Yes, i read that letro was more powerful than adex. But I have already purchased it and cash is short so I am going to have to use what I have.....So in order to not wipe out my estrogen I should take a lower dose of letro than .5 ed? Let me ask you this....how long of a time period should I initially take this letro. I think I would like to hit this estrogen problem hard at first (a week to 10 days) and them back off and find some sort of low maintenance dosage that meets my needs. I am looking for even, optimal levels. I am going to tell my doctor that since it costs $15/ shot, I want to take the shots at home. This way I can shoot a lower dose on a weekly basis instead of a 2 week roller coster ride at a higher dose. Anyway, these are some of my thoughts.