Results 41 to 80 of 166
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01-19-2007, 09:16 PM #41Originally Posted by BigGuns101
Dieting: 3 (you; me; Faiz)
DNP : 20 000
We're not wanted on this thread BG
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01-19-2007, 09:21 PM #42Banned
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Originally Posted by Narkissos
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01-19-2007, 09:24 PM #43Banned
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Originally Posted by Narkissos
nope.. ignorant ppl dont listen
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01-19-2007, 09:25 PM #44Banned
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Originally Posted by FaizakaFez
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01-19-2007, 10:10 PM #45Originally Posted by FaizakaFez
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01-19-2007, 10:18 PM #46
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01-19-2007, 10:24 PM #47Senior Member
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Hey ... uh, Nark!? Do you have rational for disliking DNP ? Because... if not DNP - I don't know a safer more effective means of weight loss. This is about using chemicals and synthetics to get an edge. Ephedra isn't safer in a fat loss dosage. For those who aren't the unlucky ones that are allergic to it... I can't imagine a better option if chemicals are the method of choice. Do you have any real cases of someone doing 500mg or less of DNP and having a serious health risk? And more importantly, to those who think that the risks of Andrenergic drugs are safer - well, I guess you get to find out in 20-ish years when you get a cardiogram.
Additionally ... FAKE DNP? RIDICULOUS! Nothing is going to mimic the results of DNP. Now, real DNP may not be the issue ... it may be the filler used...
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01-19-2007, 10:35 PM #48
Diet? What's that ...When you can just take dnp
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01-19-2007, 10:50 PM #49Originally Posted by Two4the$$
I bestow on you the pleasure of going through my posts til you find the reason(s)..as i'm not going to type that up yet again.
Originally Posted by Two4the$$
'This' is about lacking discipline.
In the same manner that AAS use (to which this forum is dedicated) comes with an assumed responsibility... the use of any other ergogenic requires such.
Originally Posted by Two4the$$
Originally Posted by Two4the$$
Originally Posted by Two4the$$
To name one affliction i've had post-use: DNP affected my vision... That was serious to me.
I used it once.. and for 7 days solely.
I wrote one of the DNP profiles used on the message boards.. so to question my anxillary use (anti-oxidants etc.) would be laughable.
I have friends who have used the compound and been negatively affected.
The 'seriousness' of an affliction is determined by the value assigned to it by the affected individual.
It is amusing how safe so many people claim this compound to be...
I'll reserve judgement when someone can show me a subgroup of individuals who have done it on and off for decades.
Until then...'safe' is laughable.
Until then.. 'safe' is speculation.
Laughable speculation.
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01-19-2007, 10:56 PM #50Originally Posted by Narkissos
It's an AR double standard.
A 135 lb 6 footer will ask for cycle advice..and SVT'll say: "You don't need gear.. you need to EAT"
Now look at this...
A 20 year old non-obese (16% bf) individual on DNP ?
Nark says: "You need to eat.. PROPERLY"
Review his threads.
I need a simple, low carb cutting diet. etc. etc.
He's not the only college kid here.
He started to diet just a month ago.
And he proposed starting clen at this point.
He needs to stop making excuses..and put in the work.
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01-19-2007, 11:04 PM #51Banned
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Originally Posted by Narkissos
You got i all wrong Corey, it's his genetics...RE BELOW
It's god given genetic love handles man, it sucks I've tried all sorts of diets and stuff not, but lets see if DNP gets rid of these. The only place i'm carrying any excessive fat is in the love handle, my legs/arms/upper chest are solid, and i even have upper abs.
It's cold outside, but hot inside! Dnp Log!
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01-19-2007, 11:11 PM #52
^^Yes dear Faiz.. His body has magically changed its fat distribution pattern. Thus bodyfat deposition is no longer systemic.. it is isolated to his love handles.
Let's leave him and his thread alone.
I know i'm done with it...
Good luck SVT
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01-19-2007, 11:42 PM #53
Well said !!!
Originally Posted by Two4the$$
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01-20-2007, 03:59 AM #54Senior Member
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For one thing, the chemical companies using it in paint have never been sued. Secondly, employees using it as pesticide have never sued companies they worked for - despite multi-decade long exposure.
The increase in cataracts was correlated to its FDA ban, and then never backed up by any empirical evidence to validate the idea.
When I say "fat loss dosage" vs. energy supplement dosage of ephedrine, most will know what I mean - and you may elect to act as though you don’t... but long before you perceive this as something you should take offense to, let me clarify one thing. I'm challenging you for the sake of coming away enlightened ... if you have a thread to show me, please send me the link, no need to repost or rewrite. You write well, you're clearly immersed in this subject, and you hold some views that are based on your judgment, and it is clearly anchored to your perception of “acceptable risks.”
It's stated that the effect of AAS on LDL and HDL adversely affect your likelihood of coronary related disease.. And as it stands, that disease is responsible for upwards of 40% of all deaths. That isn’t to mention a myriad of other possibly legitimate issues this VAIN pursuit may yield.
Point is ... it's no less ludicrous to deem AAS safe than it is to deem DNP, or recreational drugs of any sort safe. People die from general anesthesia. General anesthesia is used in many elective surgical procedures. It is legal to do them in all countries I know of. No one anywhere is in an uproar, and the FDA isn’t regarding it as an epidemic.
Perception is reality, and society has manufactured a construct for us to perceive the baseline of morality, and risk.
Did you know the DEA in the US was CREATED in response to the assumed association between the protesters of Vietnam war and LSD use? And that the effects of drugs were used as justification to stamp out protest?
Look ... you make a lot of sense - but you're on a moral high horse just because you're more disciplined than most are. Maybe this is your job... many people show up to work on time... and speaking of which, status drive is another example of how people differentiate themselves. It isn't passed out equally amongst all – it’s an issue of genetic quality in many respects.
Either way... with all due respect, I'll read further in to your stance on things... Given the number of posts you’ve made, please make it easier and send me the link…
And incidentally, Nolvadex will adversely affect your vision, too.
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01-20-2007, 04:48 AM #55
How's it going SVT, I tell you, on 500mg yesterday I sweated my balls off all night, I woke up drenched, and thats without my heating on.
Seems to be working
I can't figure out why I seem to have lost no weight though, I must be a water balloon right now. I'll reweigh myself today when I'm at the gym...hopefully I'm finally lighter.
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01-20-2007, 07:46 AM #56Originally Posted by Two4the$$
This is copy and paste.
Not only has not a single test found it to be carcinogenic, but test after tyest after test find that DNP actually ATTACKS cancer cells, and helps anti-cancer medications work better, and helps anti-leukemia medications work without destroying cell DNA, and suppresses tumor growth by 20-50%. The summaries are all right here, friends. Karma me up!
DNP is Ames negative, and does not promote tumors. See for yourself at http://toxnet.nlm.nih.gov/
http://www.epa.gov/ttn/atw/hlthef/dinitrop.html reports on health risks. While there have not been human studies, animal studies found no cancers caused by DNP administration. It is considered a toxin because it causes nausea, sweating, and weight loss.
http://www.cyberiron.com/drugs/dinitrophenol.html reports on halth risks from external exposue. In other words, don’t get it in your eyes, or on your skin if you’re allergic. Pretty elementary stuff.
http://www.ebec2000.com/abstracts/056.htm This animal study documents a 64% increase in metabolism. "These findings confirm that DNP effectively increases metabolic rate..." Duh.
http://www.zymed.com/pdf/04-xxxx/04-8300.pdf A PDF file about an antidote to DNP.
http://www.boehringer-ingelheim.es/...glesa/cap13.htm finds that DNP did not activate liver enzymes (MAT) associated with liver damage
"Comparative study of toxicity of 4-nitrophenol and 2,4-dinitrophenol in newborn and young rats." Koizumi M, Yamamoto Y, Ito Y, Takano M, Enami T, Kamata E, Hasegawa R. Division of Risk Assessment, National Institute of Health Sciences, 1-18-1 Kamiyoga, Setagaya-ku, Tokyo 158-8501, Japan. This study found that DNP can induce death in overdosed amounts, but that up to that point no toxicity was evident, nor were there any abnormalities in physical development.
"Phenol toxicity and conjugation in human colonic epithelial cells." Pedersen G, Brynskov J, Saermark T. Dept of Medical Gastroenterology, Herlev University Hospital, Copenhagen, Denmark.. This study found that DNP has a toxic effect on cells of the colon, with "toxic" defined in two ways: first, it interfered with metabolism (this we know—it’s the intended effect of DNP users!) and second, it interfered with bowel inflammation (not a health risk. This is caused by osmotic effect, with the worst results being softened stools and gas).
"Mechanisms of bacterial resistance to macrolide antibiotics." Nakajima Y. Division of Microbiology, Hokkaido College of Pharmacy, 7-1 Katsuraoka-cho, Otaru, Hokkaido 047-0264, Japan. This study found that antibiotic-resistant bacteria could be thwarted with DNP. "the extent of the accumulated drug in a resistant cell increases as much as that in a susceptible cell in the presence of an uncoupling agent such as…2,4-dinitrophenol (DNP)."
"Absence of Crabtree effect in human melanoma cells adapted to growth at low pH: reversal by respiratory inhibitors." Burd R, Wachsberger PR, Biaglow JE, Wahl ML, Lee I, Leeper DB. Departments of Radiation Oncology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA. Check this out—DNP actually helps make melanoma tumors easier to attack by increasing ratio of oxygen consumption to lactic acid production, while glycolysis remains the same. "Therefore, tumor acute acidification and oxygenation can be achieved by exposure…"
"New insights in the cellular processing of platinum antitumor compounds, using fluorophore-labeled platinum complexes and digital fluorescence microscopy."
Molenaar C, Teuben JM, Heetebrij RJ, Tanke HJ, Reedijk J. Department of Molecular Cell Biology, Leiden University Medical Centre, The Netherlands. DNP is used as a control in tests of antitumor cells because it does NOT bind to cell DNA, nor promote tumors, yet its staining abilities enable tracking of the uptake of antitumor drugs.
Specific inhibition of breast cancer cells by antisense poly-DNP-oligoribonucleotides and targeted apoptosis." Ru K, Taub ML, Wang JH. Department of Biochemistry, State University of New York, Buffalo 14260-3000, USA Are you ready for this? DNP actually INHIBITS (!!!) breast cancers! Yes, not only does it NOT promote cancers, it’s being recognized as a cancer-fighter/blocker. "Two membrane-permeable and RNase-resistant antisense poly-2'-O-(2,4-dinitrophenyl)-oligoribonucleotides (poly-DNP-RNAs) have been synthesized as inhibitors of human breast cancer…fluorescence assay indicates that the targeted antisense inhibition by poly-DNP-RNAs leads to apoptosis of SK-Br-3 cells but does not affect nontumorigenic MCF-10A cells. The control poly-DNP-RNAs with random or sense nucleotide sequence are completely inactive." Plain English? DNP can be synthesized as an anti-cancer compound, because tests show that it blocks mutagens but does NOT affect non-mutagenic (healthy) cells, and has no RNA effects on them.
"Heat shock protein induction by certain chemical stressors is correlated with their cytotoxicity, lipophilicity and protein-denaturing capacity." Neuhaus-Steinmetz U, Rensing L. Institute of Cell Biology, Biochemistry and Biotechnology, NW II University of Bremen, Germany. The thermic effect of DNP induces protein synthesis (heat shock protein, or HSP, synthesis). In fact, it’s quite GOOD at it: "ASA, DNP and CCCP induced HSP at lower concentrations than substances with a similar lipophilicity…"
"Comparative effects of the metabolic inhibitors 2,4-dinitrophenol and iodoacetate on mouse neuroblastoma cells in vitro." Andres MI, Repetto G, Sanz P, Repetto M.
National Institute of Toxicology, Seville, Spain. In this study, DNP’s observed effect was an increase in metabolism (duh!), while the other toxins compared to it had harmful in vitro effects but no increase in metabolism.
"Inhibition of uncoupled respiration in tumor cells. A possible role of mitochondrial Ca2+ efflux." Gabai VL.Medical Radiology Research Center, Russian Academy of Medical Sciences, Obninsk. DNP not only does not cause tumors, but it inhibited their respiration by 20-25% compared to controls.
"Amsacrine-induced lesions in DNA and their modulation by novobiocin and 2,4-dinitrophenol." Shibuya ML, Buddenbaum WE, Don AL, Utsumi H, Suciu D, Kosaka T, Elkind MM. Department of Radiology and Radiation Biology, Colorado State University, Fort Collins 80523. In this study, researchers found that DNP abrogates—or disrupts—cytotoxicity in hamsters (using cancerous cells). They expected to find that DNP would interfere with anticancer treatments, but instead found that DNP increased their effects. They state, though, that they cannot claim a proven effect of DNP on anticancer treatments yet, although they do agree that treatment with DNP actually enhanced the effects of the DNA regenerative therapy of anticancer chemotherapy.
"Induction of endonucleolytic DNA cleavage in human acute myelogenous leukemia cells by etoposide, camptothecin, and other cytotoxic anticancer drugs: a cautionary note." Kaufmann SH. Oncology Center, Johns Hopkins Hospital, Baltimore, Maryland 21205. The authors warn that certain anti-leukemia drugs resulted in "extensive DNA degradation." BUT (good ol’ DNP to the rescue!), "Preincubation with dinitrophenol abolished the effect…"
"[Dependence of the nature of the action of metabolic inhibitors on ribosomal RNA synthesis in Ehrlich ascites carcinoma cells on cell integrity]" [Article in Russian] Akhlynina TV, Buzhurina IM, Panov MA, Rozovskaia IA, Chernaia NG. DNP actually inhibits the synthesis of RNA in carcinoma cells. In other words, it helps cancerous cells commit suicide by neutering themselves. "Ribosomal RNA (rRNA) synthesis in the intact Ehrlich ascite carcinoma cells is selectively inhibited by papaverin (ED50 = 0.01 mM), 2,4-dinitrophenol (DPN; ED50 = 5 microM), and actinomycin D (ED50 = 0.1 microgram/ml)."
"Autocatabolism of surface macromolecules shed by human melanoma cells." Bystryn JC, Perlstein J. Cancer Res 1982 Jun;42(6):2232-7. This study finds that DNP helps melanoma cells die (autocatabolize) while other cells are unaffected.
http://www.geocities.com/byggdegstor/dnpforside - tons of research, including medical studies. Excerpts:
DNP does not cause liver damage: "Their analyses demonstrate, beyond a doubt, that the liver does not suffer any damage in the course of dinitro treatment." (Biological Study of Dinitro Drugs in Humans By Dr. Jacques Bell. Bell, Jacques. 1939. Etude biologique des produits dinitres chez l'homme. Medecine. 19:749-54. Translation © 1996 Robert Ames)
Also: "Experimental studies on animals do not show toxic effects of dinitrophenol on the kidney. Anatomical-pathological examinations of animals, even those which died from a massive dose of dinitrophenol, do not reveal any important anatomical changes, except a small degree of cytolysis. Clinical documents are not abundant, but, on the whole, do not seem to demonstrate that dinitrophenol is toxic for the kidneys."
"Dinitrophenol has almost no action on the blood cholesterol. (Grant and Schube)."
"it doesn't seem that dinitrophenol at usual clinical doses is likely to harm the kidneys."
"Dinitrophenol is remarkable for its absence of effect on the cardio-vascular system...dinitrophenol is absolutely devoid of toxicity for the heart."
"Dinitrophenol does not attack cell tissue albumin and does not determine the fat loss to the expense of the muscles, contrary to thyroxine."
"dinitrophenol offers this precious advantage that the cessation of its use at the slightest appearance of signs indicating an imminence of intoxication results immediately in the arrest of those symptoms." (Professor Pouchet)."
Interestingly, one medical theory on a health ADVANTAGE of DNP is that the slight increase in thermogenic temperature simulates the fever a body induces during a viral attack. The body increases itsheat to protect organs but kill viruses, and some theorize that DNP can do the same thing, thus killing viruses in the body. In this mechanism, DNP may have an immune-enhancing effect.
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01-20-2007, 08:49 AM #57Banned
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Originally Posted by Narkissos
Day 4, nothing. Did 40 minutes of cardio in the AM, but I was itchy as hell last night sleeping, I dunno if that has anything to do with the compound, maybe i just forgot to shower
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01-20-2007, 09:30 AM #58Originally Posted by SVTMuscle
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01-20-2007, 09:34 AM #59Originally Posted by Snrfmaster
Now do you believe me??
PS. I was in Gloucester Wednesday, I could see a trail of sweat through the town centre!! You??
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01-20-2007, 12:35 PM #60Originally Posted by Snrfmaster
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01-20-2007, 10:17 PM #61Banned
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End of day 4, took another 250mg around 5pm, still feel nothing, just itchy.
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01-20-2007, 10:27 PM #62
to decimate posts 54; 56; and 57.. or not.. hm..
Nah.. it isn't worth it.
I'll just add (again)...
Good luck SVT.
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01-20-2007, 10:39 PM #63Banned
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Do you mean that, or just saying that to be a good mod?
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01-20-2007, 10:47 PM #64
@ 'Good Mod'.
I'm Vet; VIP; Mod and Supermod elsewhere... so i have no reason to feign sincerity. Certainly not to hold a position lol.
I'm always serious when i post here.. regardless of if it's in the lounge or steroid forum.
So while i dislike your attitude and the persona you project on the boards..I sincerely hope that you get what you're looking for out of this... or at the very least, that you don't fuck yourself up.
Bodybuilding is a lifestyle choice... a sum of steps.
At 20 years old i'd hope you realise that you're at the beginning..and that you should try to enjoy the journey.
What i've learnt is that these 'quick fixes' really fix nothing.
Narkissos
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01-20-2007, 10:51 PM #65Senior Member
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Originally Posted by SVTMuscle
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01-20-2007, 11:08 PM #66Originally Posted by Two4the$$
I will concede however that i do have contradictory information..and you are right in a sense.. in that i do not rank typing up an article of the length deemed necessary for a rebuttal...and referencing it in my usual style, among my "top 100 fun things to do tonight"
SVT i got your PM..and you have a reply
Nark
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01-20-2007, 11:21 PM #672/3 Deca 1/3 Test
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Not to be a prick but, don't ya think Narkissos kinda has a point SVT?
Maybe you haven't actuallly been busting your ass as hard as you thought? Or wouldn't you have achieved your goal by now? I know that happens to me, well all the time really, I look back and think "I could've done more" Or "I need to try harder" though at the time I thought I was giving it my all. It helps to be your own worste critic, to keep moving forward, demanding more and more of yourself, IMO.
I know Narkissos isn't easy to "get along with" at times perhaps but he may be giving you just what you need....the brutal truth.
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01-20-2007, 11:23 PM #68Banned
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01-20-2007, 11:25 PM #692/3 Deca 1/3 Test
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Originally Posted by SVTMuscle
Well it is still pretty harsh but I am glad to see you at least not jumping into a gram of tren.
I do wish you luck regardless.
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01-21-2007, 12:20 AM #70Senior Member
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Nark! Dude... Just a link. You said you've typed it out prior to this to an exhaustive degree.
Again... I'm not trying to measure d1cks, nor to be one - I'm just trying to say whatever I have to say to get you to disclose the basis of your opinion. I researched this compound extensively, and I've looked for anything that would sway my POV on it.
The majority of posts with the stance of ... OMG, DNP almost KILLED ME! are based on BB's who regard a day spent not growing a day of life wasted. They do what I'd regard as a "megadose" run of this stuff ... and it's nothing to be triffled with. I wholeheartedly respect it, and follow the protocol that PhD's used when treating for obesity.
Calorie restrict to a moderate diet.
Run 200 - 300mg ED for extended periods of time.
Take supplements as needed (vit, mineral, shit like that)
Possibly take t3.
Results? After a year one guy lost 125 pounds; this is interesting because although he was 250lbs, and had the discipline that likely causes such obesity... he was able to achieve a drastic change in composition that even liposuction couldn't yeild more safely. 1mg per pound is an EXTREMELY light dose, and should actually enable someone to be adequately productive so long as they aren't in college, supporting themself, and taking a heavy load of classes. They extend the period, not the dose. Where as amongst the BB community ... people are in a rush to do A LOT per day, so long as they minimize the duration. Why? I can't explain it. But I think it's that methodology that has resulted in the disposition the average guy holds.
Funny, probably more people on here using insulin than DNP ... And I can't imagine even need to reiterate which is more dangerous.
What ever combination of words needed to get you to post up either some references, or just the link in which you state the cause of your opinion ... please assume I've said them, and reply accordingly.
Thanks
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01-21-2007, 05:05 AM #71Originally Posted by Narkissos
I thought you were done with this thread? I don't see anyone here who wants your input.
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01-21-2007, 06:18 AM #72Originally Posted by Snrfmaster
DNP causes such controversy!
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01-21-2007, 07:36 AM #73Banned
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Not when I've been on it for 5 days and felt nothing and no change in weight
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01-21-2007, 08:23 AM #74Originally Posted by SVTMuscle
As I said to Snrfmaster....
Have patience!!
Your body water content will be much higher than normal by now, the weight you've lost is offset by this increase in water weight. Are you on 500mg now??
What is happening to you happened in exactly the same way to Snrfmaster, drop him a PM and he will explain.
He's on same stuff as you!!
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01-21-2007, 10:47 AM #75Banned
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Good energy, not warm at all mid day 5. itch as hell though its pissing me off!!! I feel like i got fleas!
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01-21-2007, 10:57 AM #76
I never got any itching, might wanna try benadryl or something similar, could be an allergic reaction.
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01-21-2007, 10:57 AM #77Banned
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By day 5, it will have reached 90% of the steady state blood levels and guess you did not carb deplete.This is normal.Would like to see more cardio,and longer periods.
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01-21-2007, 11:05 AM #78Banned
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I was told not to carb deplete!?! According to Anthony Roberts book it said to be sure to keep carbs regular if not higher!
I mean, im not crazy itchy, just alot more than normal. Not red or anything
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01-21-2007, 11:06 AM #79Banned
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Originally Posted by steroid profile for DNP
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01-21-2007, 11:30 AM #80Banned
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My point is that your complaining about no results with fat loss. DNP will take a good 3-4 days to deplete the body's glycogen stores before it can efficiently burn stored fat and feel it`s effect.Thats why if your a very advanced user front loading is the best form of attack,I dont recommend this for newbs.With your low dose and the quality of DNP you have,just be patient.
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