Estrogen, Prolactin, Progesterone Management + Gynecomastia Prevention & Reversal

[devil-1986]

How old are you and what is your body fat percentage? Your testosterone to estrogen ratio makes sense.

28 yro and 12 % body fat

[austinite]

Interesting results. Try...

DIM @ 400mg
Zinc @ 50mg
Copper at 3mg

[devil-1986]

what is DIM ?

[devil-1986]

Interesting results. Try...

DIM @ 400mg
Zinc @ 50mg
Copper at 3mg

what is DIM ?

[austinite]

3,3'-Diindolylmethane

[Igifuno]

DIM (Diindolylmethane): is a powerful component found naturally in cruciferous vegetables that balances estrogen metabolism. Many of the health problems commonly associated with estrogen and testosterone are actually linked to hormone imbalance and unhealthy hormone metabolism. DIM helps regulate estrogen hormone metabolism, which can be beneficial for breast, uterine, cervical, and prostate health. Achieve healthy estrogen metabolism today.

Source: BIO response . com
BioResponse DIM Supplement for Estrogen Hormone Balance: Dr. Zeligs Bioavailable Patented Diindolylmethane

[devil-1986]

How long and what time of the day must be use ?

[austinite]

Doesn't matter. Just take it around the same time daily. Try it for 6 to 8 weeks and then test your levels again. If these are your baselines, you just have a hypersensitive HPTA and there probably isnt any permanent solution. Your body is likely adjusted to these levels and they are not harmful. But you can always visit an endocrinologist to discuss any concerns.

[devil-1986]

Doesn't matter. Just take it around the same time daily. Try it for 6 to 8 weeks and then test your levels again. If these are your baselines, you just have a hypersensitive HPTA and there probably isnt any permanent solution. Your body is likely adjusted to these levels and they are not harmful. But you can always visit an endocrinologist to discuss any concerns.

thanks alot dear austinie you awesome
have a powerfull day

[austinite]

thanks alot dear austinie you awesome
have a powerfull day

You're awesome! Powerful day to you too, sir!

[CaptainDwamn]

Would Ralo or Tamo help reverse Gyno in someone who hasn't taken anabolics?

[austinite]

Would Ralo or Tamo help reverse Gyno in someone who hasn't taken anabolics?

yes.

[kelkel]

You awesome!

[AliYousaf]

Hello Austi.. Great info there. I was wondering if you good shed some light on Brimocriptine compound.. My first choice would be Cabergoline, as I am about to add Deca in my current cycle from the next week and can't seem to find anywhere. I BUY MY STUFF OTC.. But Dostinex wasn't available anywhere so I bought Bromocriptine Mesylate 2.5 mg a tab.
Could you please tell how to use it in the cycle or add to the main article about this one too so others could benefit too, please. I'll be using 200 mg Deca with 500 mg Test e with .25 mg adex ed.
Thanks.

Sent from my iPhone.

[devil-1986]

what was estrogen and estradiol range or level could be dangerous for a 28 yld male ?

[devil-1986]

what was letro dosage took you from 47 ng/dL to 2 ng/dL in 10 days ?

[austinite]

what was estrogen and estradiol range or level could be dangerous for a 28 yld male ?

Don't understand. Just look at your blood work, it will give you range if that's what you mean.

Hello Austi.. Great info there. I was wondering if you good shed some light on Brimocriptine compound.. My first choice would be Cabergoline, as I am about to add Deca in my current cycle from the next week and can't seem to find anywhere. I BUY MY STUFF OTC.. But Dostinex wasn't available anywhere so I bought Bromocriptine Mesylate 2.5 mg a tab.
Could you please tell how to use it in the cycle or add to the main article about this one too so others could benefit too, please. I'll be using 200 mg Deca with 500 mg Test e with .25 mg adex ed.
Thanks.

Sent from my iPhone.

I haent used bromo.

what was letro dosage took you from 47 ng/dL to 2 ng/dL in 10 days ?

100 mcg.

[devil-1986]

if some one have gyno and then decided to solve this issue with raloxifen then with 60 mg daily use of raloxifen can either taking back his estradiol level to the safe range ?

[austinite]

if some one have gyno and then decided to solve this issue with raloxifen then with 60 mg daily use of raloxifen can either taking back his estradiol level to the safe range ?

Possible. Everyone is different. It will work mostly at breast tissue because that's where it binds to the E receptor more than any other, may not effect overall E2. Needs blood work.

[devil-1986]

Possible. Everyone is different. It will work mostly at breast tissue because that's where it binds to the E receptor more than any other, may not effect overall E2. Needs blood work.

thank you dear austinite thats very useful . and sorry for my language

have a powerful day

[austinite]

no problem. You have a powerful day as well

[uvafan4life2]

I just read threw your educational threads aust and i am so grateful i came upon them. thank you (:

[havanakid]

Bump….Excellent read Austinite.Good job as usual buddy.

[tebby]

It should be put in the Bible between Ephesians and Phillipians...
so many moving gears to pay attention to and after reading this 3 or 4 times, I know exactly what to do and what to NOT do.
Well written too. Seems we have some experience writing "method and materials" stuff
Thanks for you effort here Austinite

[Firefighter33]

Well Austinite, what can I say ?? You're The Teacher !!
I lived wrong the last 20 years? Yes, because I don't know a lot of the info that you posted here.
Thank you so much!!
A big hug from South America.........
FF

[Slacker78]

Great Austinite, thank you.

2 questions:

1) To reduce estrogen activity caused by an high progesterone level, we could use AI. Instead, to manage high level of progesterone ( which caused side effects you told ), what could we use ?

Maybe the progesterone side effects are indirectly through increasing estrogens activity..... isn'it ?

2) 19-Nor compounds ( progestins ) cause increasing progesterone level ( and so activate more receptors ) through up-regulations due of progestins binding on them, or just directly through the action to binding to them ?

[PBJtime]

Solid read

[austinite]

Great Austinite, thank you.

2 questions:

1) To reduce estrogen activity caused by an high progesterone level, we could use AI. Instead, to manage high level of progesterone ( which caused side effects you told ), what could we use ?

Maybe the progesterone side effects are indirectly through increasing estrogens activity..... isn'it ?

2) 19-Nor compounds ( progestins ) cause increasing progesterone level ( and so activate more receptors ) through up-regulations due of progestins binding on them, or just directly through the action to binding to them ?

1... You can use SPRMs (selective progesterone receptor modulators). Not recommended without a doctors orders and no need for it if you monitor your blood and control E2. That's your first line of defense. If you cannot control Progestins, lower your dose or discontinue use. Control E2 and monitor blood work is the only answer I have for that question.

2... I can't make sense of this question, please rephrase.

[Slacker78]

1... You can use SPRMs (selective progesterone receptor modulators). Not recommended without a doctors orders and no need for it if you monitor your blood and control E2. That's your first line of defense. If you cannot control Progestins, lower your dose or discontinue use. Control E2 and monitor blood work is the only answer I have for that question.

2... I can't make sense of this question, please rephrase.

Thank you Austinite. In order:

1) You said "If you cannot control progestins"..... as the side effects as you told, are given by E2 in presence of progestins, i assume that it'is like say "If you cannot control E2 in progestins presence, lower progestins"... is it correct ?

2) Some folks tell that progestins don't buildup estrogens count but just increasing their activity level.... if it's so, using progestins, might i expect in blood work a E2 it's within range despite i'm suffering high estrogens symptons ? Maybe i wrong, but if the estrogens count remain unchanged and increase just its activity level, it should be hard to expect blood work be reliable, given the problem is not in E2 count but in its activity, increased by progestins....

3) The question you didn't understand ( be patience for my English ) tell about how 19-Nor compounds ( progestins ) act against their receptors. You told in your article, that progestins *activate* too many receptors, increasing progesterone activity. Now i wonder if progestins hook their receptors "agonisting" them increasing directly progesterone/estrogens activity *OR* hook receptors "antagonizing" them and promoting receptors UP-REGULATION of the same, which result in an increased receptors number where NATURAL PROGESTERONE could hook, raising in this indirect way, estrogens activity. I know it seems a bit twisted... but i love technical details...

I thank you so much in advance for your time and the knowledge you offer to us through your passion. THANKS A LOT.

[Slacker78]

I think i did too much hard ( or silly ) questions... :P

[austinite]

No. Your questions Are answered and there is a difficult language barrier.

[Slacker78]

No. Your questions Are answered and there is a difficult language barrier.

Sorry Austinite. But i don't think, in particular 2 and 3 questions are already answered ( let me know where the core of their real meaning is clarified elsewhere ). Neither, i don't think there's a so much hard language barrier such to make a pharaonic work, going a little in deep about the underlying mechanism how progestins affect E2. I'm not interested in a full endocrinology lesson. But i accept what you think it about, although i do not share it.

Thank you all the same, and forgive my reply.

[jdpeters]

I am still on cycle with a slight gyno flare up. I've been using liquid dex since the start but didn't seem to keep estrogen levels down. Switched to stane, not noticing much of a difference. Was thinking about Letro but after reading the article thinking against it. Can I use Tamoxifen during cycle for reduction in gyno and also continue to use it for PCT with Clomid after cycle?

Thanks for the write up Austinite!

JP

[austinite]

I am still on cycle with a slight gyno flare up. I've been using liquid dex since the start but didn't seem to keep estrogen levels down. Switched to stane, not noticing much of a difference. Was thinking about Letro but after reading the article thinking against it. Can I use Tamoxifen during cycle for reduction in gyno and also continue to use it for PCT with Clomid after cycle?

Thanks for the write up Austinite!

JP

Have you had any blood work or are you going by symptoms? How far along on cycle are you? Might want to consider blood work as it may be working too well. Low E2 and High e2 share many symptoms.

[jdpeters]

Have blood work scheduled for the end of the month. If I had low e2 would I still be having gyno issues?

Thanks

[austinite]

Have blood work scheduled for the end of the month. If I had low e2 would I still be having gyno issues?

Thanks

Nope. That would be high E2.

[jdpeters]

Forgot to say, I am in week 9 of my cycle.

[austinite]

What AI are you using? What brand?

[jdpeters]

All ar-r brand. Started the cycle with liquid dex then switched to Stane. Made the switch cause I was getting gyno symptoms. Just didn't seem like my e2 was staying low.

Running Test cyp at 500 and Deca at 400 per week. Was taking ar-r Prami the whole time but just switched to caber. Like you said, without blood work I am just guessing. Since I switched to Stane it seems like the gyno symptoms are on the mend but was wondering if I should start Tamox?

Thanks

JP

[austinite]

I wouldnt make the switch to letro until you get blood work.