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04-17-2011, 01:51 PM #41Junior Member
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hey was wondering what ur results were bro?
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05-13-2011, 06:32 PM #42
naltrexone is an opiate blocker give to heroin addicts to stop them from being able to get high. It blocks receptors so that opiate drugs do not effect the brain and the user does not get high. I dont understand how this would relate to aas. Id love to know tho because i can get naltrexone all day long
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05-14-2011, 08:17 AM #43Associate Member
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The point of using Naltrexone on cycle is that if it can be shown to work by keeping the HPTA functioning, there will be no requirement for PCT, just stop talking your gear and your system will be functioning as normal.
The potential upside of this working is huge in terms of maintaining a functioning system.
Here is a great link to an article that talks about Naltrexone and other opioid antagonists effects on the HPTA.
http://www.primordialperformance.com...ppression.html
Below is a cut n past from one part of the article, Naloxone and Naltrexone a closely related in their effects.
Essentially, a u-opioid antagonist such as naloxone takes the brakes off of GnRH release and allows pulses of GnRH to occur as if no steroid hormones are present. (17) Naloxone, and related u-opioid antagonists have consistently proven to block the suppressive effects of testosterone, DHT, and estrogen administration in both animals and humans. (18-25) It also appears that these drugs have the ability to increase pituitary sensitivity to GnRH. (26,27)
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06-07-2011, 01:11 AM #44Associate Member
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Moment of truth is about to arrive.
Took my last pin 10 days ago, will continue to take Low dose Naltrexone as the system adjusts back to a life without AAs.
My cycle ended with Test C 450mg + Tren E 300mg / week.
Will do my best to keep a log of what happens over the next few weeks
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06-13-2011, 10:31 AM #45Associate Member
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Now at day 17 after my last pin.
Have been keeping a diary, have good sex drive at night and in the morning. Still managing a minimum of once a day and twice yesterday morning.
Still have some sweats from the remnants of the Tren, but they are diminishing / sometimes not there at all.
Still taking 25mg Aromasin each day, but getting worried that the Aromasin will be reducing my libido, so want to stop that soon.
Can feel that erections are not as long lived after I orgasm, but all is still working OK.
Not very clear on what to do next, I could start a PCT, but think I will keep going with the Low dose Naltrexone on its own for another week and see how things are then.
Feels to me like the Aromasin has made the Naltrexone slightlyless effective, but my balls have been around 80% inflated all the way through my cycle and are the same right now.
Be interested to hear if anyone has any thoughts on starting a PCT, clearly it would be best of all if no PCT was required, but not sure whether to give myself the potential grief of low Libido.
On my last cycle, Libido and the ability to sustain an erection started falling off by the start of PCT at 3 weeks, so am almost at that point just now, but sex twice yesterday morning and once again last night does not feel too much like my system is about to fail.
Looking at my notes, it took me 14 weeks after the end of my previous cycle to be able to orgasm normally and get full functionality back.
Any thoughts?
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06-23-2011, 12:21 AM #46Associate Member
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Now at day 25 after my last pin.
Managing sex every night with extra helpings on the weekend mornings.
The urge for sex is not as strong as when on cycle, so slower to start, but good and hard once going, also good wood every morning.
Stopped the Aromasin about a week ago
Still taking Naltexone each night although have missed the odd night at the weekends.
Nuts do not look completely inflated, but are in good shape.
Am on holiday next week, so will take Cialis with me, right now I would not need it, but might take it for extra fun.
Will continue with Naltrexone for at least the next couple of weeks, might start to taper it off after that, am feeling in the dark here, so not very sure what the strategy should be.
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07-02-2011, 12:04 PM #47Associate Member
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Now at day 34 after my last pin.
Managing sex every day
Been away on holiday, eating and drinking too much, so not absolutely certain how things are.
Gf started her period this afternoon, think I will start cutting back on the Naltrexone, will have one or two days off since she has just started, so might be able to judge something when getting no support.
Had wood on the plane for about an hour this afternoon, could not get rid of it, feeling like the system is working pretty well, although not 100% certain since I am not sure how much support I am getting from the Naltrexone.
Think on my last cycles I would be about the bottom of the chasm by now needing Viagra and struggling to orgasm.
This feels much much better.
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07-02-2011, 07:36 PM #48
Very interesting , can you get some bloodwork done?
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07-04-2011, 12:02 PM #49Associate Member
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I have not found a way to get blood work done in my area.
Not sure that blood work would be representative while I was taking Naltrexone.
Stopped taking Naltrexone on Saturday morning.
The half life of Naltrexone is 4 hours and 6-beta-naltrexol which is metabolised in the body from Naltrexone is 13 hours, so am guessing that there will not be much in the way of Naltrexone left in my system.
My gf is still on her period, but there is a fair chance she will be looking for action tonight, so this could be a bit of a big night for me if I can perform as normal without Naltrexone 5 weeks after my last pin.
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07-04-2011, 11:43 PM #50
Damn, guaging how sucessful naltrexone has been, based on erections alone is not good in my opinion. Bloodwork will show what you need to know, and how sucessfull/unsucessful it has been. Goodluck tonight
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07-05-2011, 03:20 AM #51Associate Member
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auslifta
Understand your interest in blood work, but seems to me that Naltrexone stimulates the HPTA which then stimulates the testes so that any readings taken will be skewed while on Naltrexone.
In the absence of blood work, the indicators of sexual function are for me the most interesting at this time :-
The ability to get hard and maintain an erection.
The ability to orgasm.
The size of your testes
Your mind playing tricks on you to limit your sexual performance.
You should be aware that my testes were about 70% to 80% inflated through the cycle and are still about that size just now. I took no HCG, only Naltrexone wile on cycle.
What I think has happened is that Naltrexone kept my HPTA functioning while on cycle. Once my cycle finished the Naltrexone has been keeping the HPTA and therefore my testes functioning while the AAS subside in my system.
Hopefully my system is now clear of AAS my body will start to correct the balance of hormones but is not capable of doing this instantly since my testes are still not fully inflated.
I have a spreadsheet that uses the half life of AAS, so will take a look at what the level of AAS in my system are just now and post that up.
Last night my system worked fine, I was good and hard and orgasmed as normal.
Pure guess, but I am hoping that after a few more days of being off Naltrexone my testes will inflate a bit more and my system will soon be back to normal.
My gf is pretty enthusiastic in the bedroom and enjoys nightly contact, so after last nights performance I have decided to completely stop taking Naltrexone.
Hopefully, it will not be long before I will know if my system is back to normal, but already I can see this is totally different to earlier cycles where I would be struggling with low libido and the ability to orgasm 5weeks after the last pin.
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07-05-2011, 10:47 AM #52
Still might be an idea to complete a low dose PCT, maybe some clomid/nolva?
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07-06-2011, 02:49 AM #53Associate Member
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Yup, thanks for that, have been thinking about a PCT, I have all the stuff on hand, however if Naltrexone has been keeping my HPTA active during my cycle, it may not be necessary to complete a PCT.
I will wait another week to see how my testes react to stopping Naltrexone and whether my sexual function is normal before deciding on whether to do a PCT.
If no PCT is necessary it will mean that Naltrexone does a great job in maintaining your HPTA functionality and a step change in the way we look after our body while on AAS.
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07-06-2011, 05:21 PM #54
Very interesting, please keep us posted.
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07-15-2011, 02:15 PM #55Associate Member
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7 weeks now since my last pin.
2 weeks since I stopped taking Naltrexone
Was a little worried through the week that my libido was a bit low, but maybe that was my mind playing tricks.
Had sex most days, noticed that I am staying hard long after I come, with no issues about coming which was a problem for me after earlier cycles.
Think I had good wood every morning, remember the wood being hard to get rid of some mornings.
Still not 100% certain that I am completely back to normal, but am very close, seems that my nuts are becoming slightly more inflated, not sure if they are completely back to full size, but again they are getting close.
Not really feeling like I need to do a PCT, can't imagine things slipping back from here, but will update this thread for a couple more weeks, but am thinking that it has been a complete success.
Badly sprained my ankle, started back on HGH 2 iu morning and 2 iu early evening 4 days on 3 days off through the week to see if that would help speed the repair, not sure if this will be having an effect on my libido, but I don't think it will be masking things.
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07-16-2011, 01:37 AM #56
So far great news, if I can get some for my first cycle I will report with full blood profile. Thanks for this.
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07-23-2011, 10:33 AM #57Associate Member
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8 weeks now since my last pin.
3 weeks since I stopped taking Naltrexone
My system seems to be working fine, I orgasm normally and my sex life is regular .
I am also feeling that my libido is a bit low, not alot, just a little and my nuts still feel a little undersized, so although I am more or less right, I have decided to do a short PCT.
Clomid makes me feel like shit, so will limit that.
Day 1 - Clomid 100mg + Tamox 40mg
Rest of week 1 daily intake - 50mg Clomid + Tamox 40mg
Week 2 daily intake - 50mg Clomid + Tamox 20mg
Week 3 daily intake - 25mg Clomid + Tamox 20mg
Not really sure how long a PCT to go for, but the above seems short and punchy enough.
I will keep reporting in and might change the PCT daily intake based on how I feel and how my Libido and how big my nuts are.
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08-08-2011, 01:56 PM #58Associate Member
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10 weeks now since my last pin.
5 weeks since I stopped taking Naltrexone
Felt $hit on Clomid these past two weeks, (know its Clomid since Tamoxifen has no sides for me) took 50ml Clomid and 40mg Tamoxifen for 12 days, then on to 25 mg Clomid + 20 mg Tamoxifen daily, been tired at night and low Libido.
Also supplementing 1800mg Ashwagandha extract and 1000mg Tribulus Terrestris per day.
Balls starting to look swollen, but have been looking undersize for quite allot of the last two weeks.
Not sure why my Libido is bad since it was fine before PCT, feels like PCT has dropped my Testosterone level as part of the process, no surprise though as its always like that.
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09-26-2011, 11:48 AM #59Associate Member
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Here is my wrap up of the Low dose Naltrexone experience.
I took Low Dose Naltrexone every day while on my 20 week Test + Deca finishing with Test E and Tren E cycle.
At the start there was a bit of experimentation to see if EoD would work and shifting the dose up and down.
I had difficulty in weighing the dose that I was taking until I bought some .001 gram weigh scales from eBay.
I started by grinding the tablets into a powder and dabbing a wet finger into the powder. Cutting the tablets into segments using a very sharp knife was the most effective way to get the dose that was required.
My Nuts were about 80 % of normal size throughout the cycle.
At the end of the cycle my libido was good and did not dive once the AAS wore off.
Unfortunately my nuts stayed the same size in the weeks after the cycle, I had hoped they would recover on their own.
7 weeks after the cycle my libido was reasonable but not 100%, so decided that I should do a 5 week PCT as follows:-
Week 1 50mg Clomid + 40mg Tamoxifen
Week 2to 5 25mg Clomid + 20mg Tamoxifen
Tribulus (Sopharma) 1g/ED
Ashwagandha RE 2g/ED9 weeks
Clomid kills me, I had desperately low Libido while on PCT, but my Nuts swelled up to about 120% of normal by the end of week 2, kept going with PCT for a further 3 weeks to be sure the PCT had worked.
By about two weeks after PCT my Libido was reasonable with no scary thoughts about will I manage or not.
Its now 4 weeks after my PCT and my nuts are still pretty swollen, so not sure how long that will last.
So to the million dollar question, did Naltrexone work and what will I do on my next cycle.
I feel that Naltrexone worked for me, evidenced by the fact that my Libido was reasonable 7 weeks post cycle without aPCT.
What protocol will I use on the next cycle.
I will use Naltrexone on the next cycle, but will supplement with small shots of HCG to keep my nuts at 100% normal size.
That might allow for no PCT at the end of the cycle.
I will give my body another couple of months off and start a shorter cycle in December, so fingers crossed that all works well.
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09-27-2011, 01:41 AM #60
Thanks for the update
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10-05-2011, 01:35 PM #62Associate Member
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