Low dose Naltrexone on next cycle

[Fit N Fun]

I am going to try low dose Naltrexone on my next cycle.

I tried it during my last PCT at 25mg/day and it had no obvious affect, there were also no side effects and I have seen a post by Swifto suggesting that side effects are normal.

Last Naltrexone was manufactured by Cooper pharma, got a different brand this time, so that might help.

Going to pre-load my system with large injections of Test and Deca on week one and will run 400 mg of Test and 400mg Deca every 5 days.

I will use the size of my testes as a guide to whether the Low dose Naltrexone is working, but am going to try 6mg late evening once every two days.

If the theory works, there will be a bounce in my system, keeping the testes working, about 4 hours after taking the Naltrexone.

Apparently larger doses of Naltrexone swamp the feedback loops and give no effect.

Got some HCG on hand so will revert to that if my nuts become too atrophied.

Will keep this thread updated as I go so that all will know of the progress taken.

Any questions let me have em!

[Ozstrongman]

I've never heard of this compound care to explain it briefly?

[Fit N Fun]

Here is a great discussion that say's it does not work

http://forums.steroid.com/showthread...one-discussion.

However, I tried Naltrexone on my last PCT and it has no side effects, so there is nothing to be lost by trying Naltrexone since I have HCG on hand, I have used HCG on my previous cycles, so am looking to replicate HCG performance on cycle and if this does not happen I will start HCG.

[Narkissos]

I'm curious to see how it'll work (or not work) for you.

[Fit N Fun]

Am just about to start my cycle, my tabs are 50mg so need to cut into 1/8th, am not sure whether to crush them and dissolve in water to simplify the dosing, or judge the volume by eye.

I have a pill cutter, but it is no good for this level of split.

Any thoughts?

[2jz_calgary]

Im starting my second cycle in about 3 weeks and will be taking 5mg of naltrexone eod. I'm going to try to weigh the pill out on a mg scale and see if I can get it to 5mg increments. I have 50mg tablets of naltrexone. (naltima)

[Fit N Fun]

2jz,

Started my Test and Deca cycle two weeks ago, I front loaded with the following, both the Test ( Sustanon ) and Deca are 300mg / ml.

Each line in the graph = 1 day



I also have the Naltima brand this time.

Am going to start naltrexone tonight, am going to crush the 50mg pills in a Mortar and Pestle and wet the tip of my finger to try and get a small amount on Naltrexone.

Going to take it every other day.

The other way I thought might work is to dissolve a tablet in a 2.5ml syringe of water and squirt some into juice. Think this would the most accurate way to deliver, but not sure if the Naltrexone will degrade in water.

[2jz_calgary]

Good luck let me know how it goes. I'll be a few weeks behind you with my cycle

[Fit N Fun]

No problem,

Already knew how bad Naltrexone tastes, but was still rubbish taking my fist "low dose" by dabbing a damp finger tip into a powdered tablet last night.

Am two weeks in to my cycle so have what feels like the start of atrophy, should not take long to work out if it is having an effect.

[2jz_calgary]

So how long in theory for naltrexone to have an effect on the hpta? Any bad sides yet? It can't taste worse than liquid clomid lol. If its so bad just gelcap it.

[Fit N Fun]

I have no idea how long it will take to show an effect, if at all.

My hope is that my nuts will retain their size and not show any sign of atrophy.

I have read a post by Swifto saying there are unpleasant side effects, but I already took Naltrexone at 25mg/day on my last PCT and can report there were no side effects. The manufacturer was Cooper Pharma, so either there was an issue with strength, or Swifto is wrong.

I have not gel capped anything, so would need to buy something to do that, how would you weigh out 5 or 6mg of powder to gel cap?

[2jz_calgary]

with a digital scale. Most have a mg setting.first weigh out a whole tablet to verify that it's 50 mg then weigh out 5 or 6 mg portions.get gelcaps from any healthfood store.

[Fit N Fun]

Bought a digital scale off ebay, so will be able to check how much powder I am getting on my wet finger tip.

Been thinking about the fact that it tastes so horrible, that might also mean that some of the Naltrexone is being absorbed by your tongue.

[2jz_calgary]

So do you feel that the naltrexone is keeping your hpta firing? Do you intend to use any hcg ?

[Fit N Fun]

I am having real problems getting the Naltrexone 50mg tabs cut down into 6mg portions.

The scale I bought from ebay reads down to 0.1gram and has some other settings which allow a reading to be taken, but its no good for measuring the powder down to that level, think I need a scale that will read down to 0.001 grams.

I have continued to wet my finger and get a good covering of the powdered tablet, I have started noting how many dips of my finger I am getting to see if I can work out the portion size.

Are my nuts fully inflated on Naltrexone, well to sum up.

Started Test + Deca with a preload dose on the 6th January followed by 450mg and 300mg every 5 days.

After two weeks I started Naltrexone at a wet fingertip of powder every two days.

A week later I am now on a Naltrexone wet fingertip every night at ~ 9pm.

My nuts are not full size, but I will see how things progress doing this nightly.

I am taking a reasonable amount of AA's so getting the HPTA to perform may require a nightly dose rather than a EO night dose.

I have HCG on hand, but right now I am not going to use it.

Could really do with some help on how to get a 6mg dose, let me know how you get your portion size organised

[2jz_calgary]

I havnt started just yet but what I will attempt later tonight is take a knife or razor blade and divide the 50mg tab into 10 even portions.this will give you 5mg denominations. How easy this will be remains to be seen but im sure ill be fine I have a nack for these things as I used to deal drugs lmao

[Fit N Fun]

OK, well I have a pill cutter and that was rubbish at making just one split, never mind several.

Be really good if you manage to do it.

Really need to look at the little research again to see what dose is best, I know it needs to be small so that it is out of your system after a few hours, apparently it is the spike in Naltrexone that the body reacts to.

[2jz_calgary]

Yeah I was able to do it. I used a really sharp knife and a flat cutting board. Just cut pill in half then half again then adjust...some portions may end up a bit less solid than others. It's a bit of a dick around but it only took me a few minutes tho divvy up one pill. Sho give it a try I think it beats tryin tho guage powder with a syringe.

[Fit N Fun]

Been on my cycle for 6 weeks now, have continued to use the 50 mg tablet crushed to powder, then dabbed my wet finger tip into the powder.

Started doing this every other night from about a week into the cycle.

After about 3 weeks of doing this I could see that my nuts were slightly atrophied and started taking Naltrexone every night at about 9pm.

Have recently started taking two finger dabs of the powder, its not very pleasant tasting so try and have plenty saliva in my mouth and swig a drink to get it over.

No idea whether it matters that some of the powder hangs around in your mouth, but I believe the idea is to get a Naltrexone spike that will make your HPTA react, so imagine that it is best if you can get it straight into your stomach.

It’s always hard to judge how atrophied you are, but would say my testes are about 70% of normal size. They are getting plenty of exercise so are not inflated through lack of use.

My weekly intake is 420mg Deca and 630 mg Test.

Have used HCG on all my previous cycles, so it’s hard to judge how well this is working.

Clearly there is a lot of experimentation here and I have not kept good records, but can see how many pills I have gone through from the start and it’s less than one a week (spilt some powder on the odd occasion too).

Am going to stick with it through the cycle and right now am not feeling the need to take any HCG.

[Swifto]

How are things now for you?

[Fit N Fun]

How are things now for you?

Am feeling pretty good, no side effects with the Naltrexone.

Am pretty sure my nuts would be well shrunk by now if there was no effect from the Naltrexone.

I am pretty hot most of the time, but that is what I expect from the level of Test and Deca I am running.

Really do not want to take any HCG since that will confuse the picture, just out of the shower and am sure my nuts are at least 70% of normal after 6 weeks on cycle.

Gear I am using is pretty active (Sciroxx), have lost lots of fat and starting to look pretty good, but am struggling with my diet to put on as much weight as I wanted.

Not sure what else to say, but ask away

[2jz_calgary]

Well is the naltrexone working or not? First off lost of articles say if you do nandralone based gear naltrexone is not of help. Do your balls shrink always? My first cycle was dbol and cyp which ended with prop at a high dose....never had noticable atrophy. Just seeking that valuble knowledge which you seem to lack. Not tryin to flame but from what youve said id just stick with hcg .

[Fit N Fun]

My cycles are always Test + Deca and will finish with Test + Tren and yes my balls shrink big time.

Just realised I did not state the point of Nalrexone is twofold.

1 On cycle it will keep your balls inflated, which may not seem that big of a deal since as you say you can use HCG.

2 The whole point of Naltrexone is that if it can be shown to work by keeping the HPTA functioning, there will be no requirement for PCT, just stop talking your gear and your system will be functioning as normal.

The potential upside of this working is huge in terms of maintaining a functioning system.

Perhaps Swifto can explain the above point more clearly, but this is not about looking for an alternative to HCG, it’s all about keeping your HPTA functioning normally during your cycle.

[2jz_calgary]

From all I've read I'm skeptical that naltrexone even works and im pretty sure you will not get away with no pct. I'm just concerned with adding another liver toxic compound to my cycle that may or may not work. Keep us all posted and I really hope it keeps your hpta 100% but i guess well see. Im still undecided if im going to use it or not.

[Fit N Fun]

Guess if you believe all that you read, there would be no way forward.

Am now 7 weeks into my cycle, so should have significant atrophy by now

Missed two nights Naltrexone over the weekend and could see that my nuts were well down tried taking smaller doses morning and night and my nuts are now back around the 70% of normal size again.

I am running completely blind on this, it would be nice if someone that understands the half life of Naltrexone could chip in.

OH and as far as I am aware your remarks on liver toxicity are wrong, Naltrexone is safer than Aspirin is how I have understood what I have read.

Have been trying to have lots of saliva in my mouth prior to licking the Naltrexone off my finger so that it gets into my stomach rather than linger in my mouth.

[2jz_calgary]

So are you taking it ed or eod?

[Fit N Fun]

For the first two weeks, I was taking Naltrexone every other day, but could see there was a bit of Atrophy starting, so decided to try taking every day which is what I have been doing most of the time, but missed some nights when I forgot to take it.

I have also tried it twice a day, but with a smaller dab of Naltrexone on my finger.

Because I have some atrophy, there is an opportunity to try different stuff to see what works best and I think that smaller doses might be better than bigger ones, but it is soo hard to judge the size of my nuts since they swell and shrink for no obvious reason throughout the day.

I am pretty certain that it’s small rises of Naltrexone in the body that is required since the 25mg/day I took on my last PCT did not appear to have much of an effect.

The half life of Naltrexone is 4 hours and 6-beta-naltrexol which is metabolised in the body from Naltrexone is 13 hours.

Here is a great link to an article that talks about Naltrexone and other opioid antagonists effects on the HPTA.

http://www.primordialperformance.com...ppression.html

Below is a cut n past from one part of the article, Naloxone and Naltrexone a closely related in their effects.

Essentially, a u-opioid antagonist such as naloxone takes the brakes off of GnRH release and allows pulses of GnRH to occur as if no steroid hormones are present. (17) Naloxone, and related u-opioid antagonists have consistently proven to block the suppressive effects of testosterone , DHT, and estrogen administration in both animals and humans. (18-25) It also appears that these drugs have the ability to increase pituitary sensitivity to GnRH. (26,27)

[2jz_calgary]

very interesting thanks for the info. most are quick to bash naltrexone as its an opiod antagonist...they assume we are heroine addicts or something. I still think you need to divy the pill up with a really sharp knife and get a good 5mg dose before bed. I divyed up my pill pretty good that way and have 10 equal parts. just my opinion good luck and ill keep you posted on what i do as im gonna start my cycle soon.

[Fit N Fun]

Not wanting to get anyones hopes up, but it appears to me that Naltrexone is working while on cycle.

My nuts were down a bit at the weekend, maybe I forgot to take one night, not sure.

On Monday and Tuesday I have been taking Naltrexone morning and night, and my nuts are right back up.

Points to note are that I am now crushing the tablet, not powdering the tablet which means much less bad taste in your mouth and probably better delivery of naltrexone to my stomach.

Also my girl friend is on her period for the last two days, so that has been two days rest for my nuts, so helping them to regain size more easily.

I have just crushed my seventh 50 mg tablet, this is day 56 of my cycle and I started taking Naltrexone two weeks into my cycle, so am averaging one 50 mg tablet per week = roughly 7mg / day on average

[2jz_calgary]

glad its working. Would you say it works better for you than hcg would at keeping atrophy at bay

[Fit N Fun]

Given that I am stabbing in the dark over how much Naltrexone to take each day and whether once a day or twice a day, or even every other day is the right thing to do, I would have to say it is nothing like as effective as HCG .

It’s only a matter of hours after an HCG injection that you will see a response in your nuts and the more HCG you take the bigger and quicker the response.

Right now I have some atrophy and am trying twice a day with a small dab of crushed Naltrexone on my finger, but I forgot to do it this morning which does not help things.

I am not too bothered about a little Atrophy, since this is how I run things previously when using HCG and if my nuts shrivelled up on this cycle, I would have no hesitation in starting HCG

The real proof of the pudding will be what happens when I end my cycle and will I need much of a PCT!!!!

[2jz_calgary]

interesting. I think i may use hcg and naltrexone for my cycle. Naltrexone @5mg eod before bed and hcg@250ius 3 times a week....see where that takes me for pct.

[Fit N Fun]

My nuts are pretty near full size right now, this has only been possible because I have experimented with the dose and timing of Naltrexone, if you use HCG , you will have no idea whether the Naltrexone is at the right dose for you and whatever cycle you are on.

For the record my girfriends period finished yesterday and I have had plenty of action over the last 24 hours, so the fact that they are well inflated can only be down to Naltrexone.

I was not at home to take any Naltrexone this morning, but I am going to take a small dose tonight, something near to 2 mg, I have the feeling that smaller doses gives a greater response.

[2jz_calgary]

lets get one thing straight....i dont give a shit what compound keeps my nuts goin....im not a lab rat in in this to win this. If both compounds keep me goin then great . Good log thaks for sharin i am going to use both. keep you posted

[Fit N Fun]

lets get one thing straight....i dont give a shit what compound keeps my nuts goin....im not a lab rat in in this to win this. If both compounds keep me goin then great . Good log thaks for sharin i am going to use both. keep you posted

I could care less whether you use HCG Naltrexone or both.

I offered you some friendly advice which has, as far as I am concerned, important information for you and you want to snap at me in reply, take your schoolboy antics elsewhere, they are insulting.

[BJJ]

any news?

[Fit N Fun]

Am continuing to experiment with the dose and the timings of Naltrexone.

I now have a set of gram scales that measure down to 0.001 grams so am able to weigh out a known amount of Naltrexone each night.

Stopped taking Naltrexone for a few days over the weekend to see what would happen to my testicles, they shrank down much like when you miss an HCG injection.

Started taking Naltrexone again on Monday night, it took about three days to get them back up to size again.

Have been looking at buying some gel capping equipment to put the Naltrexone into so that it gets all the way to my stomach. I am also taking quite allot of some vitamins each day, this may be having a combined effect on making the Naltrexone work.

Of course none of this yet proves whether I will not require a PCT, or minimise my PCT, the answer to that is still quite a few weeks away.

My current cycle is 450mg Sustanon and 300mg Deca every 5 days. I will be switching from Deca to Tren in a couple of weeks time, then will move to short half life Test, Tren and Bold for the last weeks of the cycle.

[EASTCOASTKID]

so I'm more curious more than anything, but is your goal to keep your nuts from shrinking or keeping your HPTA working because you know that you are talking about two different things here. Just because your nuts are normal size does not mean your HPTA is actively working. Again I'm not saying I know anything I am just curious.

[Fit N Fun]

so I'm more curious more than anything, but is your goal to keep your nuts from shrinking or keeping your HPTA working because you know that you are talking about two different things here. Just because your nuts are normal size does not mean your HPTA is actively working. Again I'm not saying I know anything I am just curious.

Good question EASTCOASTKID,

The goal with Naltrexone is to keep your HPTA (hypothalamic -pituitary-testicular axis) working throughout your cycle to minimise any PCT following the cycle.

I am using the size of my testicles as an indicator that Naltrexone is working while I am on cycle.

The real test will be what happens when my cycle has finished and how long to keep taking the Naltrexone.

A good indicator after my cycle, will be the quality of erections and whether I can orgasm since on my last cycle I had a real dip around 6 weeks post cycle, but all recovered nicely after that.

[Narkissos]

Good thread brother