Results 1 to 13 of 13
Like Tree4Likes
  • 2 Post By kelkel
  • 1 Post By JohnnyBreeze
  • 1 Post By kelkel

Thread: Drop in HDL due to arimidex, Any alternative?

  1. #1
    belva's Avatar
    belva is offline Member
    Join Date
    Jan 2013
    Location
    Hong Kong
    Posts
    562

    Drop in HDL due to arimidex, Any alternative?

    5 years in to my competitive bodybuilding Journey and my good cholesterol HDL has never been higher than 36mg/dl. Normally fluctuating between 13 mg/dl to 26mg/dl.

    Based on my bloodwork, average every 4 months, I know its the arimidex that drop it down, I tried novadex but still the results stays around 25 mg/dl. I tried not to use ancillary (the cholesterol problem is solved, HDL 44-49mg/dl )but the 17-estradiol rise so much that it screw with brain and I cant cope with that.

    My total cholesterol is not hight around 160mg/dl normally, LDL 130mg/dl triglycerides 60 to 80 mg/dl

    so normally my T col/HDL is around 7

    I have always used Extra Virgin olive oil (I'm italian, I make it), Avocado, nuts (Fat consumption around 100g a day) with 5g of EPA/DHA a day.

    DOES anyone knows any way out there to use any ancilliary that can allow my good colesterol HDL to stay higher?

    Thank you for taking the time to read it and advise.

  2. #2
    belva's Avatar
    belva is offline Member
    Join Date
    Jan 2013
    Location
    Hong Kong
    Posts
    562
    I forgot to mention the dose of arimidex I am taking variate from is 0,5 mg E3D in off season on a basic test cyp 400*w to 1mg EOD on a pre contest cycle of test/tren /mas and Winstrol .

    Still on 0,5 mg E3D or even E4D my good HDL still down betwwen 13mg/dl to 25mg/dl.

  3. #3
    beanpo1e is offline Junior Member
    Join Date
    Jul 2020
    Posts
    85
    High dose Niacin can substantially raise HDL cholesterol. The protocol I saw said take 1.5g three times per day. It causes you to flush red and heat up when you first take it, but over time you tolerate it better.

  4. #4
    Test Monsterone's Avatar
    Test Monsterone is online now Senior Member
    Join Date
    Jun 2018
    Posts
    1,400
    I have also heard something about the niacin, but I heard that it takes months to see results.

    I would suggest some oats with each meal, as they tend to absorb fats in the digestive system.

    Also, cardio seems to help HDL a bit, according to some doctors.

  5. #5
    kelkel's Avatar
    kelkel is offline HRT Specialist ~ AR-Platinum Elite-Hall of Famer ~ No Source Checks
    Join Date
    Sep 2010
    Location
    East Coast Dungeon
    Posts
    28,962
    Certain Niacin's like the guys mentioned above. I use either Slo-Niacin or Endur-Acin. Lately I prefer the latter which I'll take at least twice daily with lunch and at bedtime. It will help.
    956Vette and almostgone like this.
    -*- NO SOURCE CHECKS -*-

  6. #6
    JohnnyBreeze's Avatar
    JohnnyBreeze is offline Junior Member
    Join Date
    Jun 2019
    Location
    Louisiana
    Posts
    119
    Quote Originally Posted by kelkel View Post
    Certain Niacin's like the guys mentioned above. I use either Slo-Niacin or Endur-Acin. Lately I prefer the latter which I'll take at least twice daily with lunch and at bedtime. It will help.
    I donít want to hijack this thread, but the study Iíve read (and Iíve only read one) specifically says not to use ďlong acting forms of niacinĒ. Since I know there are always conflicting studies, and I have been wanting to start Niacin for my LDL (low normal) and triglycerides, I have three questions.

    1. How much improvement have you seen using the long acting forms that you take (in LDL, HDL, or Triglycerides)?

    2. What is the total dose (mg) for the day that you take?

    3. Have you run into any side effects other than flushing? Iíve been reading about some that are pretty serious, such as worsening blood sugar or insulin resistance to the point of type 2 diabetes.

    Thanks.
    956Vette likes this.

  7. #7
    AR's King Silabolin's Avatar
    AR's King Silabolin is online now Castle Power
    Join Date
    May 2015
    Location
    Norway
    Posts
    6,387
    Quote Originally Posted by belva View Post
    5 years in to my competitive bodybuilding Journey and my good cholesterol HDL has never been higher than 36mg/dl. Normally fluctuating between 13 mg/dl to 26mg/dl.

    Based on my bloodwork, average every 4 months, I know its the arimidex that drop it down, I tried novadex but still the results stays around 25 mg/dl. I tried not to use ancillary (the cholesterol problem is solved, HDL 44-49mg/dl )but the 17-estradiol rise so much that it screw with brain and I cant cope with that.

    My total cholesterol is not hight around 160mg/dl normally, LDL 130mg/dl triglycerides 60 to 80 mg/dl

    so normally my T col/HDL is around 7

    I have always used Extra Virgin olive oil (I'm italian, I make it), Avocado, nuts (Fat consumption around 100g a day) with 5g of EPA/DHA a day.

    DOES anyone knows any way out there to use any ancilliary that can allow my good colesterol HDL to stay higher?

    Thank you for taking the time to read it and advise.
    There is no such thing as good and bad cholestrol.

    Sent fra min BLA-L29 via Tapatalk


    Last edited by AR's King Silabolin; 10-07-2020 at 08:44 PM.

  8. #8
    Mr. Small's Avatar
    Mr. Small is offline Member
    Join Date
    Sep 2011
    Location
    Ireland
    Posts
    625
    Quote Originally Posted by AR's King Silabolin View Post
    There is no such thing as good and bad cholestrol.

    Sent fra min BLA-L29 via Tapatalk


    Huh? Bad cholesterol clogs your veins

  9. #9
    DustMan is online now Junior Member
    Join Date
    Dec 2013
    Posts
    122
    LDL (specifically VLDL or any form less than 70nm) is the primary causal factor in the development of CVD. HDL doesn't pass through the endothelial barrier and participate in CVD, it helps to transport cholesterol back to the liver and lowers total LDL levels.

    Too much LDL, and more specifically VLDL, LDL fragments, and small electronegative LDL are the driving forces of CVD. If you don't control your LDL you're rolling the dice on having godlike genetics, because if you don't.... you're gonna end up with CVD.

    Here's some really long but interesting reading on LDL and CVD: https://academic.oup.com/eurheartj/a...4/2313/5735221

    Belva, have you looked into PCSK9 inhibitors or Bile Acid Resins? PCSK9's are the new statin.... so far they look to have way less side effects than statins and are highly tolerable. They might have long term negative effects that we haven't seen yet, but so far so good, really expensive right now though and not covered by many medical plans.

    Bile acid resins on the other hand have 0 systematic side effects, ask your Doctor about them, I'm trying to find where I can buy some here in Germany at the moment without a prescription. They lower LDL and raise HDL, only problem is you can't take them around food / other supplements because they will bind to them and waste them.

    Edited in: LDL and HDL are both really important in determining your risk of further CVD development, but there are lots of things you can do which can slow and even reverse CVD, I'll list a couple of them here for you.

    Omega3: Supplementation reduces sterile inflammation of the arterial wall preventing further development of CVD. Supplementation leads to reduced triglyceride and c reactive protein levels. Very important.

    CoQ10: Promotes NO dependent vasodialation and protects LDL from oxidization(LDL is the primary carrier of Ubiquinol, the good version of CoQ10). Oxidized LDL merges with the arterial wall and begins the process of necrosis, eventually leading to a thrombus, and becoming a clot.

    Vitamin K2: Reduces arterial calcification and increases vascular flexibility, reducing rate of cardio vascular incidence.
    Last edited by DustMan; 10-16-2020 at 03:45 AM. Reason: More info:

  10. #10
    kelkel's Avatar
    kelkel is offline HRT Specialist ~ AR-Platinum Elite-Hall of Famer ~ No Source Checks
    Join Date
    Sep 2010
    Location
    East Coast Dungeon
    Posts
    28,962
    Quote Originally Posted by JohnnyBreeze View Post
    I don’t want to hijack this thread, but the study I’ve read (and I’ve only read one) specifically says not to use “long acting forms of niacin”. Since I know there are always conflicting studies, and I have been wanting to start Niacin for my LDL (low normal) and triglycerides, I have three questions.

    1. How much improvement have you seen using the long acting forms that you take (in LDL, HDL, or Triglycerides)?

    2. What is the total dose (mg) for the day that you take?

    3. Have you run into any side effects other than flushing? I’ve been reading about some that are pretty serious, such as worsening blood sugar or insulin resistance to the point of type 2 diabetes.

    Thanks.

    https://forums.steroid.com/hormone-r...xperiment.html
    DustMan likes this.
    -*- NO SOURCE CHECKS -*-

  11. #11
    AR's King Silabolin's Avatar
    AR's King Silabolin is online now Castle Power
    Join Date
    May 2015
    Location
    Norway
    Posts
    6,387
    Quote Originally Posted by Mr. Small View Post
    Huh? Bad cholesterol clogs your veins
    Nope. We all have lots of ldl. If it was bad, there would be clogs all over. But it isnt so.
    Too much water, doesnt sink your boat.

    Sent fra min BLA-L29 via Tapatalk

  12. #12
    AR's King Silabolin's Avatar
    AR's King Silabolin is online now Castle Power
    Join Date
    May 2015
    Location
    Norway
    Posts
    6,387
    Quote Originally Posted by DustMan View Post
    LDL (specifically VLDL or any form less than 70nm) is the primary causal factor in the development of CVD. HDL doesn't pass through the endothelial barrier and participate in CVD, it helps to transport cholesterol back to the liver and lowers total LDL levels.

    Too much LDL, and more specifically VLDL, LDL fragments, and small electronegative LDL are the driving forces of CVD. If you don't control your LDL you're rolling the dice on having godlike genetics, because if you don't.... you're gonna end up with CVD.

    Here's some really long but interesting reading on LDL and CVD: https://academic.oup.com/eurheartj/a...4/2313/5735221

    Belva, have you looked into PCSK9 inhibitors or Bile Acid Resins? PCSK9's are the new statin.... so far they look to have way less side effects than statins and are highly tolerable. They might have long term negative effects that we haven't seen yet, but so far so good, really expensive right now though and not covered by many medical plans.

    Bile acid resins on the other hand have 0 systematic side effects, ask your Doctor about them, I'm trying to find where I can buy some here in Germany at the moment without a prescription. They lower LDL and raise HDL, only problem is you can't take them around food / other supplements because they will bind to them and waste them.

    Edited in: LDL and HDL are both really important in determining your risk of further CVD development, but there are lots of things you can do which can slow and even reverse CVD, I'll list a couple of them here for you.

    Omega3: Supplementation reduces sterile inflammation of the arterial wall preventing further development of CVD. Supplementation leads to reduced triglyceride and c reactive protein levels. Very important.

    CoQ10: Promotes NO dependent vasodialation and protects LDL from oxidization(LDL is the primary carrier of Ubiquinol, the good version of CoQ10). Oxidized LDL merges with the arterial wall and begins the process of necrosis, eventually leading to a thrombus, and becoming a clot.

    Vitamin K2: Reduces arterial calcification and increases vascular flexibility, reducing rate of cardio vascular incidence.
    Totally wrong. Best jap scientists, say those with high ldl, live longer.
    So do the best denish experts. And others who are not from the same mainstream old school.
    Yeah many who die, have high ldl. But the things which caused high ldl also killed them.
    High BP f. i. When high BP causes damage to the veins, cracks are filled with cholesterol and other things making bulps. Thats rigth.
    But cholestrol would also contribute to these bulps, even if the amount of cholestrol was textbook to begin with.

    If your cup has a crack in the bottom . It will fill first, then the cup itself, when u put water in it.
    The crack would fill, no matter how much water u got . 1 dl. 10 dl. Doesnt mean shit.

    Sent fra min BLA-L29 via Tapatalk

  13. #13
    DustMan is online now Junior Member
    Join Date
    Dec 2013
    Posts
    122
    Quote Originally Posted by AR's King Silabolin View Post
    Totally wrong. Best jap scientists, say those with high ldl, live longer.
    So do the best denish experts. And others who are not from the same mainstream old school.
    Yeah many who die, have high ldl. But the things which caused high ldl also killed them.
    High BP f. i. When high BP causes damage to the veins, cracks are filled with cholesterol and other things making bulps. Thats rigth.
    But cholestrol would also contribute to these bulps, even if the amount of cholestrol was textbook to begin with.

    If your cup has a crack in the bottom . It will fill first, then the cup itself, when u put water in it.
    The crack would fill, no matter how much water u got . 1 dl. 10 dl. Doesnt mean shit.

    Sent fra min BLA-L29 via Tapatalk
    Looks like the scientific community disagrees with the claims of the experts who performed the narrative summary you are alluding to:
    https://www.nhs.uk/news/heart-and-lu...heart-disease/

    I read the study before I went looking for how the scientific community feels about it and I was very unimpressed with it, they don't account for any additional variables like medication(statins) or dietary/lifestyle interventions. Here is the original study: https://bmjopen.bmj.com/content/6/6/e010401.full

    High blood pressure is a major concern with CVD, but LDL(specifically smaller LDL) can pass through the endothelial barrier without it being damaged. I'm not going to roll the dice on a blood clot.

Thread Information

Users Browsing this Thread

There are currently 1 users browsing this thread. (0 members and 1 guests)

Tags for this Thread

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •