3-4iu/day, the more you risk serious side-effects. maybe some people can get away with 10+iu/day for years and be fine. however, it's similar to smoking. some people can smoke for years and be fine, but others will cut their lives short because of it. personally i'd rather keep my dose of HGH at a level that i know will be beneficial for me and not harmful and i wouldn't personally suggest someone do otherwise.

That's just funny. Sorry - but I just read the Barton et. al abstract you referenced and, among other things, it concludes the exact opposite of what you evidently think it says. And of course, what I cited was anti-aging research, what you cited was a children's study. The rest you cited was pap.

Here are some hints:

After one year r-hGH treatment LVMI was 71 g/m2 (observation group), 73 g/m2 (20 IU/m2/week group) and 74 g/m2 (40 IU/m2/week group) (P = 0.77). LVMI increased significantly from baseline to 76 g/m2 after 2 years therapy with 40 IU/m2/week r-hGH (P = 0.04) but nevertheless remained within the normal range.

High dose (40 IU/m2/week) r-hGH treatment of children with idiopathic short stature resulted in a greater short-term acceleration in growth rate than 'standard' dose therapy without an excessive advance in skeletal maturity and probably represents the optimal growth promoting dose.

Get it - no harm to the heart and they suggest using the high dose method. While I thank you for pointing me to a paper with which I was not familiar (I do tend to ignore much of the children stuff) I am not surprised that they follow the overwhelming trend to high dose HGH in the literature.

If you have not read Rudman et. al. 1990 then you do not understand how to do "library" research. But that's OK, you evidently don't understand how to interpret what you read anyway. I suppose the nice thing is, folks can read what we both have to say and decide for themselves....

[ascendant]

k, Vermin, there was apparently a lot of info that i provided that you had overlooked. let me just keep it simple here...

do you or do you not believe that HGH causes acr*****ly? if you deny that, you deny a side-effect that many HGH long-term, high-dose user gets down the road. now, acr*****ly does include enlarging of the heart and kidneys in particular. so, by saying it doesn't enlarge the heart, you're trying to claim that it doesn't cause acr*****ly, which is ridiculous.

additionally, how can you really believe there's no sides to this in excessive doses??? take one look at the pro's and you'll see one that's across the board. i'm talking the distended belly from, i believe, enlarged intestines (i may be wrong on this wrong but i'm pretty sure that's the cause).

i don't care what kind of material you've read that's claiming this stuff is safe at any dose. real life tells a much different story.

[vermin]

do you or do you not believe that HGH causes acr*****ly? if you deny that, you deny a side-effect that many HGH long-term, high-dose user gets down the road. now, acr*****ly does include enlarging of the heart and kidneys in particular. so, by saying it doesn't enlarge the heart, you're trying to claim that it doesn't cause acr*****ly, which is ridiculous.

Of course it does, but not in the doses and time frames I have suggested. You said that acr*****ly and heart enlargement would occur at 6-8IUs a day for 6 months. That's a big negatory there, at least in terms of meaningful, measurable amounts. That 6-8IU dose has been shown to be safe with no appreciable acr*****ly or most other sides for 18+ months in many many studies now. Possible hastening of Type II diabtese for those already predisposed, yes, but that's about it and there's evidence that can happen at any dose - including your 2IU/day.

additionally, how can you really believe there's no sides to this in excessive doses??? take one look at the pro's and you'll see one that's across the board. i'm talking the distended belly from, i believe, enlarged intestines (i may be wrong on this wrong but i'm pretty sure that's the cause).

i don't care what kind of material you've read that's claiming this stuff is safe at any dose. real life tells a much different story.

Never said safe at any dose, just that 6IU/day on 5/2 for a 220 pound man is safe, and that 21IU/week is more appropriate for anti-aging results. I also indicated that the literature is pointing to more and more shorter-term higher dose uses of HGH, which it is. In point of fact, if you wish to use HGH for muscular development the best evidence right now is that that hypothetical 220 pound male is better off taking 18IU ED for 4 weeks than using those same 500IUs over 6 months. So far, this is primarily in the literature as we have few anecdotal reports from BBs on this - but I think it is coming.

I realize that if you change your argument, and attempt to reframe mine at every post you can appear to be making sense - if everyone forgets what's been said before. I, for one at least, have not.

[ascendant]

Of course it does, but not in the doses and time frames I have suggested. You said that acr*****ly and heart enlargement would occur at 6-8IUs a day for 6 months. That's a big negatory there, at least in terms of meaningful, measurable amounts. That 6-8IU dose has been shown to be safe with no appreciable acr*****ly or most other sides for 18+ months in many many studies now. Possible hastening of Type II diabtese for those already predisposed, yes, but that's about it and there's evidence that can happen at any dose - including your 2IU/day.

Never said safe at any dose, just that 6IU/day on 5/2 for a 220 pound man is safe, and that 21IU/week is more appropriate for anti-aging results. I also indicated that the literature is pointing to more and more shorter-term higher dose uses of HGH, which it is. In point of fact, if you wish to use HGH for muscular development the best evidence right now is that that hypothetical 220 pound male is better off taking 18IU ED for 4 weeks than using those same 500IUs over 6 months. So far, this is primarily in the literature as we have few anecdotal reports from BBs on this - but I think it is coming.

I realize that if you change your argument, and attempt to reframe mine at every post you can appear to be making sense - if everyone forgets what's been said before. I, for one at least, have not.

well, i also never said that 6-8iu/day would definitely cause acr*****ly. i was merely pointing out one potential side-effect. however, just as you stated in your above post, there are other sides, such as the distended belly, which i did see someone get from a comparable dose (at least from what he claimed).

as far as it not being that risky, i'm not saying it is. however, all i was trying to tell him is that if you want to make sure there's no risk, 2-3iu/day is perfectly safe for virtually everyone. as you go above 4iu/day, then you gradually increase your risk for sides. for example, i know one of my friends who can't do anymore than 3.5iu/day. if he does 4iu/day, he gets carpal tunnel. now to me, that's certainly a side-effect, and it's only at 4iu/day.

as far as what you said about arguing, i'm not. i may be a wise-ass at times, but it's all in good humor with me. i don't get p*ssed for someone else having a different opinion on here. it's all good on my end man, as i'd like to think you're just trying to help, as am i.

to be honest, i've only studied extensively into AAS and the things that go along with it (PCT, etc.) and have just recently begun researching HGH. i'm merely providing the best info i can from the research i've gained so far. you probably are well more knowledgeable in this field than me, but all i'm saying is that you can't say there's absolutely no risk of doing 6-8iu/day for a prolonged period of time.

[gixxerboy1]

the biggest concern is the potential to enlarge your heart, which can lead to serious complications down the road. taking 6-8iu's/day for 6 months is ridiculous IMO unless you're planning on making a profession out of competitive bodybuilding and don't mind shaving a good handful (if not more) years off your life.

from my research, the best bet seems to be a continuous intake of 2iu/day year-round for general health benefits, increased collagen synthesis, and so on, and only increasing it during cycles. in small amounts such as 2iu/day, this stuff can be very beneficial for you and can actually prolong your life. however, abuse it and it can cut your life short real quick.

I ran 4-6iu's ed my last time. The other couple times i did it i did 2iu's ed. I would never run 2iu's again. To me it was a waste of money there wasn't enough benefits