Page 2 of 2 FirstFirst 12
Results 41 to 59 of 59
Like Tree1Likes

Thread: Insulin Resistance

  1. #41
    Turkish Juicer's Avatar
    Turkish Juicer is offline Knowledgeable Member
    Join Date
    Feb 2011
    Location
    Istanbul
    Posts
    2,984
    Quote Originally Posted by gixxerboy1 View Post
    I agree about the cutting part. but since we were talking about insulin resistance. So as Turkish posted. The 1 large release would be better then a lower prolonged for insulin resistance. I'm curious if there is a study or some science behind it.
    hey gixxer,

    I went back and read all my posts under this thread after reading your post above, and I see that my contribution to this thread has solely revolved around the concept of continuous circulation of insulin in the metabolic system and its downsides concerning cutting purposes, not insulin resistance itself. Title of the thread may be Insulin Resistance but my contribution to the thread has been specifically along the lines of presence of insulin in the system and its disadvantage concerning fat loss from an anatomical perspective.

  2. #42
    gixxerboy1's Avatar
    gixxerboy1 is offline ~VET~ Extraordinaire~
    Join Date
    Sep 2001
    Location
    Texas
    Posts
    32,803
    Quote Originally Posted by Turkish Juicer View Post
    hey gixxer,

    I went back and read all my posts under this thread after reading your post above, and I see that my contribution to this thread has solely revolved around the concept of continuous circulation of insulin in the metabolic system and its downsides concerning cutting purposes, not insulin resistance itself. Title of the thread may be Insulin Resistance but my contribution to the thread has been specifically along the lines of presence of insulin in the system and its disadvantage concerning fat loss from an anatomical perspective.
    ok, thanks for the clarification.
    If people can't tell your on steroids then your doing them wrong

  3. #43
    Bonaparte's Avatar
    Bonaparte is offline AR-Hall of Famer
    Join Date
    Aug 2009
    Posts
    13,471
    What about metformin? That is the first line treatment for type II DM.

    Also, Biotest makes a supp called Receptormax, which is aimed at increasing insulin sensitivity. I would just look into each ingredient separately:

    Acetyl-L-carnitine

    Cinnamomum burmanni (water extract, standardized for type-A polymers, tetramers, and trimers)

    Na (sodium) R-alpha-lipoic acid

    Coenzyme Q10

    4-hydroxyisoleucine
    Last edited by Bonaparte; 06-09-2012 at 05:58 PM.

  4. #44
    SexySweetheart is offline "Decide you want it ƸӜƷ more than your afraid of it"Recognized Member Winner - $100
    Join Date
    Jul 2011
    Posts
    3,373
    Quote Originally Posted by gbrice75 View Post
    For those of you who know me, you know I have struggled to gain lean mass. In fact, i've struggled to gain any muscle at all. My last 'add lean mass' run, while I admittedly didn't stick to my plan 100%, was a total failure IMO as I didn't gain any noticeable muscle but did gain a lot of fat.

    This really made me start questioning things. How could this be possible? I can understand the fat gain if the diet gets sloppy and cardio is neglected (both of which happened on my last run)... but I couldn't understand why i'd gain NO muscle. I met all the following criteria:

    - trained sufficiently and with intensity, i.e. gave my body a reason to grow
    - hit my macros (went over if anything)
    - sufficient protein, carbs and fat - definite caloric surplus (evident in the fat gains)
    - sufficient sleep
    - bloodwork shows 'within normal range' test levels

    I started thinking about insulin resistance. Without going too much into HOW we become insulin resistant (that's another topic that deserves it's own thread), suffice it to say a leading culprit is poor diet (high fat/sugar/processed calorie dense food) and no exercise. Well, that pretty much sums up my life throughout my 20's.

    Insulin resistance is a 'condition' whereby our cells become resistant to insulin. Insulin is a hormone that's responsible for shuttling nutrients into our cells. Basically, we eat - let's say carbs for an easy example - carbs are eventually broken down into their simplest form, glucose. Our blood glucose levels rise. The pancreas is triggered to secrete insulin to 'clean up' the glucose in our bloodstream, shuttling it to be stored into our cells - muscle (as glycogen), liver (as glycogen), and fat (as tryglycerides). You can see how a constant diet high in fat and carbs (not to mention caloric surplus) can keep blood glucose levels high, requiring insulin to continuously be released. Continuous circulating insulin can, over time, cause cells to become insulin resistant.

    This made perfect sense for my case - muscles weren't growing in proportion to my training because they weren't benefitting from insulin in my bloodstream. i.e. glucose uptake in the cells was limited. But why would I so easily store bodyfat then, if cells have become resistant? Isn't it an 'all or none' type of thing? Then I came across this little read, which was like an epiphony for me:

    Once established, insulin resistance would result in increased circulating levels of insulin. Since insulin is the primary hormonal signal for energy storage into fat cells, which tend to retain their sensitivity in the face of hepatic and skeletal muscle resistance, IR stimulates the formation of new fatty tissue and accelerates weight gain - Elvira Isganaitis; Robert H. Lustig (2005). "Fast Food, Central Nervous System Insulin Resistance, and Obesity". Arteriosclerosis, Thrombosis, and Vascular Biology

    This spoke volumes to me. This answers my questions. Now it makes perfect sense as to why i'd add fat but not muscle, even though the environment for muscle growth is present. But finding this was the easy part. 'Fixing' it is a whole different animal. So what can we do to decrease insulin resistance, or better put - increase insulin sensitivity?

    - limit sugar intake. This is a no brainer. Spiking BGL's and the subsequent insulin response is counter productive. So forget your PWO 'fast acting carbs' - they will only hurt you in this case.

    - limit overall carb intake. If you're trying to lower your resistance to insulin, then eating 400g of carbs per day isn't going to help, even if they're the cleanest most complex carbs ever.

    - extend the time between when your workout ends and you have your PWO meal, particularly carbs. Studies have shown an increase in insulin sensitivity when food isn't eaten immediately PWO.

    - Exercise - duh

    - Fasting - I'll be exploring this (again), with the new goal of increasing my sensitivty to insulin. It's logical to think that keeping BGL low and insulin supressed will, over time, increase sensitivity

    - Keep fat intake low - I don't mean 10g a day, just be moderate. Personally, I don't let fat make up more than 15% of my diet.

    - DO supplement with fish oil. Omega-3 fatty acids have been shown to have a positive effect in increasing insulin sensitivity

    I will add more as I think of them/research further. Hopefully this will get a dialogue going which will prompt more questions... and responses. I hope this helps some of you with your own confusion on the topic.

    Thanks for posting this GB!
    i loved all the technical jargon and how you eloquently explain what you understand (not my strength lol) it really made me feel great cuz thatís what I have been thinking all along about myself and how my body works, which resulted in my diverting massively from the meal planning originally suggested by the guruís~ which I, at first felt bad about doing, like I didnít value their time or input (which I totally did value)

    Also I see this in ALOT of the over weight gals on the site (and some guys) as I watch their frustration when they two start plans laid out for them by the board members that mean well, are educated, and are also males that were most likely never very over weight, with the result that alot of the females give up and leave the site

    I wonder if it would be appropriate to ask the powers that be, too make this a sticky in the nutrition forum.
    You know as another option for gals and some guys instead of just the main stream suggestions of 5 meal plans that PWO include brown rice, sweet potatoes, oatmeal, yogurts, fruits etc.

  5. #45
    Ishallnocheatmyself's Avatar
    Ishallnocheatmyself is offline Associate Member
    Join Date
    Aug 2010
    Posts
    266
    where i only have about 15-20% of my pancrease , will your guidelines to increasing sensitivty still apply mate? nice read btw
    Last edited by Ishallnocheatmyself; 06-10-2012 at 10:23 PM. Reason: made a booboo

  6. #46
    gbrice75's Avatar
    gbrice75 is offline AR's Diet Pimp! ~HOF~
    Join Date
    Nov 2009
    Location
    New Jersey
    Posts
    17,457
    Quote Originally Posted by numero_uno View Post
    I want to thank you for posting this. It's something I've been aware of in the past, but I have never done any real research on. However, because my doctor recently recommended I get an insulin resistance test, I am starting to do so now.
    Glad you enjoyed it! I'm likely going to be tested soon as well.

    Quote Originally Posted by gixxerboy1 View Post
    ok say you took 1 large meal. what ever the breakdown is and divided it into to smaller meals. Why would you have more insulin on the 2 meals instead of 1. Yes you would have another "pulse" but your body shouldnt produce a higher total amount of insulin since in theory you are eating exactly the same. it should be 2 smaller pulses instead of one larger one
    I agree that total insulin would be roughly the same amount. The larger meal would provide a larger spike that would last longer. The smaller meals would provide smaller spikes that wouldn't last as long, however for cutting purposes I would prefer one big blast (could also help with growth if timed well) and then a prolonged period of supressed insulin.

    Quote Originally Posted by gixxerboy1 View Post
    I agree about the cutting part. but since we were talking about insulin resistance. So as Turkish posted. The 1 large release would be better then a lower prolonged for insulin resistance. I'm curious if there is a study or some science behind it.
    ^^ check out Leangains. Martin references many studies - I can't recall any specifically regarding insulin resistance, but you may be able to make an informed determination based on related info.

    Quote Originally Posted by Bonaparte View Post
    What about metformin? That is the first line treatment for type II DM.

    Also, Biotest makes a supp called Receptormax, which is aimed at increasing insulin sensitivity. I would just look into each ingredient separately:

    Acetyl-L-carnitine

    Cinnamomum burmanni (water extract, standardized for type-A polymers, tetramers, and trimers)

    Na (sodium) R-alpha-lipoic acid

    Coenzyme Q10

    4-hydroxyisoleucine
    Thx for the info B. I have been thinking about Metformin lately myself, pending an IR test. Maybe i'll look into these 'ingredients'.

    Quote Originally Posted by Sexy4mySweetheart View Post
    Thanks for posting this GB!
    i loved all the technical jargon and how you eloquently explain what you understand (not my strength lol) it really made me feel great cuz that’s what I have been thinking all along about myself and how my body works, which resulted in my diverting massively from the meal planning originally suggested by the guru’s~ which I, at first felt bad about doing, like I didn’t value their time or input (which I totally did value)
    You're welcome, glad you enjoyed it!

    Quote Originally Posted by Sexy4mySweetheart View Post
    Also I see this in ALOT of the over weight gals on the site (and some guys) as I watch their frustration when they two start plans laid out for them by the board members that mean well, are educated, and are also males that were most likely never very over weight, with the result that alot of the females give up and leave the site

    I wonder if it would be appropriate to ask the powers that be, too make this a sticky in the nutrition forum.
    You know as another option for gals and some guys instead of just the main stream suggestions of 5 meal plans that PWO include brown rice, sweet potatoes, oatmeal, yogurts, fruits etc.
    Feel free to PM admin and ask him to make this a sticky! I would, but I am enough of a self-promoting whore as it is, lol!

    Quote Originally Posted by Ishallnocheatmyself View Post
    where i only have about 15-20% of my pancrease , will your guidelines to increasing sensitivty still apply mate? nice read btw
    I'm no doctor and it would be irresponsible for me to advise you on this. Do you produce very low amounts of insulin due to having very little pancreas? i.e. are you borderline Type 1 diabetic?

  7. #47
    oscarjones is offline Banned
    Join Date
    Sep 2009
    Location
    USA
    Posts
    1,242
    Remember guys Adrenals relate to your blood sugar as well. For example, "a chocolate addiction" can be a symptom of adrenal problems. Or, if you ever wake up in the middle of the night at around 3-4 AM it can be be due to low nocturnal cortisol. Basically, cortisol reaches very low levels to the point where it causes hypogly***ia.

    Lets say you eat a sugary carb meal right before bed or very late in the evening, the instant high sugar (in a candy bar, let's assume) triggers a strong insulin response. If your adrenals aren't healthy they will not make enough cortisol, specifically at night, to raise your glucose after that big surge of insulin dropped it. When you have low blood sugar the body produces adrenaline, and it just so happens that around 3-4 AM is the body's normal time to have the naturally lowest glucose levels, partly due to fasting for 5+ hours.

    So basically, to recap, the reason you wake up, hypogly***ia causes production of adrenaline. And cortisol is responsible for helping to keep blood glucose stable via gluconeogenesis, which is the body's way of metabolizing glucose from non-carb sources, such as proteins and lipids.

  8. #48
    SexySweetheart is offline "Decide you want it ƸӜƷ more than your afraid of it"Recognized Member Winner - $100
    Join Date
    Jul 2011
    Posts
    3,373
    Quote Originally Posted by oscarjones View Post
    Remember guys Adrenals relate to your blood sugar as well. For example, "a chocolate addiction" can be a symptom of adrenal problems. Or, if you ever wake up in the middle of the night at around 3-4 AM it can be be due to low nocturnal cortisol. Basically, cortisol reaches very low levels to the point where it causes hypogly***ia.

    Lets say you eat a sugary carb meal right before bed or very late in the evening, the instant high sugar (in a candy bar, let's assume) triggers a strong insulin response. If your adrenals aren't healthy they will not make enough cortisol, specifically at night, to raise your glucose after that big surge of insulin dropped it. When you have low blood sugar the body produces adrenaline, and it just so happens that around 3-4 AM is the body's normal time to have the naturally lowest glucose levels, partly due to fasting for 5+ hours.

    So basically, to recap, the reason you wake up, hypogly***ia causes production of adrenaline. And cortisol is responsible for helping to keep blood glucose stable via gluconeogenesis, which is the body's way of metabolizing glucose from non-carb sources, such as proteins and lipids.
    *her hands start to shake* chocolate... did someone say chocolate?!

    lol

  9. #49
    oscarjones is offline Banned
    Join Date
    Sep 2009
    Location
    USA
    Posts
    1,242
    Quote Originally Posted by Sexy4mySweetheart View Post
    *her hands start to shake* chocolate... did someone say chocolate?!

    lol
    I know! Nom nom nom... I want a chocolate factory.... bad..

  10. #50
    gbrice75's Avatar
    gbrice75 is offline AR's Diet Pimp! ~HOF~
    Join Date
    Nov 2009
    Location
    New Jersey
    Posts
    17,457
    Quote Originally Posted by oscarjones View Post
    Remember guys Adrenals relate to your blood sugar as well. For example, "a chocolate addiction" can be a symptom of adrenal problems. Or, if you ever wake up in the middle of the night at around 3-4 AM it can be be due to low nocturnal cortisol. Basically, cortisol reaches very low levels to the point where it causes hypogly***ia.

    Lets say you eat a sugary carb meal right before bed or very late in the evening, the instant high sugar (in a candy bar, let's assume) triggers a strong insulin response. If your adrenals aren't healthy they will not make enough cortisol, specifically at night, to raise your glucose after that big surge of insulin dropped it. When you have low blood sugar the body produces adrenaline, and it just so happens that around 3-4 AM is the body's normal time to have the naturally lowest glucose levels, partly due to fasting for 5+ hours.

    So basically, to recap, the reason you wake up, hypogly***ia causes production of adrenaline. And cortisol is responsible for helping to keep blood glucose stable via gluconeogenesis, which is the body's way of metabolizing glucose from non-carb sources, such as proteins and lipids.
    Spot on, great post. Exactly why haven't we changed your color yet?

  11. #51
    gbrice75's Avatar
    gbrice75 is offline AR's Diet Pimp! ~HOF~
    Join Date
    Nov 2009
    Location
    New Jersey
    Posts
    17,457
    Bump

  12. #52
    gbrice75's Avatar
    gbrice75 is offline AR's Diet Pimp! ~HOF~
    Join Date
    Nov 2009
    Location
    New Jersey
    Posts
    17,457
    Bump!

  13. #53
    RaginCajun's Avatar
    RaginCajun is online now Pissing Excellence!
    Join Date
    Jan 2011
    Location
    Deep Down South
    Posts
    22,924
    Just wanted to bump this
    Last edited by RaginCajun; 04-23-2013 at 07:51 PM.

  14. #54
    gbrice75's Avatar
    gbrice75 is offline AR's Diet Pimp! ~HOF~
    Join Date
    Nov 2009
    Location
    New Jersey
    Posts
    17,457
    Quote Originally Posted by 00ragincajun00
    Just wanted to bump this

    I think I have to this

    I need to go back thru and read this again and find ways to combat this
    Fasting
    Low/non existent sugar intake
    Supplement w/ chromium
    Supplement w/ cinnamon polyphenols
    Low-moderate carb intake
    Resistance training (to increase muscle cell sensitivity)

    To name a few. Good bump btw. Gonna have to read back through this again.

  15. #55
    RaginCajun's Avatar
    RaginCajun is online now Pissing Excellence!
    Join Date
    Jan 2011
    Location
    Deep Down South
    Posts
    22,924
    Quote Originally Posted by gbrice75

    Fasting
    Low/non existent sugar intake
    Supplement w/ chromium
    Supplement w/ cinnamon polyphenols
    Low-moderate carb intake
    Resistance training (to increase muscle cell sensitivity)

    To name a few. Good bump btw. Gonna have to read back through this again.
    Fasting is what I was thinking about trying again.

    Also been reading the benefits of green tea ECCG on insulin

    I also have a mean sweet tooth!

  16. #56
    gbrice75's Avatar
    gbrice75 is offline AR's Diet Pimp! ~HOF~
    Join Date
    Nov 2009
    Location
    New Jersey
    Posts
    17,457
    Quote Originally Posted by 00ragincajun00 View Post

    I also have a mean sweet tooth!
    Same here. However, indulging it *definitely* won't help either of us with increasing insulin sensitivity!

  17. #57
    RaginCajun's Avatar
    RaginCajun is online now Pissing Excellence!
    Join Date
    Jan 2011
    Location
    Deep Down South
    Posts
    22,924
    Quote Originally Posted by gbrice75

    Same here. However, indulging it *definitely* won't help either of us with increasing insulin sensitivity!
    Hahaha!

    Protein shakes help out and so does sugar free chocolate syrup! I always wonder if all that stuff has the same effect

  18. #58
    gbrice75's Avatar
    gbrice75 is offline AR's Diet Pimp! ~HOF~
    Join Date
    Nov 2009
    Location
    New Jersey
    Posts
    17,457
    Quote Originally Posted by 00ragincajun00 View Post
    Hahaha!

    Protein shakes help out and so does sugar free chocolate syrup! I always wonder if all that stuff has the same effect
    Me too, but I still use it in moderation, even during a cut. I'm making progress, so whatever.

  19. #59
    gearbox's Avatar
    gearbox is offline Knowledgeable Member
    Join Date
    Mar 2011
    Posts
    5,355
    Quote Originally Posted by 00ragincajun00 View Post

    Hahaha!

    Protein shakes help out and so does sugar free chocolate syrup! I always wonder if all that stuff has the same effect
    gbrice, 405, back in black, baseline, mk, ggr, kel, aust, etc etc..
    If you find out that is does effect insulin DO NOT TELL ME, LEAVE ME IN THE DARK!!
    gbrice75 likes this.

Page 2 of 2 FirstFirst 12

Thread Information

Users Browsing this Thread

There are currently 1 users browsing this thread. (0 members and 1 guests)

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •